Lozol (indapamide) prescription available online

If you are suffering from edema or hypertension, Lozol (indapamide) can help. Get a new prescription or refill of Lozol from a board-certified doctor online.*

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FDA-approved to treat high blood pressure and edema

Available as an oral tablet

Promoting more urination, minimizing fluid retention

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Lozol (indapamide) 

Lozol is considered a thiazide diuretic, which acts on tubules in the kidneys that absorb salts. Indapamide works by blocking the reabsorption of salts, decreasing salt retention, increasing urination, and reducing fluid retention.

Some conditions that Lozol is known to treat include high blood pressure and edema (salt and fluid retention). Lozol is available only by prescription. It is available in a generic formulation such as indapamide, as well as under different brand names. 

Lozol may be prescribed as an oral tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Lozol, be sure to complete the full course of the diuretic unless your doctor specifically tells you to stop. If you don’t complete your prescription, the diuretic may not fully treat your high blood pressure or edema.

Lozol uses

There are many FDA-approved uses for Lozol, but it may also be used off-label to treat other conditions. Your online clinician may prescribe it for any of the following common reasons. It’s also possible that your health care provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Hypertension (high blood pressure)

    Lozol is FDA-approved to treat high blood pressure in hypertensive patients. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems.

  • Edema

    Lozol is FDA-approved to treat edema in patients with congestive heart failure. Like other diuretics, Lozol causes you to make more urine, which helps the body get rid of extra salt and water.

Lozol side effects

  • The side effects associated with taking Lozol are typically mild. Most Lozol side effects are associated with dizziness and tiredness. Common side effects of Lozol may include:

    • Increased urination (desirable)

    • Dizziness, weakness, or tiredness

    • Upset stomach (constipation, pain, diarrhea, or loss of appetite)

    • Blurred vision

    • Headache

    Call your doctor and stop using indapamide if you experience any of the following side effects:

    • Leg cramps, muscle pain, or limp feeling

    • Rash, particularly one that blisters or peels

    • Severe weakness, loss of coordination, or feeling unsteady

    • Eye pain or vision loss

    • Electrolyte imbalance

    You should call your doctor if you notice any of adverse reactions, or if you develop any other new or concerning symptoms. The use of Lozol in young children under age 12 is not recommended.

How to take Lozol

Your pharmacist will provide you with instructions on how to take your Lozol (indapamide) prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Lozol can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed as a single oral dose per day. While using Lozol, your doctor may recommend frequent medical checks for blood pressure.

Indapamide is taken as an oral tablet, once daily. Commonly prescribed doses include:

  • For edema, the typical starting dose is 2.5 mg per day. Indapamide is used with caution for patients with certain liver and kidney issues and dosages may be different.

  • For hypertension, the typical starting dose is 1.25 mg per day. This may be increased to 5 mg per day. Another hypertension medication is added if 5 mg does not achieve the desired effect.

The maximum daily dose is 5 mg. Other starting doses may be recommended for elderly and younger patients.

What to avoid while taking Lozol

Indapamide has 446 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other drugs or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Lozol include:

Drinking alcohol while taking Lozol may have additive effects in lowering your blood pressure, which can lead to headache, dizziness, and possibly other adverse reactions. Ask your doctor for medical advice before consuming alcohol.

Medication alternatives to Lozol

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another thiazide diuretic or an antihypertensive medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Indapamide prescription FAQs

  • How much does Lozol cost?

    Depending on your pharmacy, indapamide 1.25 mg typically costs around $37 for 100 oral tablets. Price also varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Lozol prescription?

    To refill your Lozol prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Lozol?

    To make sure Lozol is safe for you, tell your doctor if you have:

    • Kidney disease or severe renal disease

    • Abnormal liver function tests

    • Low levels of potassium in your blood

    • Gout

    • Diabetes

    • Lupus

  • What happens if I miss a dose of Lozol?

    If you miss a dose of Lozol, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Lozol?

    If you've taken too much Lozol, seek emergency medical attention or contact your local poison control center. Be sure to follow your doctor's advice on drinking liquids to avoid a fluid or electrolyte imbalance.

  • What are the benefits of indapamide?

    Indapamide is effective in treating edema and hypertension, usually with minimal side effects. Indapamide and other thiazide diuretics work better for treating edema than loop diuretics such as Demadex. However, indapamide and other thiazide diuretics do not work as well as loop diuretics for treating hypertension.

  • What class of drugs is indapamide?

    Indapamide belongs to a class of drugs called thiazide diuretics.

  • Is indapamide a good blood pressure drug?

    Yes, indapamide is an effective blood pressure medication when taken as directed.

  • Is Lozol a thiazide?

    Yes, Lozol (indapamide) is a type of thiazide diuretic.

3 simple steps to request your Lozol prescription today 

Step 1

Book a Lozol prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Lozol prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Lozol prescription.

We can send prescriptions to any local pharmacy.

Lozol prescription pricing details

How pricing works

To get a new or refill on your Lozol prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.