We accept these insurance plans and many more!
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your Medrol prescription today

Step 1
Book a Medrol prescription request appointment.
Book a same day appointment from anywhere.

Step 2
Talk to your medical provider regarding your Medrol prescription.
Visit with a doctor on your smartphone or computer.

Step 3
Pick up your Medrol prescription.
We can send prescriptions to any local pharmacy.
Medrol prescription pricing details
How pricing works
To get a new or refill on your Medrol prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Medrol prescription FAQs
How much does Medrol cost?
Depending on your pharmacy, Medrol costs around $16 for twelve 4 mg tablets without insurance. Fortunately, Medrol generic (methylprednisolone) offers an affordable alternative.
How can I refill my Medrol prescription?
To refill your Medrol prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.
What should you avoid while taking methylprednisolone?
Avoid consuming grapefruit and grapefruit juice while taking Medrol. Ask your doctor for medical advice before drinking alcohol, as drinking alcohol with Medrol may increase your risk of stomach bleeding.
Medrol can suppress your immune system, which can lead to an increased risk of infections and illness. Avoid spending time around people who are sick or have an infectionCan I drink coffee while taking Medrol?
Stimulants, such as coffee, may worsen the sleep-related side effects of Medrol, including insomnia. Stop drinking coffee if you experience adverse effects.
How many days Medrol can be taken?
Medrol is typically taken for 10–12 days. The long-term use of corticosteroids can increase your risk of side effects, such as withdrawal symptoms.
How long does Medrol take to reduce inflammation?
Medrol starts working within one hour to reduce inflammation.
Who should not take Medrol?
Avoid taking Medrol if you have certain medical conditions, such as:
Allergic reactions to methylprednisolone
Thyroid conditions
High blood pressure
Depression or other mental illness
Osteoporosis
Stomach ulcers
Liver disease, especially cirrhosis
Herpes infection of the eyes
What happens if I miss a dose of Medrol?
If you miss a dose of Medrol, call your doctor for instructions on taking the missed dose. Avoid taking two doses at the same time to make up for a missed dose.
What happens if I take too much Medrol?
If you've taken too much Medrol, seek emergency medical attention or contact your local poison control center.
About Medrol
Medrol is considered a corticosteroid, which blocks the release of natural substances in the body that cause inflammation.
Medrol treats inflammatory conditions, including endocrine disorders, severe allergies, lupus, and rheumatoid arthritis. Medrol is available only by prescription. It is available in a generic formulation under different brand names, including methylprednisolone.
Medrol may be prescribed as an oral tablet, injection, or compounding powder. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you are prescribed Medrol, complete the entire course of the corticosteroid therapy unless your healthcare professional specifically tells you to stop. If you don’t complete your prescription, corticosteroid therapy may not fully treat your inflammation.
Medrol uses
There are several FDA-approved uses for Medrol, but it may also be used off-label to treat other conditions. Your online healthcare professional may prescribe it for any of the following common reasons.
It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.
Endocrine disorders
Medrol is FDA-approved to treat endocrine disorders, including congenital adrenal hyperplasia, thyroiditis, and hypercalcemia associated with cancer.
Rheumatic disorders
Medrol is FDA-approved to treat rheumatic disorders, including rheumatoid arthritis, ankylosing spondylitis, acute and subacute bursitis, and synovitis of osteoarthritis
Dermatologic conditions
Medrol is FDA-approved to treat dermatologic conditions, including bullous dermatitis, Steven-Johnson syndrome, and severe psoriasis.
Gastrointestinal disorders
Medrol is FDA-approved to treat inflammation associated with gastrointestinal conditions, including ulcerative colitis and regional enteritis.
Multiple sclerosis
Medrol is FDA-approved to treat acute exacerbations of multiple sclerosis.
Medrol side effects
The side effects associated with taking Medrol are typically mild. Most Medrol side effects are associated with fluid retention. Medrol has some common side effects. They may include:
Fluid retention
Mild muscle cramps or weakness
Stomach discomfort or bloating
Other side effects, which are less common but might be more severe, could include:Shortness of breath
Blurred vision
Severe depression or mood swings
Rapid weight gain
Tell your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. Medrol may be prescribed to young children under the age of 12 with an adjusted dose.
How to take Medrol
Your pharmacist will provide you with instructions on how to take your Medrol prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Medrol can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The typical starting dose can range from 4 mg to 48 mg taken daily depending on the medical condition being treated.
Your healthcare professional may adjust your dose if you're facing unusual stress, such as a serious illness or infection, or if you have a medical emergency. Ask your doctor for medical advice about adjusting your dose.
Tell your doctor and other healthcare professionals that you're taking Medrol. Medrol may affect the results of certain medical tests.
What to avoid while taking Medrol
Medrol has 540 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other drugs or supplements, as well as other medications.
Possible drug interactions with Medrol include:
Benadryl (diphenhydramine)
Limit your consumption of grapefruit and grapefruit juice while taking Medrol. Ask your doctor for medical advice before drinking alcohol, as drinking alcohol with Medrol may increase your risk of stomach bleeding.
Medrol can suppress your immune system, which can lead to an increased risk of infections and illness. Avoid spending time around people who are sick.
Medication alternatives to Medrol
If your healthcare provider prefers to put you on another treatment, they may suggest another corticosteroid or anti-inflammatory medicine in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
Endocrine disorders
Rheumatic disorders
Dermatologic conditions
Gastrointestinal disorders
Omnipred (prednisolone)
Entocort (budesonide)
Azulfidine (sulfasalazine)
Multiple sclerosis