Glucotrol (glipizide) prescription available online

If you are suffering from type 2 diabetes mellitus, Glucotrol (glipizide) can help. Get a new prescription or refill of Glucotrol from a board-certified doctor online.*

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Manage blood sugar levels

Available by tablet

Save up to 37% on Glucotrol with RX discount card*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Glucotrol (glipizide)

Glucotrol is an oral diabetes medicine, which helps control blood sugar levels by promoting insulin production. Glucotrol is used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Glucotrol is available only by prescription. It is available in a generic formulation as glipizide, as well as under different brand names.

Glucotrol may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Glucotrol, be sure to complete the full course of the diabetes medication unless your healthcare professional specifically tells you to stop. If you don’t complete your prescription, the diabetes medication may not fully treat your type 2 diabetes mellitus.

Glucotrol uses

There is 1 FDA-approved use for Glucotrol, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your doctor may prescribe Glucotrol for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your healthcare professional or pharmacist.

  • Type 2 diabetes mellitus

    Glucotrol is FDA-approved to manage blood sugar in adults with type 2 diabetes mellitus in combination with diet and exercise. It does not treat type 1 diabetes or diabetic ketoacidosis.

Glucotrol side effects

  • The side effects associated with taking Glucotrol are typically mild. Most Glucotrol side effects are associated with diarrhea.

    Glucotrol has some common side effects. They may include:

    • Diarrhea, constipation, and gas

    • Dizziness or drowsiness

    • Skin rash, redness, and itching

    Other side effects, which are less common but might be more severe, could include:

    • Severe hypoglycemia (low blood sugar)

    • Fast heart rate

    • Stomach pain

    • Allergic reactions

    You should call your doctor for medical advice if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of Glucotrol is not recommended in children under the age of 18.

How to take Glucotrol

Your pharmacist will provide you with instructions on how to take your Glucotrol prescription. Be sure to read your prescription label and follow the instructions as directed by your doctor. Call your doctor or pharmacy if you have any questions.

Glucotrol can come in different forms and doses, so be sure to follow the specific instructions on your prescription. Both Glucotrol immediate-release tablets and extended-release tablets have a starting dose of 5 mg orally once a day. Glucotrol should be taken 30 minutes before your first meal of the day.

What to avoid while taking Glucotrol

Glucotrol has 453 drug interactions. Don’t change what you are taking without checking with your doctor for medical advice. That includes prescription drugs, supplements, and other drugs.

Possible drug interactions with Glucotrol include:

  • Low-strength aspirin

  • Glucophage (metformin)

  • Lantus (insulin glargine)

  • Lasix (furosemide)

  • Zoloft (sertraline)

Alcohol may affect blood glucose levels in people with type 2 diabetes. However, moderate alcohol consumption is safe if your diabetes is under control. Talk to your doctor before drinking alcohol while taking oral hypoglycemic agents.

Medication alternatives to Glucotrol

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other diabetes medications or other oral hypoglycemic agents in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Glucotrol prescription FAQs

  • How much does Glucotrol cost?

    Depending on your pharmacy, Glucotrol costs around $340 for ninety 10 mg tablets without insurance. Fortunately, generic brands, such as glipizide, may offer a more affordable alternative. Price also varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Glucotrol prescription?

    To refill your Glucotrol prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy, if you qualify.

  • Who should not take Glucotrol?

    Avoid taking Glucotrol if you have certain medical conditions, such as:

    • Liver disease or kidney disease

    • Chronic diarrhea

    • Enzyme deficiency (glucose-6-phosphate dehydrogenase deficiency (G6PD))

    • Diabetic ketoacidosis

    • Allergic reaction to glipizide

  • What happens if you take glipizide on an empty stomach?

    If you don't eat within 30 minutes of taking glipizide, your blood sugar may drop too low, leading to an increased risk of hypoglycemia. Severe low blood sugar may require urgent medical treatment.

  • What happens if you take glipizide with food?

    When you take glipizide with food, it helps decrease the level of sugar in your blood. It can also help you avoid gastrointestinal side effects, such as nausea.

  • What happens if I miss a dose of Glucotrol?

    If you miss a dose of Glucotrol, take the missed dose before your next meal. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Glucotrol?

    If you've taken too much Glucotrol, call your doctor immediately or contact your local poison control center. If symptoms of low blood occur, drink fruit juice, honey, or non-diet soda.

3 simple steps to request your Glucotrol prescription today 

Step 1

Book a Glucotrol prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Glucotrol prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Glucotrol prescription.

We can send prescriptions to any local pharmacy.

Glucotrol prescription pricing details

How pricing works

To get a new or refill on your Glucotrol prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.