Tradjenta (linagliptin) prescription available online 

Our doctors are here to help. If you are suffering from type 2 diabetes, Tradjenta can help. Get a new prescription or refill of Tradjenta to lower blood sugar levels from a board-certified doctor online.

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About Tradjenta (linagliptin)

Tradjenta (linagliptin) is a type 2 diabetes medication that lowers blood sugar levels. It belongs to a class of drugs dipeptidyl peptidase-4 (DPP-4) inhibitors, which stimulate the pancreas to increase insulin production and slow the liver's production of glucose.

Tradjenta is available only by prescription. It is available in a generic formulation as well as under the name linagliptin.

Tradjenta may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Tradjenta, be sure to complete the full course unless your doctor specifically tells you to stop. If you don’t complete your prescription, Tradjenta may not fully treat your high blood sugar.

Tradjenta uses

There are several FDA-approved uses for Tradjenta, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe Tradjenta for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Type 2 diabetes

    Tradjenta is FDA-approved to lower blood sugar levels in adults with type 2 diabetes. It works by regulating insulin production after eating. Tradjenta is typically prescribed for long-term use in combination with a balanced diet and exercise.

    Tradjenta is not recommended for the treatment of type 1 diabetes.

Tradjenta side effects

The side effects associated with taking Tradjenta are typically mild. Individuals taking Tradjenta report a variety of side effects, and side effects may vary from patient to patient.

  • The side effects of Tradjenta may include:

    • Stuffy or runny nose

    • Sore throat

    • Cough

    • Diarrhea or constipation

    • Urinary tract infection (UTI)

    • Weight gain

    Other side effects, which are less common but might be more severe, could include:

    • Allergic reactions

    • Severe joint pain

    • Severe low blood sugar levels (severe hypoglycemia)

    • Pancreatitis

    Call your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. Tradjenta is not FDA-approved for children under the age of 12.

How to take Tradjenta (linagliptin)

Your pharmacist will provide you with instructions on how to take your Tradjenta prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

The recommended starting dose for Tradjenta is a 5 mg pill once daily. Tradjenta can be taken with or without food. Make sure to follow your treatment plan, including diet, exercise, and weight control, to control your blood sugar.

If you're taking Tradjenta with other forms of insulin, your dosage of either drug may be lowered to avoid hypoglycemia (low blood sugar).

What to avoid while taking Tradjenta

Tradjenta has several drug interactions. Don’t change what you're taking without checking with your healthcare professional or pharmacist. That includes other medications, supplements, and over-the-counter drugs.

Some possible drug interactions with Tradjenta include:

  • Amlodipine

  • Aspirin

  • Furosemide (Lasix, Diaqua-2, Lo-Aqua)

  • Glimepiride (Amaryl)

  • Glipizide (Glucotrol, Glucotrol XL, GlipiZIDE XL)

  • Insulin

  • Invokana (canagliflozin)

  • Lantus (insulin glargine)

  • Levothyroxine (Synthroid, Levoxyl, Tirosint, Eltroxin, Levothroid, Levothyrox, Euthyrox, Unithroid, Levo-T, Oroxine, L Thyroxine Roche, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)

  • Lisinopril (Zestril, Prinivil, Qbrelis)

Beta-blockers may also interact with Tradjenta. These include:

Talk with your doctor about drinking alcohol while taking Tradjenta. Alcohol may worsen the side effects of Tradjenta. It can also make it harder to control high blood sugar.

Medication alternatives to Tradjenta

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another DPP-4 inhibitor or another type of type 2 diabetes drug. Here are some common doctor-recommended alternatives based on your health issue:

Tradjenta prescription FAQs

  • How much does Tradjenta cost?

    Depending on your pharmacy, Tradjenta oral tablets cost around $541 for thirty 5 mg tablets. Fortunately, generic brands, such as linagliptin, offer an affordable alternative.

  • How can I refill my Tradjenta prescription?

    To refill your Tradjenta prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy, if you qualify.

  • Who should not take Tradjenta?

    You should not take Tradjenta if you have certain medical conditions, such as:

    • Low blood sugar levels

    • Kidney problems

    • You're pregnant or planning to become pregnant

    • Allergic reaction to linagliptin

    • Pancreatitis

    • Chronic heart failure

  • What happens if I miss a dose of Tradjenta?

    If you miss a dose of Tradjenta, take the missed dose as soon as you remember. However, you should skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for the missed dose.

  • What happens if I take too much Tradjenta?

    If you've taken too much Tradjenta, call your doctor immediately or contact your local poison control center.

  • Is Tradjenta better than metformin?

    While Glucophage (metformin) and Tradjenta both lower blood sugar, metformin is often the first-line treatment to control blood sugar. However, Tradjenta may be the better option if you cannot tolerate the stomach side effects of metformin.

  • What is Tradjenta used for?

    Tradjenta is used to reduce blood sugar levels in adults with type 2 diabetes.

  • When should Tradjenta be taken?

    You should take Tradjenta at the same time each day. You can take Tradjenta with or without food.

3 simple steps to request your Tradjenta prescription today

Step 1

Book a Tradjenta prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Tradjenta prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Tradjenta prescription.

We can send prescriptions to any local pharmacy.

Tradjenta prescription pricing details

How pricing works

To get a new or refill on your Tradjenta prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.

Tradjenta prescription resources