Bystolic (nebivolol) prescription available online

If you suffer from high blood pressure, Bystolic can help. Get a new prescription or refill of Bystolic from a board-certified doctor online.*

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Treats high blood pressue

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*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Bystolic (nebivolol)

Bystolic is considered a beta blocker, which reduces and blocks the activity of specific natural chemicals in the human body. These chemicals are associated with high blood pressure and risk of complications like peripheral vascular disease, heart attacks, and strokes. Like any beta blocker, this medication can only treat high blood pressure. It is ineffective against low blood pressure because it will not help balance blood pressure levels when you have hypotension.

Some conditions that Bystolic is known to treat include hypertension or high blood pressure. Bystolic is available only by prescription. It is available in a generic formulation under different brand names, including nebivolol.

Bystolic may be prescribed as a capsule. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage you are prescribed.

If you are prescribed Bystolic, be sure to complete the full course of the beta blocker unless your doctor specifically tells you to stop.

If you don’t complete your prescription, the beta blocker may not fully treat your high blood pressure. If you stop taking Bystolic suddenly, then you may notice imbalances in your blood pressure levels. People with high blood pressure who stop taking Bystolic suddenly may also experience a worsening of their condition. This can cause a further increased risk of heart failure, peripheral vascular disease, and other health problems associated with high blood pressure. Patients with high blood pressure (hypertension) will likely use this medication over a long period of time. This helps to avoid making blood flow problems worse due to high blood pressure.

Bystolic uses

There is one FDA-approved use for Bystolic, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • High blood pressure (hypertension)

    High blood pressure (hypertension) is a condition where blood pressure levels rise too high. This can lead to several problems in the body, including poor blood flow, heart failure, and more. Over time, the condition adversely affects blood vessels. When the walls of blood vessels become damaged, the risk of heart failure, heart attack, and stroke greatly increases. Beta-blockers work by blocking the action of certain channels or chemicals in the body. This helps to reduce blood pressure, which ultimately contributes to improved blood flow. When blood flow increases, it reduces the risk of inadequate blood supply to certain parts of the body.

Bystolic side effects

The side effects associated with taking Bystolic are typically mild. Most Bystolic side effects are associated with discomfort in the gastrointestinal tract.

  • Bystolic has some common side effects. They may include:

    • Nausea

    • Diarrhea

    • Stomach pain

    • Tiredness

    • Headaches

    • Insomnia (inability to fall asleep)

    Other side effects, which are less common but might be more severe, could include:

    • Shortness of breath

    • Breathlessness with mild exertion

    • Slow heartbeat

    • Uneven heartbeat

    • Swollen ankles and feet

    • Numbness in the hands or feet

    • Cold feeling in fingers or toes

    Patients also need to understand the signs of an allergic reaction. When there are allergic reactions, the patient may require emergency treatment at a medical center. Allergic reactions to Bystolic may cause trouble breathing, hives, a skin rash, and swelling in the face. An irregular heartbeat can also occur. The patient should immediately stop using these beta blockers if they experience an allergic reaction. Then, the doctor decides the best course of action, such as prescribing other beta-blockers or looking at options like calcium channel blockers.

    You should call your doctor if you notice any of these side effects or if you develop any other new or concerning symptoms. Tell your doctor if your symptoms do not improve after using the prescription medicine for some time. This can help the doctor determine if the prescription medicine is appropriate for reducing your risk of coronary artery disease, heart failure, and other diseases.

How to take Bystolic

Your pharmacist will provide you with instructions on how to take your Bystolic prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Bystolic can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed once per day. The specific dosage forms, the strength of each dose, and the number of doses does depend on the blood flow problems you have, as well as your current blood pressure levels. The healthcare professional may advise you to call your doctor immediately if you experience certain side effects.

What to avoid while taking Bystolic

Bystolic has multiple drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.

Never combine Bystolic with other beta blockers unless your doctor decides to consider this treatment option. Tell your doctor about any over-the-counter medications you use, as well as other prescription medications or herbal products. This can help to ensure you do not have to worry about drug interactions.

Some of the medications that can cause drug interactions with Bystolic to include:

  • Reserpine

  • Ticlopidine

  • Methimazole

  • Digitalis

  • Cimetidine

  • Clonidine

  • Certain antibiotics

  • Anti-malaria rugs

  • Other heart medications

  • Heart rhythm drugs

  • Medications that treat HIV/AIDs

Tell your doctor if you use any medication or herbal products that can cause your blood pressure lower.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Bystolic. Alcohol may further increase blood pressure. The high blood pressure makes the risk of serious adverse reactions more plausible in this case. Alcohol, combined with Bystolic, may also increase the risk of severe renal impairment or severe hepatic impairment.

Medication alternatives to Bystolic

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another medication called beta-blockers or a blood pressure medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Bystolic prescription FAQs

  • How much does Bystolic cost?

    To determine the cost of Bystolic, dosage forms, dosage strength, and other factors need to be taken into consideration.

  • How can I refill my Bystolic prescription?

    Since Bystolic is only available by prescription, book a virtual appointment with one of our top-rated board-certified doctors to discuss refilling your Bystolic prescription. If you qualify, you can pick up Bystolic from your local pharmacy.

  • Is it better to take Bystolic in the morning or at night?

    Tell your doctor if you find that Bystolic has a sedative effect when you take it. The medication can be taken in the morning or at night. However, the drug information may sometimes recommend using a regular dosing schedule at night. This may help to improve blood circulation and reduce the risk of high blood pressure in the morning. Taking the medication at night may also lessen specific side effects, such as severe chest pain or drowsiness.

  • Does Bystolic affect sleep?

    Bystolic produces a type of sedative effect in some people. In these cases, the medication might help the patient sleep better.

  • How long does it take for Bystolic to lower your blood pressure?

    Bystolic is not an immediate-acting drug but instead takes a bit of time to produce results. In most cases, the medication helps blood vessels relax for a period of around four hours. Note that the timing may differ if you use other medicines with Bystolic, such as certain calcium channel blockers. Talk to your healthcare provider if you are not sure.

  • Who should not take Bystolic?

    Bystolic is not recommended for pregnant people, as it may potentially cause harm to the unborn baby. Tell your doctor if you have problems with low blood sugar, trouble breathing, and a slow heartbeat. You should also advise your doctor if you have had a heart attack in the past or currently have kidney failure. When you tell your doctor about these factors, they can determine whether Bystolic or other medicines are the proper treatment.

  • What happens if I miss a dose of Bystolic?

    Take a look at the time and consider when your next dose is. You usually take about one of these medicines daily, but sometimes more. Too many drugs called beta blockers in a short period of time can cause more severe side effects, such as chest pain.

  • What happens if I take too much Bystolic?

    An overdose of Bystolic can be dangerous. Call a poison control center if you think you took too much medication.

3 simple steps to request your Bystolic prescription today 

Step 1

Book a Bystolic prescription request appointment.

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Step 2

Talk to your medical provider regarding your Bystolic prescription.

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Step 3

Pick up Bystolic.

We can send prescriptions to any local pharmacy.

Bystolic prescription pricing details

How pricing works

To get a new or refill on your Bystolic prescription, join our monthly membership and get discounted visits.

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Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
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Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.