Antidepressant Prescriptions Available Today

Speak to a board-certified PlushCare doctor online and get antidepressant medications prescribed in 15 minutes. Anti-depression pills, also called antidepressants, are clinically proven to help with depression treatment. Our licensed doctors can also refill prescriptions and offer depression treatment online and ongoing mental health support.

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Antidepressant Medications

There are many different types of antidepressant medications, including Selective serotonin reuptake inhibitors (SSRIs), Serotonin and norepinephrine reuptake inhibitors (SNRIs), Tricyclic antidepressants (TCAs), and Monoamine oxidase inhibitors (MAOIs). Which antidepressant medications are best for you will depend on the severity of your depression, your general health, and your response to treatment. PlushCare doctors will work with you to decide which types of depression medication are best for you.

Best Antidepressants









Do Over the Counter Antidepressants Exist?

There are no FDA-approved antidepressants available over the counter. Antidepressants need to be prescribed by a doctor because they aren’t right for everyone and may interact negatively with certain medications and medical conditions. When you start a new depression medication you may experience side effects and should be closely monitored by your prescribing physician to ensure your health and safety.

How To Get Antidepressants

PlushCare makes getting antidepressant medication safe and easy. You can book a same-day appointment with a top online doctor and get antidepressant medication sent to your local pharmacy or shipped to your door following your virtual consultation. During your visit, your doctor will perform a mental health evaluation and determine if antidepressants would be an appropriate treatment, and if so, prescribe the best antidepressant for you.

Can online doctors prescribe antidepressants?

Yes. As mentioned above, online doctors are able to prescribe antidepressants to treat a variety of conditions. After diagnosing your condition the doctor will prescribe the best antidepressant for you. They will electronically send this prescription to the pharmacy of your choice.

Who can prescribe antidepressants?

Primary care physicians and psychiatrists are both qualified to prescribe antidepressants. At PlushCare, our primary care physicians commonly write prescriptions for antidepressants to treat anxiety and depression. For more complicated mental health conditions, a psychiatrist is recommended.

Can you buy antidepressants over the counter?

Antidepressant medications require a prescription. You cannot buy antidepressants over the counter and for good reason. Most antidepressants have some side effects and drug interactions, and if/which you’ll be prescribed should be left up to a doctor to determine.

Can you diagnose depression online?

Yes. Our licensed doctors use the same guidelines and clinical tools to diagnose depression online as a doctor would if you saw them in person. Schedule an appointment with a depression doctor at PlushCare today to get depression treatment online. PlushCare doctors can also help develop the right plan for you.

How long does it take for antidepressants to work?

Antidepressants usually begin working within 6 weeks. It’s important to work with your doctor on finding an antidepressant medication that works for you. Since all of our brains are different, what works for one may not necessarily work for another.

Are there any psychiatric conditions you can’t help with?

Online doctors are a perfect solution for anyone with mild to moderate anxiety or depression. However, PlushCare isn’t a good solution for patients with bipolar, schizophrenia, or psychosis, or for patients who are pregnant, breastfeeding, or have a history of suicide attempts.

Can PlushCare doctors refill my existing antidepressant?

Yes, many of our patients see PlushCare doctors to obtain refills of their antidepressant medications. Our doctors will provide a prescription refill if they determine that you qualify, based on an online medical consultation. It’s convenient and we accept all major insurance providers.

Can online doctors prescribe anxiety medication?

Yes. Our doctors commonly write prescriptions for anxiety medication for patients who qualify; that said, they cannot write prescriptions for controlled substances such as Xanax and Klonopin.

How to find a depression doctor near me

If you’re looking for a depression doctor near you, look no further. PlushCare doctors are qualified to treat depression and practice entirely online, meaning they’re always accessible to you. Our doctors can prescribe antidepressants and our therapists can offer you therapy. To find a depression doctor near you, book an online medical appointment at PlushCare to speak with one of our board-certified physicians.

How do doctors diagnose depression?

Doctors can diagnose depression in several ways, including a physical exam or psychiatric evaluation. A physiatrist may refer to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in order to provide a diagnosis for depression.

How much do antidepressants cost?

The cost of antidepressants will depend on factors such as the type of antidepressant medication, dosage prescribed, and whether you have insurance coverage. Whether the antidepressant is a brand-name or generic medication will also affect the cost.

What are the types of depression medication?

Different types of depression medication include:
– Selective serotonin reuptake inhibitors (SSRIs) 
– Serotonin–norepinephrine reuptake inhibitors (SNRIs) 
– Tricyclic antidepressants (TCAs)
– Monoamine oxidase inhibitors (MAOIs)

How do doctors decide which antidepressant to prescribe?

If a doctor decides that antidepressant medication would be an appropriate treatment, the antidepressant prescribed would be based on factors such as the patient’s current symptoms, any other medications currently being taken, any pre-existing medical conditions, and the potential for side effects.

Can a therapist prescribe antidepressants?

