Scopolamine transdermal patch prescription available online

If you suffer from nausea and vomiting, scopolamine can help. Get a new prescription or refill of Scopolamine today from a board-certified doctor online.*

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Treats motion sickness and post-operative nausea

Available as a transdermal patch

Follow specific prescription instructions for effectiveness

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About scopolamine

Scopolamine is considered an anticholinergic antiemetic, which reduces the secretions of certain organs, including the stomach and intestines, to prevent nausea and vomiting.

Scopolamine can help reduce nausea and vomiting associated with motion sickness or from anesthesia given during surgery. Scopolamine is available only by prescription. It is available in a generic formulation as well as under different brand names, including Transderm Scop.

Scopolamine may be prescribed as a transdermal patch. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed scopolamine, be sure to complete the full course of the anticholinergic unless your doctor specifically tells you to stop. If you don’t complete your prescription, the anticholinergic may not fully treat your nausea and vomiting.

Scopolamine uses

There are several FDA-approved uses for scopolamine, but it may also be used off-label to treat other conditions. Your online health care professional may prescribe it for any of the following common reasons. It’s also possible that your health care professional may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Motion sickness

    The scopolamine patch is FDA-approved to treat nausea and vomiting associated with motion sickness.

  • Post-operative nausea and vomiting

    The scopolamine patch is FDA-approved to treat post-operative nausea and vomiting (PONV) associated with recovery from anesthesia and/or opiate analgesia and surgery.

Scopolamine side effects

  • The side effects associated with taking scopolamine are typically mild. Most Scopolamine side effects are associated with dry mouth. Scopolamine has some common side effects. They may include:

    • Dry mouth

    • Blurred vision

    • Drowsiness or dizziness

    Other side effects, which are less common but might be more severe, could include:

    • Severe dizziness

    • Eye pain or redness

    • Difficulty urinating

    You should call your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of scopolamine in young children under age 18 is not advised.

How to take scopolamine

Your pharmacist will provide you with instructions on how to take your scopolamine prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Scopolamine can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The transdermal patch should be applied to a hairless area of skin just behind the ear. In some cases, if directed by your doctor, health care professional may apply the transdermal patch before your surgery.

To prevent nausea and vomiting after surgery, the transdermal patch is usually applied in the evening before surgery. Keep wearing the transdermal patch for 24 hours after your surgery. Then, remove it and throw it away.

Avoid wearing more than one patch at a time. You can wear the transdermal patch for up to three days. If the patch falls off, replace it with a new patch.

What to avoid while taking scopolamine

Scopolamine has 342 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as other drugs. 

Possible drug interactions with the scopolamine patch include:

  • Medications used to treat depression, anxiety disorders, and other mental illnesses

  • Cold or allergy medicine, including Benadryl

  • Medicine used to treat Parkinson's disease

  • Bronchodilator asthma medication

  • Other medications used to treat stomach problems or motion sickness

Talk to your doctor before drinking alcohol. Alcohol may increase drowsiness, dizziness, and other adverse effects. Avoid exceeding recommended dosages, and make sure to avoid activities that require mental alertness.

Medication alternatives to scopolamine

If your healthcare provider prefers to put you on another treatment, they may suggest another antiemetic or anti-nausea medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • Motion sickness

    Dramamine (dimenhydrinate)


    Phenadoz (promethazine)
  • Post-operative nausea and vomiting

    Maxidex (dexamethasone)



Scopolamine prescription FAQs

  • How much does scopolamine cost?

    Depending on your pharmacy, the extended-release scopolamine patch costs around $31 for four patches without insurance. Scopolamine is a generic brand, and brand names may cost more.

  • How can I refill my scopolamine prescription?

    To refill your scopolamine prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take scopolamine?

    To make sure the scopolamine patch is safe for you, tell your doctor if you have:

    • Glaucoma

    • Liver or kidney disease

    • A history of seizures

    • Mental illness

    • Severe preeclampsia

    • Urination problems, such as urinary retention

    • Intestinal obstruction

  • How long is scopolamine in your system?

    The effects of the scopolamine patch wear off about nine hours after the patch is removed. However, the effects of scopolamine can stay in your system for days or weeks after removing the patch.

  • How long does scopolamine last after you take it off?

    The effects of the scopolamine patch last for around nine hours after removing the patch.

  • How far in advance should you put on a scopolamine patch?

    To prevent nausea and vomiting associated with motion sickness, apply one patch behind the ear at least four hours in advance. For post-operative nausea and vomiting, your health care professional may recommend applying the patch behind other ear the night before surgery.

  • What happens if I miss a dose of scopolamine?

    Since the transdermal patch is used when needed, you may not be on a regular dosing schedule. Skip any missed dose if it's almost time for the next dose. Use only one patch at a time.

  • What happens if I take too much scopolamine?

    If you've taken too much scopolamine, call your doctor immediately or contact your local poison control center. If you experience overdose symptoms, such as severe drowsiness, vision problems, or hallucinations, seek emergency medical help.

  • Can I buy a scopolamine patch over the counter?

    Scopolamine patches are available only as prescription medications. Scopolamine can have side effects, including drowsiness, dry mouth, blurred vision, and dizziness. Your doctor will determine if you are good candidate for scopolamine and prescribe the appropriate dosage to minimize potential side effects.

    Depending on your personal health history, a doctor might recommend alternative medications for motion sickness, such as meclizine (Dramamine) or dimenhydrinate (Bonine), which are often available over-the-counter. These medications might cause fewer side effects for some people.

    In some cases, nausea and vomiting can be symptoms of underlying medical conditions. Your doctor can diagnose the cause of your nausea and recommend the most appropriate treatment plan.

3 simple steps to request your scopolamine prescription today

Step 1

Book a scopolamine prescription appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your scopolamine prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your scopolamine prescription.

We can send prescriptions to any local pharmacy.

 Scopolamine prescription pricing details

How pricing works

To get a new or refill on your Scopolamine prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.