Novolin R (regular insulin) prescription available online 

If you are suffering from type 1 or type 2 diabetes, Novolin R (regular insulin) can help. Get a new prescription or refill of Novolin R today from a board-certified doctor online.*

Book an appointment

Monitor your blood glucose if a dose is missed

Treat both type 1 and type 2 diabetes

Considered a short-acting insulin

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Novolin R (regular insulin)

Novolin R is a medication used to treat both type 1 and type 2 diabetes. It's a short-acting insulin that works to lower blood sugar levels in the body. It is a type of human insulin. This medication requires a prescription and can be obtained under different names, such as Novolin R Relion FlexPen.

Managing your diabetes correctly means taking Novolin R exactly as your doctor prescribed. Depending on the specific formulation and insulin dose they prescribed, the directions may vary. You'll need to give yourself an injection into the fatty tissue located in your upper arm, thigh, buttocks, or stomach area.

This brand of insulin is five times more potent than others, so it's important to be careful with the dosage to avoid low blood sugar. If you stop taking the medication abruptly before finishing the whole prescription, the human insulin can affect blood glucose control and leave your diabetes untreated.

Novolin R uses

Novolin R has been approved by the FDA for the following used, but it may also be recommended by your online clinician for other conditions. If you have any questions about why this medication has been prescribed, please consult your online doctor or pharmacist.

  • Type 1 and type 2 diabetes mellitus

    Novolin R is a short-acting insulin used to treat type 1 and type 2 diabetes mellitus.

  • Calcium channel blocker or beta-blocker overdose

    High-dose insulin is used to treat beta-blocker and calcium channel blocker overdoses.

Novolin R (regular insulin) side effects

  • The side effects associated with taking Novolin R are typically mild. Common side effects include:

    • Injection site redness

    • Swelling at the injection site

    • Hypoglycemia (low blood sugar)

    Other side effects, which are less common but might be more severe, could include:

    • Dizziness

    • Hypersensitivity reaction

    • Muscle cramps

    If you happen to notice any of these side effects or encounter any new or concerning symptoms, such as a serious allergic reaction, it's best to tell your doctor.

How to take Novolin R

Your pharmacist will provide instructions on how to take your Novolin R prescription. It's important to read the label and follow the directions carefully. If you have any questions, don't hesitate to contact your doctor or pharmacy.

Keep in mind that Novolin R can come in various forms and doses, so be sure to follow the specific instructions provided on your prescription. It is typically prescribed 3 times per day as a human insulin injection. Some specific instructions may include not to use the medication if the solution is viscous or cloudy.

What to avoid while taking Novolin R

Novolin R has several drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. Possible drug interactions with Novolin R can include, but are not limited to:

It is important to closely monitor your blood sugar when taking Novolin R. 

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Novolin R. Some research shows that regular alcohol consumption may increase your risk of high blood sugar (hyperglycemia). Alcohol may also reduce the medication’s ability to do its job, making it harder to control your diabetes.

Medication alternatives to Novolin R

If your healthcare provider prefers to put you on another treatment altogether, they may suggest a different short-acting insulin or oral diabetes drugs. Here are some commonly recommended options from our doctors, based on your health issue:

Novolin R prescription FAQs

  • How much does Novolin R cost?

    Novolin R costs around $155 for a 10 mL supply, depending on your pharmacy. The price may be significantly lower depending on your insurance coverage. You can also save up to 80% on prescriptions as a PlushCare member with our prescription discount card, paying without insurance.

  • How can I refill my Novolin R prescription?

    To get a refill on your Novolin R prescription, you will need to see a board-certified doctor. To get started, book a virtual appointment with one of our top-rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take Novolin R?

    People who are not diagnosed with diabetes should not take Novolin R. You also should not take Novolin R if you are hypoglycemic or are allergic to insulin.

  • When should Novolin R be given?

    Novolin R should be taken about 30 minutes before a meal.

  • How do you take Novolin R insulin?

    Novolin R insulin is injected subcutaneously into a fatty area, such as the abdomen, buttocks, upper arm, or thigh.

  • How long is a vial of Novolin R good for?

    Once opened, Novolin R is good for six weeks. Afterwards, it should be thrown away, even if it is not completely finished.

  • What happens if I miss a dose of Novolin R?

    If you miss a dose, monitor your blood glucose closely, and take it as soon as you can. However, if it is almost time for your next dose, simply take the next dose as scheduled.

  • What happens if I take too much Novolin R?

    Taking too much Novolin R can be life-threatening, as it may cause hypoglycemia (low blood glucose levels). If you've taken too much Novolin R, seek emergency medical attention or call your local poison control center immediately.

3 simple steps to request your Novolin R prescription today 

Step 1

Book a Novolin R prescription request appointment.

Book a same-day appointment from anywhere.

Step 2

Talk to your clinician regarding your Novolin R prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Novolin R prescription.

We can send prescriptions to any local pharmacy.

Novolin R prescription pricing details

How pricing works

To get a new or refill on your Novolin R prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.