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Trulicity (dulaglutide) prescription available online

If you are suffering from type 2 diabetes mellitus, Trulicity can help. Get a new prescription or refill of Trulicity from a board-certified doctor online.*

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*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

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About Trulicity

Trulicity is an injectable diabetes medication that helps control blood sugar levels. Trulicity is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It can also help reduce the risk of major cardiovascular events, such as heart attack and stroke, in adults with type 2 diabetes and heart disease.

Trulicity is available only by prescription. It is available in a generic formulation as well as under different brand names, including dulaglutide. 

Trulicity may be prescribed as an injection. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Trulicity, it is important to use it daily, or as directed, in order for the medication to adequately treat and manage your medical issue.

Trulicity uses

Trulicity is approved by the FDA for the treatment of Type 2 Diabetes in conjunction with lifestyle changes and other medications.

Type 2 diabetes

Trulicity is FDA-approved as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It is not recommended for adults with type 1 diabetes or diabetic ketoacidosis.

Cardiovascular risk reduction

Trulicity is FDA-approved to reduce the risk of major cardiovascular events in adults with type 2 diabetes who have heart disease or multiple cardiovascular risk factors.

Trulicity side effects

The side effects associated with taking Trulicity are typically mild.

Trulicity has some side effects. They may include:

  • Low blood sugar

  • Nausea, vomiting, or stomach pain

  • Diarrhea

  • Decreased appetite

  • Injection-site reaction

  • Fatigue


Other side effects, which are less common but might be more severe, could include:

  • Severe pain in your upper stomach spreading to your back

  • Signs of kidney problems, such as changes in urination

  • Very rapid heartbeat


Tell your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. The use of Trulicity in children under age 18 is not recommended.

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How to take Trulicity

Your doctor will provide you with instructions on how to take your Trulicity prescription. Be sure to read your prescription label and follow the instructions. Call your doctor if you have any questions.

Trulicity can come in different doses, so be sure to follow the specific instructions on your prescription.

Use Trulicity on the same day each week at the same time of day. Inject Trulicity under the skin of your stomach, thigh, or upper arm. If you change your dosing day, allow at least three days to pass between doses. You can take your Trulicity pen with or without food.

What to avoid while taking Trulicity

Trulicity has many possible drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other prescription medicines or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Trulicity include:


Trulicity can slow digestion, and it may take longer for your body to absorb any medications taken orally.

Drinking alcohol with Trulicity may lead to adverse effects, such as low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia). Avoidance of alcohol consumption is recommended for all diabetics. Alcohol can have a significant negative impact on health and control of diabetes.

 

Medication alternatives to Trulicity

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other diabetes medications or blood sugar-lowering agents in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Trulicity prescription FAQs

How much does Trulicity cost?

Depending on your pharmacy, Trulicity subcutaneous solution (0.75 mg/0.5 mL) costs around $943 for 2 mL. Fortunately, generic brands, such as dulaglutide, offer an affordable alternative.

How can I refill my Trulicity prescription?

To refill your Trulicity prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

How long does it take for Trulicity to kick in?

It typically takes four weeks for Trulicity to affect your blood sugar levels. The maximum effect of Trulicity can be seen within 3–6 months.

Is it better to take Trulicity at night or in the morning?

You can take Trulicity at any time of day. Be sure to use Trulicity on the same day of the week.

Who should not take Trulicity?

Avoid taking Trulicity if you have certain medical conditions, such as:

  • Multiple endocrine neoplasia syndrome type 2 (MEN 2)

  • A family history of medullary thyroid carcinoma

  • Thyroid tumors, including thyroid cancer

  • Kidney problems or acute kidney injury

  • Vision problems related to diabetes (diabetic retinopathy)

  • Serious allergic reactions to diabetes medications

  • Severe stomach problems or intestinal disorder


Tell your healthcare provider if you're taking other diabetes medicines, such as insulin treatment, before starting Trulicity.

What happens if I miss a dose of Trulicity?

If you miss a dose of Trulicity, take the missed dose as soon as possible. Skip the missed dose if your next dose is due in less than three days. Avoid taking two doses of Trulicity in a 72-hour period.

What happens if I take too much Trulicity?

If you've taken too much Trulicity, seek medical advice promptly by calling your doctor or local poison control center. Trulicity can cause severe low blood sugar (hypoglycemia), which may require medical help.

When should you not take Trulicity?

Avoid taking Trulicity if you have a personal or family history of medullary thyroid carcinoma (MTC) or if you have multiple endocrine neoplasia syndrome type 2 (MEN 2). Seek medical advice promptly if you notice any signs of thyroid tumors, such as trouble swallowing.

3 simple steps to request your Trulicity prescription today

How It Works Step 1
Step 1

Book a Trulicity prescription request appointment.

Book a same day appointment from anywhere.
How It Works Step 2
Step 2

Talk to your medical provider regarding your Trulicity prescription.

Visit with a doctor on your smartphone or computer.
How It Works Step 3
Step 3

Pick up your Trulicity prescription.

We can send prescriptions to any local pharmacy.

Trulicity prescription pricing details

To get a new or refill on your Trulicity prescription, join our monthly membership and get discounted visits.

30 days of free membership

  • Same-day appointments 7 days a week
  • Unlimited messages with your Care Team
  • Prescription discount card to save up to 80%
  • Exclusive discounts on lab tests
  • Free memberships for your family
  • Cancel anytime

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Trulicity prescription resources

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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.