Most major insurance plans accepted
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your Humalog prescription today

Step 1
Book a Humalog prescription request appointment.
Book a same day appointment from anywhere.

Step 2
Talk to your medical provider regarding your Humalog prescription.
Visit with a doctor on your smartphone or computer.

Step 3
Pick up Humalog.
We can send prescriptions to any local pharmacy.
Humalog prescription pricing details
How pricing works
To get a new or refill on your Humalog prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Humalog prescription FAQs
How much does Humalog cost?
Depending on your pharmacy, Humalog costs around $530 for a five-pack of 3 mL Humalog U-100 KwikPens without health insurance. Visit the Lilly diabetes solution center for more information about pricing options. Fortunately, generic brands, such as insulin lispro, may offer an affordable alternative.
How can I refill my Humalog prescription?
To refill your insulin lispro (Humalog) prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.
Who should not take Humalog?
You should avoid taking Humalog if you have:
Low blood sugar levels (hypoglycemia)
A history of low blood sugar reactions
Allergic reactions to insulin products
How much Humalog can you take in a day?
The starting dose for Humalog is about four units or about 10% of your long-acting insulin dose. You should take Humalog at your largest meal of the day.
How long can Humalog be unrefrigerated?
Unopened Humalog vials should be refrigerated until you're ready to use them. Any unopened Humalog vials, cartridges, and prefilled pens should be discarded after 28 days when kept at room temperature.
How long does it take for Humalog to take effect?
A fast-acting insulin dose such as Humalog starts working about 15 minutes after injection to lower blood sugar levels.
What is the difference between insulin lispro protamine and insulin lispro?
Insulin lispro protamine is an intermediate-acting insulin, while insulin lispro is a fast-acting insulin.
About Humalog (insulin lispro)
Humalog is a fast-acting insulin dose that starts working about 15 minutes after injection. It helps control high blood sugar levels in adults and children with type 1 or type 2 diabetes.
Humalog moves sugar from the blood into other tissues where it's used for energy. It also stops the liver from producing blood sugar and slows the liver's production of glucose.
Humalog is available only by prescription. It's available in two different forms: Humalog and Humalog Mix (combination protamine and insulin lispro). It's available in a generic formulation under the name insulin lispro.
Humalog may be prescribed as an insulin dose injection. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed insulin lispro injection (Humalog), be sure to complete the full course unless your doctor specifically tells you to stop. If you don’t complete your prescription, Humalog may not fully treat your high blood sugar levels.
Humalog uses
There are several FDA-approved uses for insulin lispro injection (Humalog), but your healthcare provider may also prescribe it off-label to treat other medical conditions.
Your doctor may prescribe Humalog for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, talk with your doctor or pharmacist.
Diabetes mellitus
Humalog is FDA-approved to treat type 1 and type 2 debates. Humalog is typically used with intermediate-acting insulins or long-acting insulins. Fast-acting insulins can help cover insulin needs for meals eaten within 30 minutes of injection.
Humalog side effects
The side effects associated with taking Humalog are typically mild. Individuals taking insulin lispro (Humalog) report a variety of side effects, and side effects may vary from patient to patient.
The side effects of insulin lispro injection products may include:
Sudden weight gain
Low blood sugar levels
Low potassium
Other side effects, which are less common but might be more severe, could include:Hypokalemia (low blood potassium)
Hypoglycemia (severe low blood sugar)
Allergic reaction to insulin lispro products
Local amyloidosis at the injection site
Call your doctor or pharmacist if you notice any adverse effects or if you develop any new or concerning symptoms. Talk with your doctor if you experience insulin weight gain while taking Humalog. Humalog is FDA-approved in children over the age of 3 with type 1 diabetes.
How to take Humalog
Your pharmacist will provide you with instructions on how to take your Humalog prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Humalog is a rapid-acting insulin dose that works faster than human insulin. You can inject Humalog under the skin using a syringe and needle, injection pen, or insulin pump.
Your doctor may prescribe Humalog or Humalog Mix (protamine and insulin lispro) to manage blood sugar. Your doctor will show you how to properly use insulin lispro by yourself. Humalog is taken within a dose window of 15 minutes before or after a meal.
What to avoid while taking Humalog
Humalog has several drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other prescription medicines, herbal supplements, and over-the-counter medicines.
Humalog (insulin lispro) injection drug interactions may include:
Tell your doctor if you're taking oral diabetes medicines, such as rosiglitazone or pioglitazone. Taking certain diabetes medications while using insulin injections can increase your risk of severe heart problems.
It's safe to drink alcohol while taking insulin lispro injectable suspension. However, you should avoid alcohol if your diabetes is not well controlled.
Never share your insulin pump or injection supplies with another person, even if the needle has been changed.
Medication alternatives to Humalog
If your healthcare provider prefers to put you on another treatment, they may suggest other insulins, such as other rapid-acting insulin analogs. Here are some common doctor-recommended alternatives based on your health issue:
Type 1 diabetes
Humulin R (human recombinant) Novolin R (regular human insulin)Afrezza (regular human insulin)
Apidra (glulisine) Novolog (aspart)Type 2 diabetes