Novolin N (NPH insulin) prescription available online 

If you are suffering from diabetes mellitus, Novolin N can help. Get a new prescription or refill of Novolin N from a board-certified doctor online.*

Book an appointment

Take control of your blood sugar

Available as an injection or suspension

Complete the full course of medication for best results

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Novolin N (NPH insulin)

Novolin N is considered a man-made intermediate-acting insulin drug, which functions by lowering levels of blood glucose (sugar). Like other human insulin medications, Novolin N is not effective for the treatment of diabetic ketoacidosis.

Novolin N is used to treat diabetes mellitus. Novolin N is available only by prescription. It is available in a generic formulation as well as under different brand names, including neutral protamine Hagedorn insulin (NPH insulin).

Novolin N may be prescribed as an injection or suspension. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Novolin N, be sure to complete the full course of the human insulin unless your doctor specifically tells you to stop. If you don’t complete your prescription, NPH insulin may not fully treat your diabetes mellitus.

Novolin N uses

There are several FDA-approved uses for Novolin N, but it may also be used off-label to treat other conditions. Your online healthcare provider may prescribe it for any of the following common reasons. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Diabetes mellitus

    Novolin N is FDA-approved for the treatment of adult and pediatric patients with diabetes mellitus. As an intermediate-acting insulin, Novolin N promotes blood glucose control by lowering blood sugar.

Novolin N side effects

  • The side effects associated with taking Novolin N are typically mild. Most Novolin N side effects are associated with low blood sugar. Novolin N has some common side effects. They may include:

    • Low blood sugar

    • Weight gain, or swelling in the hands or feet

    • Itching or mild skin rash

    Other side effects, which are less common but might be more severe, could include:

    • Fluid retention (edema)

    • Serious allergic reaction

    • Low potassium levels

    You should call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. The use of Novolin N is safe and effective for the pediatric population.

How to take Novolin N

Your pharmacist will provide you with instructions on how to take your Novolin N prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Novolin N can come in different forms and doses, so be sure to follow the specific instructions on your prescription. Your healthcare provider will work with you to choose a proper dose to treat high blood sugar. Insulin dose adjustment may be required.

Novolin N is injected under the skin. Your healthcare provider can show you how to properly inject your insulin dose by yourself. Avoid injecting Novolin N into damaged skin, and use a different injection site each time you give yourself an insulin dose.

What to avoid while taking Novolin N

Novolin N has 378 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Novolin N include:

  • Novolin R (insulin regular)

  • Gabapentin

  • Furosemide

Ask your doctor for medical advice before drinking alcohol. Alcohol can lead to an increased risk of hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar) depending on how much you drink.

Medication alternatives to Novolin N

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another human insulin drug or diabetes medicine in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Novolin N prescription FAQs

  • How much does Novolin N cost?

    Depending on your pharmacy, Novolin N costs around $155 for a supply of 10 mL without insurance. Fortunately, generic brands, such as NPH insulin, may offer an affordable alternative.

  • How can I refill my Novolin N prescription?

    Novolin N is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take Novolin N?

    To make sure Novolin N is safe for you, tell your doctor if you have:

    • Liver or kidney disease

    • Diabetic ketoacidosis

    • Low potassium levels

    • Low blood sugar

    • Allergic reactions to insulin

  • How long does Novolin N stay in your system?

    Novolin N can stay in your system for up to 24 hours.

  • How long is Novolin N good out of the fridge?

    Opened vials of Novolin N can be stored at room temperature for 42 days. Unopened vials of Novolin N can be stored at room temperature for 28 days.

  • What happens if Novolin N is taken after food?

    Taking Novolin N after eating can increase your risk of low blood sugar (hypoglycemia). To treat low blood sugar quickly, drink fruit juice or non-diet soda.

  • What happens if you shake Novolin N?

    Shaking a vial of Novolin N can cause insulin particles to stick to the vial, which can reduce the effectiveness of human insulin.

  • What happens if I miss a dose of Novolin N?

    If you miss a dose of NPH insulin, take the missed dose as soon as you remember. Skip the missed dose if it’s almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Novolin N?

    If you've taken too much Novolin N, seek emergency medical attention or contact your local poison control center. An insulin overdose can cause life-threatening severe hypoglycemia (low blood sugar).

3 simple steps to request your Novolin N prescription today 

Step 1: Book an appointment

Step 1

Book a Novolin N prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Novolin N prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Novolin N prescription.

We can send prescriptions to any local pharmacy.

Novolin N prescription pricing details

How pricing works

To get a new or refill on your Novolin N prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.