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Glyxambi (empagliflozin/linagliptin)
Chronic Care Diabetes Glyxambi
Chronic Care Diabetes Glyxambi

Glyxambi (Empagliflozin/Linagliptin) prescription available

If you are suffering from type 2 diabetes mellitus, Glyxambi can help. Get a new prescription or refill of Glyxambi today from a board-certified doctor online.*

Treat type 2 diabetes mellitus in adults Recommended to take at the same time each day Not effective in treating type 1 diabetes mellitus
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*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.
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About Glyxambi

Glyxambi is a combination of empagliflozin and linagliptin, which are oral diabetes medications that help control blood sugar. Empagliflozin helps the kidneys get rid of glucose from your bloodstream, while linagliptin regulates insulin produced by your body after eating.

 

Glyxambi is used to treat type 2 diabetes mellitus. It can also lower the risk of cardiovascular death from heart attack, stroke, or heart failure in adults with type 2 diabetes and established cardiovascular disease. Glyxambi is available only by prescription. It is available in a generic formulation as well as under different brand names, including empagliflozin and linagliptin. 

 

Glyxambi may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

Glyxambi uses

There are several FDA-approved uses for Glyxambi.

 

If you have questions about why a medication is prescribed, ask your online doctor

Type 2 diabetes mellitus

Glyxambi is FDA-approved to improve glycemic control in adults with type 2 diabetes when treatment with both empagliflozin and linagliptin is appropriate. Glyxambi can be part of a comprehensive treatment plan that also includes diet and exercise.



Glyxambi can also help lower the risk of cardiovascular death from heart attack, stroke, or heart failure in adults with type 2 diabetes and established cardiovascular disease.



Glyxambi is not effective in treating type 1 diabetes mellitus or diabetic ketoacidosis.

Glyxambi side effects

The side effects associated with taking Glyxambi are typically mild. Most Glyxambi side effects are associated with urinary tract infections. Glyxambi has some common side effects. They may include:

UTIs Upper respiratory tract infections Headache Vaginal yeast infection

Other side effects, which are less common but might be more severe, could include:

Dehydration
Fast heartbeat
Rapid breathing

Tell your doctor if you notice any adverse effects or develop any other new or concerning symptoms. Glyxambi (empagliflozin/linagliptin) is not approved for blood sugar control in children under 18.

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How to take Glyxambi

Your online doctor will provide you with instructions on how to take your Glyxambi prescription. Be sure to read your prescription label and follow the instructions. Call your doctor if you have any questions.

 

Glyxambi can come in different forms and doses, so be sure to follow the specific instructions on your prescription.

 

Your doctor will regularly monitor your blood sugar levels to ensure Glyxambi is safe. Be careful when getting up from a sitting or lying position or you may feel dizzy.

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What to avoid while taking Glyxambi

Glyxambi has many drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other drugs or supplements, as well as over-the-counter medicines. 

Possible drug interactions with Glyxambi include:



Drinking alcohol while taking Glyxambi can increase the risk of low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia), depending on how much you drink. Talk to your doctor before you drink alcohol.

Medication alternatives to Glyxambi

If your healthcare provider prefers to put you on another treatment, they may suggest another diabetes medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Type 2 diabetes mellitus

Invokamet (canagliflozin and metformin)
Synjardy (empagliflozin and metformin)
Xigduo XR (dapagliflozin and extended-release metformin)

Glyxambi prescription FAQs

How much does Glyxambi cost?

Depending on your pharmacy, Glyxambi costs around $610 for thirty 10 mg/5 mg tablets without insurance. Fortunately, generic brands, such as empagliflozin and linagliptin, offer an affordable alternative.

How can I refill my Glyxambi prescription?

To refill your Glyxambi prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your medical history, your doctor can send an electronic prescription to your local pharmacy.

Who should not take Glyxambi?

Avoid taking Glyxambi if you have certain medical conditions, such as:

  • Serious allergic reaction to empagliflozin or linagliptin

  • Diabetic ketoacidosis or type 1 diabetes

  • Severe kidney problems, such as end-stage renal disease

What is the best time to take Glyxambi?

The best time to take Glyxambi is in the morning, with or without food. However, you can safely take Glyxambi at any time of the day.

Does Glyxambi cause kidney damage?

In rare cases, Glyxambi can cause kidney problems. Kidney damage is more likely to occur if you already have kidney problems, heart failure, or take certain medications for blood pressure.

Can you take Glyxambi at night?

Glyxambi can be taken at any time of the day, with or without food. Make sure to take Glyxambi at the same time each day.

What happens if I miss a dose of Glyxambi?

If you miss a dose of Glyxambi, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

What happens if I take too much Glyxambi?

If you've taken too much Glyxambi, seek emergency medical attention or contact your local poison control center.

 

3 simple steps to request your Glyxambi prescription today

How It Works Step 1
Step 1

Book a Glyxambi prescription request appointment.

Book a same day appointment from anywhere.
How It Works Step 2
Step 2

Talk to your medical provider regarding your Glyxambi prescription.

Visit with a doctor on your smartphone or computer.
How It Works Step 3
Step 3

Pick up your Glyxambi prescription.

We can send prescriptions to any local pharmacy.

Glyxambi prescription pricing details

To get a new or refill on your Glyxambi prescription, join our monthly membership and get discounted visits.

30 days of free membership

  • Same-day appointments 7 days a week
  • Unlimited messages with your Care Team
  • Prescription discount card to save up to 80%
  • Exclusive discounts on lab tests
  • Free memberships for your family
  • Cancel anytime

Paying with insurance

Membership

$19.99

First month free

+

Visits

Copay

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

We accept these insurance plans and many more:


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Paying without insurance

Membership

$19.99

First month free

+

Visits

$129

Visit price without insurance

Initial visits are $129.
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*If we're unable to treat you, we'll provide a full refund. Please note that any medication or lab work costs are not included. Please refer to our refund policy for additional information.

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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.