Most major insurance plans accepted
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your Hygroton prescription today

Step 1
Book a Hygroton prescription request appointment.
Book a same day appointment from anywhere.

Step 2
Talk to your medical provider regarding your Hygroton prescription.
Visit with a doctor on your smartphone or computer.

Step 3
Pick up your Hygroton prescription.
We can send prescriptions to any local pharmacy.
Hygroton prescription pricing details
How pricing works
To get a new or refill on your Hygroton prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Hygroton prescription FAQs
How much does Hygroton cost?
Depending on your pharmacy, Hygroton (25 mg) costs around $19 for 30 tablets without insurance. Generic brands, such as chlorthalidone, can offer an affordable alternative. Price varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.
How can I refill my Hygroton prescription?
Hygroton is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.
What medications should not be taken with Hygroton?
Possible interactions with Hygroton include:
Other heart and blood pressure medications, including diuretics
Lithium
Digoxin or digitalis
Insulin or oral diabetes medicine
Steroid medicine
How much does Hygroton lower BP?
On average, Hygroton reduces blood pressure by 18/15 Hg after four weeks of treatment.
Who should not take Hygroton?
To make sure Hygroton is safe for you, tell your doctor if you have:
A serious allergic reaction to sulfa drugs
Kidney disease or severe renal disease
Heart failure
Gout
High cholesterol or triglycerides
Diabetes
What happens if I miss a dose of Hygroton?
If you miss a dose of Hygroton, take the missed dose as soon as you remember. Skip the missed dose if it’s almost time for your next dose. Avoid taking two doses to make up for a missed dose.
What happens if I take too much Hygroton?
If you've taken too much Hygroton, seek emergency medical attention or contact your local poison control center.
About Hygroton (chlorthalidone)
Hygroton is considered a thiazide diuretic, which prevents the body from absorbing too much salt. It also helps relax the blood vessels to improve blood flow.
Hygroton is used to treat high blood pressure and fluid retention (edema). Hygroton is available only by prescription. It is available in a generic formulation known as chlorthalidone, as well as under different brand names.
Hygroton may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed Hygroton, be sure to complete the full course of the diuretic unless your health care professional specifically tells you to stop. If you don’t complete your prescription, the diuretic may not fully treat your fluid retention or high blood pressure.
Hygroton uses
There are several FDA-approved uses for Hygroton, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your health care professional may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.
High blood pressure
Hygroton is FDA-approved to treat high blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems.
Edema (fluid retention)
Hygroton is FDA-approved to treat fluid retention in patients with congestive heart failure and kidney or liver trouble. It can also treat edema caused by taking steroids or estrogen.
Hygroton side effects
The side effects associated with taking Hygroton are typically mild. Most Hygroton side effects are associated with low blood pressure. Hygroton has some common side effects. They may include:
Low blood pressure (feeling dizzy or lightheaded)
Nausea or upset stomach
Dry mouth
Other side effects, which are less common but might be more severe, could include:Electrolyte imbalance
Kidney or liver trouble
Unusual bleeding
You should call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. Tell your doctor immediately if you notice any signs of liver or kidney problems.
It is not known whether Hygroton is safe and effective in children under the age of 18.
How to take Hygroton
Your pharmacist will provide you with instructions on how to take your Hygroton prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Hygroton can come in different forms and doses, so be sure to follow the specific instructions on your prescription. For adults with high blood pressure, the initial dose typically starts at 25 mg orally once daily. For adults with fluid retention, the usual dose ranges from 50 mg to 100 mg once daily.
Hygroton should be taken in the morning with food. Your doctor may increase your dose gradually to meet your blood pressure goals. Your doctor will check your blood pressure regularly, and blood tests will be done occasionally.
What to avoid while taking Hygroton
Hygroton has 441 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.
Possible drug interactions with Hygroton include:
Other heart and blood pressure medications
Lithium
Digoxin or digitalis
Insulin or oral diabetes medicine
Steroid medicine
Avoid drinking alcohol when taking Hygroton. Alcohol can cause low blood pressure, which can lead to an increased risk of dizziness, headache, fainting, and other side effects.
Avoid getting up too fast from a sitting or lying position to help your body adjust to the change in position and blood pressure, or you may feel dizzy. Make sure to drink water during exercise and in hot weather to prevent dehydration.
Medication alternatives to Hygroton
If your healthcare provider prefers to put you on another treatment altogether, they may suggest other diuretics or antihypertensive agents in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
High blood pressure
Fluid retention