Soliqua (insulin glargine and lixisenatide) prescription available online

The side effects associated with taking Soliqua 100/33 are typically mild. Most Soliqua side effects are associated with low blood sugar. Soliqua has some common side effects. They may include:

• Low blood sugar levels

• Nausea or diarrhea

• Headache

• Cold symptoms, such as sore throat or runny nose

• Skin reaction at the injection site

Other side effects, which are less common but might be more severe, could include:

• Low potassium or low blood pressure

• Severe low blood sugar (hypoglycemia)

• Sudden weight gain

• Allergic reactions

• Serious infection or severe rash at the injection site

You should call your healthcare professional if you notice any of these side effects, or if you develop any other new or concerning symptoms. It is not known whether Soliqua 100/33 is safe and effective in children under 18 years of age.

Soliqua has 395 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other prescription drugs or supplements, as well as over-the-counter medicines. 

Possible drug interactions with Soliqua include:

• Antibiotic medications

• Tylenol (acetaminophen)

• Birth control pills (take at least one hour before or 11 hours after Soliqua 100/33)

• Other diabetes medicines, such as pioglitazone or rosiglitazone

Drinking alcohol while taking Soliqua 100/33 can cause severe low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia), depending on how much you drink. Talk to your healthcare provider before you drink alcohol.

Avoid taking Soliqua 100/33 if you have certain medical conditions, such as:

• Severe allergic reaction to insulin products

• Pancreatitis or gallbladder disease

• Problems digesting food

• Liver or kidney disease

• Heart failure