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Diuretics
Diuretics prescriptions available online
Diuretics can help lower your blood pressure and available with a consultation from one of our board-certified doctors online. Get a new prescription for diuretics or refill an existing prescription today.*
Book an appointmentTreat high blood pressure effectively
Reduce edema and swelling in legs
Manage congestive heart failure symptoms
*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.
About diuretics
Diuretics are a class of drugs that consist of medications that function by increasing the amount of salt and water discharged from the body in the form of urine. Diuretics are typically prescribed to treat edema (swelling caused by more fluids retained by the body) and hypertension (high blood pressure). Still, they can be prescribed for other health problems as well. They are typically in tablet form. There are three types of prescription diuretics: thiazide, loop, and potassium-sparing diuretics. Diuretic pills are also called water pills.
What diuretics treat
A few common conditions treated by prescription diuretics are:
High blood pressure - as a blood pressure medication, diuretic pills reduce the fluid in your blood vessels, which helps lower your blood pressure.
Congestive heart failure - keeps your heart from pumping blood effectively throughout your body. This leads to a buildup of excess water in your body, which is called edema.
Swelling of the feet, ankles, lower legs, and abdomen - also known as edema- is caused by water retention in the body. A doctor can prescribe a diuretic to help reduce this fluid buildup.
Other less common conditions that diuretics may treat include:
Polycystic ovarian syndrome (PCOS)
Osteoporosis
Glaucoma
Types of diuretics
The three diuretic medications are thiazide, loop, and potassium-sparing diuretics. While each diuretic affects different parts of the kidneys, all three types make your body excrete extra fluid as urine.
Thiazide diuretics
Thiazides are the most commonly prescribed diuretics to treat high blood pressure. Thiazide diuretics work by acting directly on the kidneys to promote urine flow. In addition, they cause the blood vessels to relax, reducing blood pressure. Thiazide diuretics can cause the body to lose too much potassium, and patients may require potassium supplements.
Examples of oral thiazide diuretics include:
Loop diuretics
Loop diuretics are often prescribed to treat congestive heart failure. They work by inhibiting sodium reabsorption. Examples of loop diuretics include:
Potassium-sparing diuretics
Potassium-sparing diuretics make the kidneys excrete extra fluid as urine without interfering with the sodium-potassium exchange in the kidney cells. As a result, they do not tend to reduce the potassium level in the body like the other diuretics.
A potassium-sparing diuretic may be prescribed for people with low potassium levels, possibly due to other medications that deplete potassium. However, they do not reduce blood pressure as well as the different types of diuretics and are often prescribed together with another medicine that also lowers blood pressure.
Examples include:
How diuretics work
Prescription diuretics act on different parts of your kidneys to excrete sodium and water, resulting in more urine flow. As more salt and water are discharged from the body, water is removed from the blood, reducing fluid flow through your veins, arteries, and blood pressure.
Side effects of diuretics
When taken as prescribed, diuretics are generally safe. However, they can still cause some adverse reactions.
Some side effects of taking diuretics include:Increased urination (expected)
Dizziness
Dehydration
Muscle cramps
Joint disorders (gout)
Impotence
Loop and thiazide diuretics can lower potassium levels in the blood and cause the body to lose potassium. This can cause a condition known as hypokalemia (low potassium), which can cause heart arrhythmias and even cardiac arrest. Potassium pills are often prescribed with loop diuretic therapy to keep potassium levels safe.
Some severe side effects include:allergic reaction to the diuretics
irregular heartbeat
Note that these serious side effects are rare. Contact your doctor if you are experiencing any of these symptoms.Diuretics risks
As diuretics can affect potassium levels, doctors should not prescribe diuretics to people with severe kidney problems or Addison's disease.
In addition, tell your doctor if you have any of the following conditions before starting diuretic treatment:drug hypersensitivity
diabetes
electrolyte imbalances
gout
lupus
menstrual problems
pancreatitis
Diuretics drug interactions
Some interactions to know about are:
Antidepressants such as fluoxetine (Prozac) and venlafaxine (Effexor XR)
Cyclosporine (Restasis)
Lithium
Other diuretics (e.g. Esidrix)
Other blood pressure medications
Steroids
Warfarin
Diuretics FAQs
How should I take diuretics?
Your pharmacist will provide you with instructions on how to take your diuretics prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Prescription diuretics can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed once or twice daily. Try to adhere to a schedule. For example, for once-daily doses, you can take it first thing in the morning before or after a meal. Try to take the last one before dinner or a few hours before bedtime for twice-daily doses.
Loop and thiazide diuretics can lower potassium levels in the blood and cause the body to lose potassium. This can cause a condition known as hypokalemia (low potassium), which can cause heart arrhythmias and even cardiac arrest. Often, potassium pills are prescribed together with loop diuretic therapy to keep potassium levels safe.
If potassium pills are not prescribed, doctors may suggest you consume foods that come naturally with high levels of potassium, such as:Bananas
Oranges
Cooked spinach
Who shouldn’t take diuretics?
As diuretics can affect potassium levels, doctors should not prescribe diuretics to people with severe kidney problems or Addison's disease.
In addition, tell your doctor if you have any of the following conditions before starting diuretic treatment:drug hypersensitivity
diabetes
electrolyte imbalances
gout
lupus
menstrual problems
pancreatitis
How long does it take for diuretics to work?
It usually takes about one to two hours for diuretics to start to work
What are natural diuretics?
Natural diuretics refer to herbs and dietary supplements that contains properties similar to prescription diuretics: help your body get rid of excess salt and water. Some known examples include dandelion, ginger, juniper, hawthorn, and parsley.
However check to make you are not allergic to any of them. In addition, always check with your healthcare provider before taking a supplement to make sure it's safe for you.What foods should I avoid with diuretics?
If you are prescribed a diuretic (water pills), your doctor will recommend that you go on a low salt diet. Salt will increase fluid retention in your body. As more fluid accumulate, this can lead to swelling, most commonly seen in the feet, ankles, and legs.
Food items high in salt that should be avoided include:Canned beans with salt
Chips
Fast food
Pasta sauce
Processed foods
Salted nuts
Smoked, cured, salted, or canned meat (ex: bacon, cold cuts)
Soy sauce and Asian stir fry sauces
Vegetable or meat stocks
Loop and thiazide diuretics can lower potassium levels in the blood as cause the body to lose potassium. This can cause a condition known as hypokalemia (low potassium), which can cause heart arrhythmias and even cardiac arrest. Often, potassium pills are prescribed together with loop diuretic therapy to keep potassium levels safe.
If potassium pills are not prescribed, doctors may suggest you consume foods that comes naturally with high levels of potassium, such as:Bananas
Oranges
Cooked spinach
3 simple steps to getting diuretics online

Step 1
Book an appointment to discuss diuretics.
Book a same day appointment from anywhere.

Step 2
Talk to your doctor online.
You can see a doctor on your smartphone or computer.

Step 3
Pick up your diuretics prescription from your online doctor.
We can send diuretics to any local pharmacy.
Diuretics pricing details
How pricing works
To get diuretics online, join our monthly membership and get discounted visits.
Paying with insurance
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$14.99/month
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Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
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Paying without insurance
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$14.99/month
First month free
First visit
$129
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Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Diuretics prescription resources
Sources:
PlushCare is dedicated to providing you with accurate and trustworthy health information
Mayo Clinic. "Water retention: Are there natural diuretics?" Mayo Clinic, Mayo Foundation for Medical Education and Research, Accessed October 16, 2023, https://www.mayoclinic.org/healthy-lifestyle/weight-loss/expert-answers/water-retention/faq-20058063