We accept these insurance plans and many more!
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your hydrochlorothiazide prescription today

Step 1
Book a hydrochlorothiazide request appointment.
Book a same day appointment from anywhere.

Step 2
Talk to your medical provider regarding your hydrochlorothiazide prescription.
Visit with a doctor on your smartphone or computer.

Step 3
Pick up your hydrochlorothiazide prescription.
We can send prescriptions to any local pharmacy.
Hydrochlorothiazide prescription pricing details
How pricing works
To get a new or refill on your hydrochlorothiazide prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Hydrochlorothiazide prescription FAQs
How much does hydrochlorothiazide cost?
Depending on your pharmacy, hydrochlorothiazide oral tablets cost around $12 for thirty 12.5 mg tablets without insurance. Hydrochlorothiazide is a generic medication. Brand names, such as Microzide, may cost more.
How can I refill my hydrochlorothiazide prescription?
To refill your Microzide prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.
Who should not take hydrochlorothiazide?
Avoid taking hydrochlorothiazide if you have certain medical conditions, such as:
Allergic reactions to Microzide
Lupus
High cholesterol
High blood sugar (diabetes)
Liver disease
Kidney disease or kidney failure
Renal function disorders
What should you avoid when taking hydrochlorothiazide?
Avoid drinking alcohol while taking hydrochlorothiazide. Alcohol can further lower your blood pressure, which may lead to dizziness, lightheadedness, and serious side effects. Avoid getting up too fast from a sitting or lying position.
Avoid driving and doing other hazardous tasks until you know how Microzide affects you.What medications interact with hydrochlorothiazide?
Possible drug interactions with Microzide include:
Lithium
Dofetilide
Other loop diuretics and antihypertensive agents
Nonsteroidal anti-inflammatory drugs, such as aspirin
What happens if I miss a dose of hydrochlorothiazide?
If you miss a dose of hydrochlorothiazide, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.
What happens if I take too much hydrochlorothiazide?
If you've taken too much hydrochlorothiazide, seek emergency medical help or contact your local poison control center.
About hydrochlorothiazide
Hydrochlorothiazide is considered a thiazide diuretic (water pill), which helps your body get rid of extra fluid and water by increasing urination.
Hydrochlorothiazide is used to treat high blood pressure (hypertension) and fluid retention (edema). Hydrochlorothiazide is available only by prescription. It is available in a generic formulation as well as under different brand names, including Microzide.
Hydrochlorothiazide may be prescribed as a tablet, oral capsule, or liquid suspension. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed hydrochlorothiazide, be sure to complete the full course of the thiazide diuretic unless your doctor specifically tells you to stop. If you don’t complete your prescription, the thiazide diuretics may not fully treat your high blood pressure or fluid retention.
Hydrochlorothiazide uses
There are several FDA-approved uses for hydrochlorothiazide, but it may also be used off-label to treat other conditions. Your online healthcare professional may prescribe it for any of the following common reasons.
It’s also possible that healthcare professionals may prescribe Microzide for other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.
High blood pressure
Microzide is FDA-approved to treat high blood pressure. It may be prescribed alone or in combination with other antihypertensive agents. By removing extra fluid from your body, Microzide keeps your heart from working too hard to pump blood, which lowers blood pressure.
Edema
Microzide is FDA-approved to treat edema. It increases urination to remove extra salt and fluid from the body.
Hydrochlorothiazide side effects
The side effects associated with taking hydrochlorothiazide are typically mild. Most hydrochlorothiazide side effects are associated with gastrointestinal discomfort.
Hydrochlorothiazide has some common side effects. They may include:
Nausea, vomiting, or stomach cramps
Feeling dizzy, tired, or weak
Diarrhea or constipation
Other side effects, which are less common but might be more severe, could include:Shortness of breath or chest pain
Purple skin rash or skin pain
Electrolyte imbalance
Eye pain or vision problems
Tell your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of hydrochlorothiazide is not approved in children under 18 years of age.
How to take hydrochlorothiazide
Your pharmacist will provide you with instructions on how to take your hydrochlorothiazide prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Hydrochlorothiazide can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The typical starting dose of Microzide is 12.5 mg once daily to treat high blood pressure or edema. A dosage adjustment may be required depending on your treatment plan.
What to avoid while taking hydrochlorothiazide
Hydrochlorothiazide has 427 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or herbal products, as well as over-the-counter medications.
Possible drug interactions with Microzide include:
Lithium
Dofetilide
Other loop diuretics and antihypertensive agents
Nonsteroidal anti-inflammatory drugs, such as aspirin
When taking hydrochlorothiazide, drinking alcohol may have additive effects in lowering your blood pressure. Ask your doctor for medical advice about side effects before drinking alcohol.
Microzide increases your skin's sensitivity to the sun, which can lead to an increased risk of skin cancer. Wear protective clothing and sunscreen when taking hydrochlorothiazide.
Medication alternatives to hydrochlorothiazide
If your healthcare provider prefers to put you on another treatment altogether, they may suggest other thiazide diuretics, potassium-sparing diuretics, or loop diuretics in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
High blood pressure
Edema