Zaroxolyn (metolazone) prescription available online

Zaroxolyn is FDA-approved to treat fluid retention associated with congestive heart failure or renal disease, including a kidney disorder known as nephrotic syndrome.

Zaroxolyn has some common side effects. They may include:

• Dizziness or spinning sensation

• Drowsiness

• Joint or muscle pain

Other side effects, which are less common but might be more severe, could include:

• Chest pain

• Irregular heartbeats

• Easy bruising or bleeding

You should call your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of Zaroxolyn is not recommended in children under 18.

Zaroxolyn has many possible drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Zaroxolyn include:

• Other blood pressure medicine

• Furosemide or other diuretics

• Insulin or oral diabetes medication

• Nonsteroidal anti-inflammatory drugs (NSAIDs)

Because this medication can lower blood pressure, drinking alcoholic beverages can increase your risk of adverse reactions. Ask your doctor for medical advice before drinking alcohol.

Avoid taking metolazone if you have certain medical conditions, such as:

• Liver disease

• Systemic lupus erythematosus

• Allergic reaction to sulfa drugs

• Diabetes

• Gout

• Kidney disease

Taking this medication during pregnancy can cause side effects in the newborn baby, such as blood cell problems and jaundice (yellowing of the skin or eyes). Tell your doctor if you're pregnant or become pregnant while taking Zaroxolyn.