Edecrin (ethacrynic acid) prescription available online

If you are suffering from edema, Edecrin (ethacrynic acid) can help. Get a new prescription or refill of Edecrin from a board-certified doctor online.*

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Improve kidney function and reduces swelling

Available as a tablet, powder, or intravenous injection

Follow full course for effective treatment

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Edecrin (ethacrynic acid)

Edecrin is a loop diuretic (water pill) that prevents the body from absorbing excess salt. Edecrin is used to treat edema (fluid retention) in people with congestive heart failure, liver disease, or kidney disease.

Edecrin is available only by prescription. It is available in a generic formulation as well as under different brand names, including ethacrynic acid.

Edecrin may be prescribed as a tablet, powder, or intravenous injection. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Edecrin, be sure to complete the full course of the diuretic unless your healthcare professional specifically tells you to stop. If you don’t complete your prescription, the diuretic may not fully treat your edema.

Edecrin uses

There are several FDA-approved uses for Edecrin, but your healthcare professional may also prescribe it off-label to treat other medical conditions.

Your doctor may prescribe Edecrin for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Edema (fluid retention)

    Edecrin is FDA-approved to treat edema in patients with congestive heart failure, liver disease, and renal disease, including nephrotic syndrome. By eliminating fluid accumulation, Edecrin improves kidney function and reduces swelling.

Edecrin side effects

The side effects associated with taking Edecrin are typically mild. Most Edecrin side effects are associated with gastrointestinal discomfort.

  • Edecrin has some common side effects. They may include:

    • Nausea, vomiting, or upset stomach

    • Loss of appetite

    • Headache or tiredness

    • Blurred vision

    • Trouble swallowing

    Other side effects, which are less common but might be more severe, could include:

    • Weight loss

    • Severe or watery diarrhea

    • Severe dizziness

    Tell your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. Edecrin may be used to treat congenital heart failure or nephrotic syndrome in pediatric patients.

How to take Edecrin

Your pharmacist will provide you with instructions on how to take your Edecrin prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Edecrin can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The initial oral dose of Edecrin is typically 50 mg once daily. Take Edecrin after a meal unless your doctor tells you otherwise.

What to avoid while taking Edecrin

Edecrin has 434 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Edecrin include:

  • Digoxin, digitalis

  • Blood pressure medications

  • Antibiotics, including those given through intravenous injection

  • Blood thinners

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

  • Steroid medicine

Alcohol may have additive effects in lowering blood pressure, which can increase your risk of adverse reactions while taking ethacrynic acid. Ask your doctor for medical advice before drinking alcohol.

Medication alternatives to Edecrin

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other loop diuretics or edema medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Edecrin prescription FAQs

  • How much does Edecrin cost?

    Depending on your pharmacy, Edecrin oral tablets cost around $2,583 for one hundred 25 mg tablets without insurance. Fortunately, generic brands, such as ethacrynic acid, may offer an affordable alternative. Price varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Edecrin prescription?

    Edecrin is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Can Edecrin be given with NSAIDs?

    No, Edecrin should not be given with NSAIDs. When taken together, NSAIDs can decrease the effectiveness of loop diuretic agents.

  • Is Edecrin taken orally?

    Yes, Edecrin is typically administered orally. Your doctor may prescribe an intravenous injection if you cannot take medications orally.

  • What kind of diuretic is Edecrin?

    Edecrin is a loop diuretic. Loop diuretics work to remove certain electrolytes and extra fluid to prevent swelling.

  • Who should not take Edecrin?

    Avoid taking ethacrynic acid if you have certain medical conditions, such as:

    • Heart disease

    • Electrolyte imbalance

    • Severe kidney disease

    • Allergic reaction to ethacrynic acid

    It is not known whether ethacrynic acid can pass into breast milk Avoid taking ethacrynic acid while breast-feeding.

  • What happens if I miss a dose of Edecrin?

    If you miss a dose of Edecrin, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Edecrin?

    If you've taken too much Edecrin, call your doctor immediately or contact your local poison control center. If you experience serious adverse reactions, seek emergency medical attention.

3 simple steps to request your Edecrin prescription today 

Step 1

Book an Edecrin prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Edecrin prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Edecrin prescription.

We can send prescriptions to any local pharmacy.

Edecrin prescription pricing details

How pricing works

To get a new or refill on your Edecrin prescription, join our monthly membership and get discounted visits.

Paying with insurance



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30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.