Invokamet (canagliflozin/ metformin) prescription available online

If you are suffering from type 2 diabetes, Invokamet (canagliflozin/ metformin) can help. Get a new prescription or refill of Invokamet from a board-certified doctor online*

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Helps lower blood sugar

Effective medication to treat type 2 diabetes*

Request Invokamet in as little as 15 minutes, with or without insurance*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Invokamet (canagliflozin and metformin) 

Invokamet is considered an SGLT2 inhibitor, which helps lower blood sugar by restoring the body's natural response to insulin. It also increases the removal of sugar from the kidneys, decreases how much sugar is produced in the liver, and decreases how much sugar the body takes in through the stomach and intestines.

Some conditions that Invokamet is known to treat include type 2 diabetes. Invokamet is available only by prescription. It is available in a generic formulation as well as under different brand names, including canagliflozin and metformin.

Invokamet may be prescribed as an extended-release tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Invokamet, be sure to complete the full course of the SGLT2 inhibitor unless your doctor specifically tells you to stop. If you don’t complete your prescription, the diabetes medication may not fully treat your type 2 diabetes. 

Invokamet uses

There are many FDA-approved uses for Invokamet, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your doctor may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online physician or pharmacist.

  • Type 2 diabetes mellitus

    Invokamet is FDA-approved to treat type 2 diabetes mellitus. Invokamet helps lower blood sugar, which can help prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

    Invokamet is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis.

  • End-stage kidney disease

    Invokamet may also be prescribed to reduce the risk of end-stage kidney disease and hospitalization or death in adults with type 2 diabetes who have kidney function problems.

Invokamet side effects

  • The side effects associated with taking Invokamet are typically mild. Most Invokamet side effects are associated with gastrointestinal discomfort. Invokamet has some common side effects. They may include:

    • Gas, stomach pain, or indigestion

    • Urinating more than usual

    • Headache or weakness

    If you experience stomach upset after taking your medication for several days, it’s important to contact your doctor right away as this can be a sign of something more serious such as metformin-associated lactic acidosis.

    Other side effects, which are less common but might be more severe, could include:

    • Little or no urination

    • High potassium levels (muscle weakness, chest pain, irregular heartbeat)

    • New pain, tenderness, or sores in your legs or feet

    You should talk to your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. It is not known whether Invokamet is safe and effective in children under 18.

How to take Invokamet

Your pharmacist will provide you with instructions on how to take your Invokamet prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Invokamet can come in different forms and doses, so be sure to follow the specific instructions on your prescription. When taking Invokamet XR, patients will generally take two pills once daily per a doctor’s prescription. If you're taking regular Invokamet, you'll be prescribed to take one pill twice daily or as directed by your doctor.

Invokamet and Invokamet XR both come in four different strengths, including:

  • 50 mg/500 mg

  • 150 mg/500 mg

  • 50 mg/1000 mg

  • 150 mg/1000 mg

What to avoid while taking Invokamet

Invokamet has 461 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Invokamet include:

  • Metformin

  • Gymnema

  • Digoxin

  • Rifampin

  • Ritonavir

  • Seizure medications

Ask your doctor for medical advice before drinking alcohol. Alcohol can exacerbate the effects of metformin on lactate metabolism, which can increase the risk of lactic acidosis. Excessive alcohol intake may also increase the risk of hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar) in patients with diabetes.

Medication alternatives to Invokamet

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other SGLT2 inhibitors or diabetes medications in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Invokamet prescription FAQs

  • How much does Invokamet cost?

    Depending on your pharmacy, Invokamet typically costs around $640 for a supply of sixty 150 mg/5000 mg tablets without insurance. Fortunately, generic alternatives, such as canagliflozin and metformin, may offer an affordable alternative. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Invokamet prescription?

    To refill your Invokamet prescription, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take Invokamet?

    To make sure Invokamet is safe for you, tell your doctor if you have:

    • Cardiovascular disease or heart failure

    • Diabetic foot ulcers

    • Circulation problems in your legs or feet

    • Liver or kidney disease

    • Low levels of vitamin B12

    • Urinary tract infections or other bladder infections

    • Peripheral vascular disease

  • What happens if I miss a dose of Invokamet?

    If you miss a dose of Invokamet, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Invokamet?

    If you've taken too much Invokamet, seek medical attention immediately or contact your local poison control center. Taking too much Invokamet can lead to extremely low blood sugar (severe hypoglycemia).

  • How does Invokamet work?

    Invokamet combines canagliflozin and metformin to improve glycemic control and support the body's response to natural insulin.

  • What are the benefits of Invokamet?

    Invokamet helps control blood sugar levels in adults with type 2 diabetes mellitus, which can prevent kidney damage, nerve-related issues, and blindness.

  • Is Invokamet the same as metformin?

    No, Invokamet is not the same as metformin. Both medications are used to treat type 2 diabetes by lowering blood sugar. However, Invokamet increases the amount of sugar passed out of the body through urine, while metformin reduces the absorption of sugar from the intestines.

  • What is Invokamet used to treat?

    Invokamet is used to treat type 2 diabetes mellitus. It can also reduce the risk of end-stage kidney disease and cardiovascular death in adults with type 2 diabetes mellitus.

  • What type of drug is Invokamet?

    Invokamet is a sodium-glucose cotransporter-2 (SGLT2) inhibitor.

3 simple steps to request your Invokamet prescription today 

Step 1

Book an Invokamet prescription request appointment.

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Step 2

Talk to your medical provider regarding your Invokamet prescription.

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Step 3

Pick up your Invokamet prescription.

We can send prescriptions to any local pharmacy.

Invokamet prescription pricing details

How pricing works

To get a new or refill on your Invokamet prescription, join our monthly membership and get discounted visits.

Paying with insurance



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30 days of free membership

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  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.


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