Demadex (torsemide) prescription available online 

If you are suffering from edema that is usually associated with heart, kidney, or liver failure, Demadex (torsemide) can help. Get a new prescription or refill of Demadex from a board-certified doctor online.*

Book an appointment

Helps reduce high blood pressure

Available as a tablet and injectable form

Treats fluid retention in people with heart failure, liver disease, and more

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Demadex 

Demadex is considered a loop diuretic, which functions by helping the body get rid of excess water and salt. Like any diuretic, this medication can only be used for treating edema (swelling caused by fluid retention) and hypertension (high blood pressure).

Demadex is typically used in adults with congestive heart failure, kidney disease, or liver disease. Demadex is available only by prescription. It is available in a generic formulation under the name torsemide

Demadex may be prescribed as a tablet and injectable forms. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed. Demadex in tablet form (torsemide oral) is usually taken once or twice daily. The injectable form is used when torsemide oral is not tolerated or when quick diuresis is needed.

If you are prescribed Demadex, be sure to complete the full course of the loop diuretic unless your doctor specifically tells you to stop.

If you don’t complete your prescription, the loop diuretic may not fully treat your edema or hypertension (high blood pressure). 

Demadex's most common side effects include hypotension, electrolyte imbalance, and dehydration. Demadex should be taken with food or milk to prevent stomach upset.

Demadex uses

There are many FDA-approved uses for Demadex, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your physician may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • High blood pressure

    Demadex is commonly prescribed to treat patients with high blood pressure, helping by lowering blood pressure.

  • Edema

    Fluid retention (edema) occurs when the body contains too much fluid, leading to swelling in the legs, feet, and ankles. If left untreated, edema can lead to serious health complications such as kidney disease and heart disease. Demadex help with increased urination to reduce the amount of fluid in the body and relieve edema symptoms.  

  • Chronic heart failure

    Demadex is a medication used to treat patients with congestive heart failure. It helps with heart disease management by removing excess fluid from the body, reducing congestion, and improving heart function. 

  • Renal disease

    Diuretics are also used in chronic renal disease to treat edema.

  • Hepatic cirrhosis

    Demadex is specifically approved to treat fluid retention in people with hepatic cirrhosis, a condition that occurs when the liver is damaged. Cirrhosis can cause fluid to build up in the abdomen (ascites) and sides (edema).

Demadex side effects

  • The side effects associated with taking Demadex are typically mild to moderate. Demadex has some common side effects. They may include:

    • Additional swelling

    • Diarrhea, constipation, and nausea

    • Headaches or dizziness

    • Chest pain

    • Weak muscles

    • Insomnia

    • Rhinitis

    • Excessive urination

    Other side effects, which are less common but might be more severe, could include:

    • Problems with vision, or eye pain

    • Weak or painful muscles

    • Dehydration symptoms such as dry mouth or throat, extreme thirst, muscle cramps or weakness, confusion, or decreased urination

    • Drowsiness or lightheadedness

    • Fast or uneven heartbeat

    • Numbness or tingling sensations

    • Nausea or vomiting

    • Constipation

    Some uncommon but severe side effects of Demadex include:

    • Worsening of kidney disease

    • Worsening of gout

    • Risk of hearing loss is considered higher when Demadex is combined with other medications known to cause hearing loss

    • High blood glucose concentrations in diabetics

    Seek emergency medical attention if have any of the above symptoms.

    If you experience any of these side effects or develop any new or concerning symptoms while taking Demadex, it is important to call your doctor immediately.

    Demadex is only approved for people 18 years old or older.

How to take Demadex

Your pharmacist will provide you with instructions on how to take your Demadex prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Demadex can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed once or twice daily.

Torsemide is available in two forms:

  • The oral form may be taken with or without food. Diuresis usually begins within an hour after taking the tablet.

  • The IV form is recommended when rapid action is needed. Diuresis usually begins within 10 mins of administering the drug.

Recommended initial doses:

  • Edema from heart failure: 10 or 20 mg

  • Edema from kidney failure: 20 mg

  • Edema from liver failure: 5 or 10 mg

  • Hypertension: 5 mg. Demadex may be taken in combination with other hypertension medications

Demadex can cause dizziness, drowsiness, and lightheadedness. This is more likely to occur when you first start taking the drug or if you take a high dose. To avoid this problem, take Demadex at bedtime and get up slowly after lying down. These side effects can improve after a few days as your body adjusts to the medication. Call your doctor if these problems persist.

Demadex may cause fluid and electrolyte problems in people with liver disease and cause gouty episodes in people with gout. Demadex should not be used in people with a coma caused by hepatic encephalopathy, as it could worsen the condition. If you have any of these conditions, talk to a health care professional for medical advice.

What to avoid while taking Demadex

Demadex has many drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

The most common or serious interactions to know about are:

  • Other diuretics

  • Antifungals

  • Other blood pressure medications

  • NSAIDs (e.g., ibuprofen)

  • Steroids

  • Intravenous antibiotics

  • Lithium

  • Warfarin

Demadex can interact with certain foods and herbs, increasing or decreasing the drug's effectiveness. Diuretic herbs, such as dandelion and uva ursi, can interact with Demadex and cause additional diuresis. Licorice should not be used with Demadex as it can worsen the side effects of the drug. Demadex also interacts with tobacco. The combined use of tobacco may worsen the side effects of Demadex.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Demadex.

Drinking alcohol can increase some of the side effects of Demadex, and may also lead to low blood pressure. You should avoid or limit drinking alcohol while taking Demadex.

Medication alternatives to Demadex

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another diuretic or a medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Demandex prescription FAQs

  • How much does Demadex cost?

    The cost for Demadex oral tablet 10 mg is around $309 for a supply of 100 tablets, depending on the pharmacy you visit. Price varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Demadex prescription?

    Demadex is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take torsemide?

    Demadex is only approved for people 18 years old or older. Demadex may be dangerous for people with certain conditions. Be sure to tell your doctor if you have:

    • Difficulty urinating

    • Liver, kidney, or heart issues

    • An allergy to sulfa drugs or povidone

  • How quickly does Demadex work?

    Torsemide is available in two forms, which differ in how quickly they work:

    • The oral form usually begins to work within an hour after taking the tablet.

    • With the IV form, diuresis usually begins within 10 mins of administering the drug.

  • Does torsemide affect blood pressure?

    Torsemide works by causing the kidneys to remove more salt and water from the blood, lowering blood pressure in most people.

  • What is the best time to take Torsemide?

    Demadex can cause dizziness, drowsiness, and lightheadedness. This is more likely to occur when you first start taking the drug or if you take a high dose. To avoid this problem, take Demadex at or close to bedtime.

  • What happens if I miss a dose of Demadex?

    If you miss a dose of Demadex, skip the missed dose and go back to your regular dosing schedule. Avoid double doses.

  • What happens if I take too much Demadex?

    Taking too much Demadex can lead to serious side effects, including electrolyte imbalances, dehydration, and low blood pressure. If you are suffering from a Demadex overdose, call your local poison control center or healthcare provider immediately. An overdose of Demadex can be fatal, so it is important to get emergency help right away.

3 simple steps to request your Demadex prescription today 

Step 1: Book an appointment

Step 1

Book a Demadex prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Demadex prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Demadex prescription.

We can send prescriptions to any local pharmacy.

Demadex prescription pricing details

How pricing works

To get a new or refill on your Demadex prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.