Only a licensed medical doctor or psychiatrist can prescribe antidepressants. While a therapist cannot prescribe antidepressants or depression medication, a therapist can refer a patient to a doctor or psychiatrist as part of their treatment for depression.

PlushCare offers online therapy for depression as part of our online mental health services.

Can primary care physicians prescribe antidepressants?

Yes, primary care physicians can work with you to prescribe antidepressants, when necessary.

This is great news for anyone working closely with their primary care doctor to create a comprehensive healthcare plan. If you or your doctor feel that your mental health treatment plan may benefit from the addition of an antidepressant, your primary care doctor can prescribe one for you.

When are antidepressants prescribed?

Antidepressants are commonly used to treat depression and anxiety, among other conditions.

The American Psychiatric Association defines depression as a very serious medical illness that negatively affects the way you think, act, as well as how you feel. When left untreated, it can greatly impact your overall quality of life, making it difficult to function or do the things that you used to enjoy. 

Depression affects millions of Americans each year. In fact, major depression is one of the most commonly seen mental health conditions in the United States.

What are some symptoms of depression?

While there are a number of symptoms of depression, some of the most commonly seen symptoms include:

-Having a loss of interest in things you used to enjoy

-Changes in appetite – weight loss/gain


-Having a hard time concentrating

-Sleep changes – this could be sleeping too much, or not being able to sleep enough

-Feeling sad

-Feeling guilty and or worthless

-Thoughts of suicide

-If you’re unsure if you’re depressed take our depression quiz here.

This quiz has compiled questions from renowned depression tests and is designed to assess mental health in terms of depressive symptoms, that said only a doctor can diagnose depression and your results should not be taken as an official diagnosis.

What antidepressants can a primary care physician prescribe?

Now that you know your primary care physician can prescribe antidepressants, let’s talk about which medications they can write a prescription for. 

When it comes to medication choice, it’s all going to come down to what you and your doctor thinks will work best based for your symptoms, other current medications and your medical history.

With that being said, here are some of the most commonly prescribed antidepressants:

-Zoloft (sertraline)

-Lexapro (escitalopram)

-Cymbalta (duloxetine hydrochloride)

-Celexa (citalopram)

-Prozac (fluoxetine)

-Paxil (paroxetine)

Talk to one of our doctors today to find out which antidepressant is best for you.

What can antidepressants be prescribed for?

While antidepressants are most commonly prescribed for depression treatment, depending on the medication, they can be prescribed for other reasons as well. 

Here are some of the conditions antidepressants are prescribed for. 




-Seasonal Affective Disorder

Can therapy treat depression?

Yes, therapy is an effective treatment approach for depression. Many people with depression choose to try therapy instead of medication or do both at the same time for a faster recovery.

PlushCare is offers online therapy across the U.S. so you can get emotional support from a licensed professional. Our trusted therapists are highly trained to treat many mental health conditions including depression and anxiety. Book a free consultation or start your first session with a licensed therapist today.

You’ll meet with your therapist once a week to receive on-going care and support as you work through your treatment.

Many therapy patients report improved mood, raised energy levels and reduced stress soon after starting therapy.

What Are Antidepressant Common Side Effects?

Some common side effects of antidepressants include:



-Dry Mouth

-Weight gain


-Loss of sex drive

Talk to your PlushCare doctor for a more complete list of antidepressant side effects.

A Note About Prescriptions

Medications are prescribed at the sole discretion of a PlushCare physician. Prescriptions for non-controlled substances can only be written after a medical evaluation. Scheduling an appointment does not guarantee that a medication can or will be prescribed.

How it Works

1 Book

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2 Chat

Visit with a doctor on your smartphone or computer.

3 Pick up

We can send prescriptions to any local pharmacy or by mail.

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Your doctor will work with you on a treatment plan, which may include therapy and/or medication. Some common prescription antidepressants our doctors prescribe are:

Depression Quiz

The following 20 questions are sourced from top depression tests with questions vetted by the Psych Central Research team. They have been carefully selected to ensure a comprehensive look at your mental health and specifically determine any symptoms of depression. When taking this test analyze your emotions from the past week. Note, this test is not a diagnostic tool, only a doctor can diagnose depression.

I do things slowly.
I'm hopeless about my future.
I have trouble concentrating.
I feel that pleasure and joy has left my life.
I struggle to make decisions.
I have lost interest in things that used to be important to me.
I'm sad and unhappy.
I'm agitated and keep moving around.
I'm fatigued and it takes great effort for me to do simple tasks.
I feel I am a guilty person and deserve punishment.
I feel like a failure.
I feel lifeless.
My sleeping pattern has changed, I either sleep too much or too little.
I fantasize about suicide.
I plan how I might kill myself.
I feel trapped or caught.
I feel depressed even when good things happen to me.
Good things happen to me.
Without dieting I have lost or gained weight.
I feel alone, no one is there for me.

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