Biktarvy prescription available online 

If you are suffering from HIV, Biktarvy can help. Get a refill of Biktarvy from a board-certified primary care doctor online.*

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FDA-approved to treat HIV

Quick and secure Biktarvy prescription*

Accessible medications for HIV treatment

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card. Please note that the management of HIV usually requires ongoing care with a specialist. At this time, PlushCare does not offer chronic HIV management. Our primary care physicians can refill some of these medications as emergency short-term prescriptions or bridge for patients that are stable with their current regimen and until the patient is able to see their specialist. 

About Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide)

Biktarvy is a three-drug combination of bictegravir, emtricitabine, and tenofovir alafenamide, which prevents human immunodeficiency virus (HIV) from multiplying in your body.

Biktarvy is used to treat HIV infection. Biktarvy is available only by prescription. It is available in a generic formulation under different brand names, including bictegravir, emtricitabine, and tenofovir alafenamide.

Biktarvy may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Biktarvy, complete the entire nucleoside reverse transcriptase inhibitor course unless your doctor specifically tells you to stop. If you don’t complete your prescription, the antiviral medication may not fully treat your HIV infection.

Biktarvy uses

There is one FDA-approved use for Biktarvy, but it may also be used off-label to treat other conditions. Healthcare professionals may prescribe it for any of the following common reasons.

It’s also possible that your healthcare professional may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • HIV infection

    Biktarvy is FDA-approved to treat HIV in adult and pediatric patients weighing at least 31 pounds who have no antiretroviral therapy treatment history or to replace the current antiretroviral therapy regime in those who are virologically suppressed with no history of treatment failure.

    Biktarvy is a three-drug combination of bictegravir, a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), and emtricitabine and tenofovir alafenamide, both HIV-1 nucleoside reverse transcriptase inhibitor drugs.

Biktarvy side effects

  • The side effects associated with taking Biktarvy are typically mild. Most Biktarvy side effects are associated with gastrointestinal discomfort. Biktarvy has some common side effects. They may include:

    • Nausea, stomach pain, and vomiting

    • Diarrhea

    • Headache

    Other side effects, which are less common but might be more severe, could include:

    • Signs of a new infection

    • Difficulty speaking or swallowing

    • Severe drowsiness

    You should call your doctor if you notice any adverse reactions, or if you develop any other new or concerning symptoms. Biktarvy affects your immune system, which may cause certain side effects weeks or months after you've finished Biktarvy therapy.

    Biktarvy is approved to treat HIV infection in pediatric patients weighing above 31 pounds.

How to take Biktarvy

Your pharmacist will provide you with instructions on how to take your Biktarvy prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Biktarvy can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The typical daily dose for adults is bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg orally.

What to avoid while taking Biktarvy

Biktarvy has many drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Biktarvy include:

  • Dofetilide

  • Rifampin

  • Klonopin (clonazepam)

  • Glucophage (metformin)

  • Other antivirals that contain emtricitabine or tenofovir

Certain antacids, laxatives, and prescription drugs may make Biktarvy less effective when taken at the same time. Take your daily dose of Biktarvy on an empty stomach at least two hours before taking any other medications.

Talk to your doctor before drinking alcohol. People with HIV infection may be taking Biktarvy or other antiretroviral therapy and are often advised not to drink alcohol.

Medication alternatives to Biktarvy

If your healthcare provider prefers to put you on another treatment altogether, they may suggest a nucleotide reverse transcriptase inhibitor or antiretroviral therapy in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • HIV infection

    • Juluca 

    • Dovato 

    • Prezcobix 

    • Symtuza 

Biktarvy prescription FAQs

  • How much does Biktarvy cost?

    Depending on your pharmacy, Biktarvy costs around $3,784 for thirty 50 mg/200 mg/25 mg tablets without insurance.

  • How can I refill my Biktarvy prescription?

    To refill your Biktarvy prescription, book a virtual appointment with one of our top rated board-certified doctors. Your doctor will review your symptoms and medical history. After completing any necessary medical and lab appointments, your doctor can send an electronic prescription to your local pharmacy if you qualify.

  • What is Biktarvy used for?

    Biktarvy is used to treat HIV infection in adults and children.

  • Why does Biktarvy work so well?

    Biktarvy has a high barrier to resistance and fewer drug interactions than most HIV medications, making it a treatment of choice for many healthcare professionals.

  • Is Biktarvy a high risk medication?

    For some patients, Biktarvy may increase the risk of renal impairment-related reactions. Biktarvy can cause life-threatening side effects, including:

    • Lactic acidosis

    • Liver problems

    • New or worsening kidney problems

    • Drug interactions

    Talk to your doctor to make sure Biktarvy is safe for you.

  • What is the best time of day to take Biktarvy?

    Biktarvy should be taken at least two hours before taking nutritional supplements that contain magnesium, aluminum, or iron. Your doctor may recommend taking Biktarvy in the morning before your other medications.

  • Who should not take Biktarvy?

    Avoid taking Biktarvy if you have certain medical conditions, such as:

    • Liver disease

    • Kidney disease

    • Other autoimmune disorders

    • Severe hepatic impairment

    Patients with hepatitis B and HIV infection may experience severe acute exacerbations of their hepatitis B after stopping Biktarvy therapy. Tell your doctor if you're taking any other antiviral medications before starting Biktarvy. 

  • What happens if I miss a dose of Biktarvy?

    If you miss a dose of Biktarvy, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Biktarvy?

    If you've taken too much Biktarvy, seek emergency medical attention or contact your local poison control center.

3 simple steps to request your Biktarvy prescription today

Step 1: Book an appointment

Step 1

Book a Biktarvy prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Biktarvy prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up Biktarvy.

We can send prescriptions to any local pharmacy.

How to talk to your doctor about HIV treatment: helpful questions to ask

During your telemedicine visit, it's important to feel empowered to ask all your questions about your HIV treatment plan. At PlushCare, we prioritize open communication and ensuring you have the information you need to manage your health effectively. Here are some questions to get your conversation started:

  • Are there any alternative treatment options if this one doesn’t work for me?

  • What should I do if I miss a dose?

  • Are there certain foods, drinks, or substances I should avoid during treatment?

  • What is the best way to track my progress and treatment?

  • How often will I need to have blood tests to monitor my HIV?

  • Can you provide me with any resources or support systems that might help me manage my medications long-term?

  • Is there a possibility that I will become resistant to treatment, and are there other treatment options available?

  • Do you have any recommendations for disclosing my HIV status to my partner/future partners?

  • I’m interested in having a family. What considerations are there for people with HIV who want to have children?

  • Where can I learn about updates on a cure for HIV?

Biktarvy prescription pricing details

How pricing works

To get a new or refill on your Biktarvy prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.