Z-Pack (azithromycin) prescription available online

If you are suffering from a bacterial infection, Z-Pack (azithromycin) can help. Get a new prescription or refill of azithromycin today from a board-certified doctor online.

Book an appointment

Medication services available for adults and kids (3+)

Top quality, board-certified doctors

Insurance accepted, but not required

*Prescriptions provided at the doctor’s discretion

Most major insurance plans accepted

Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.

Don’t see your provider listed? Email [email protected]  or call  (888) 564-4454  to talk to a PlushCare specialist.

3 simple steps to request your Azithromycin prescription today

Step 1: Book an appointment

Step 1

Book a Z-Pack prescription request appointment.

You can book a same-day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Z-Pack prescription.

Then, you can visit a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Z-Pack prescription.

We can send prescriptions to any local pharmacy.

Z-Pack (azithromycin) prescription pricing details

How pricing works

To get a new or refill on your azithromycin prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free

First visit


For all visits

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free

First visit


Repeats only $99

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129 and follow-ups are only $99 for active members.

Book an appointment

If we're unable to treat you, we'll provide a full refund.

Z-Pack (azithromycin) prescription FAQs

  • How much does Z-Pack (azithromycin) cost?

    The average price for azithromycin is 36 dollars which break down to $6 per pill. This cost will fluctuate based on the pharmacy and insurance.

  • How can I refill my Z-Pack (azithromycin) prescription?

    Your doctor or pharmacist can send Azithromycin to any local pharmacy. Some common locations include CVS, Walmart, Rite Aid, and Walgreens.

  • What time of day should Z-Pack (azithromycin) be taken?

    Take azithromycin at the same time each day. Morning is recommended, as some users have trouble sleeping after taking azithromycin. When taking azithromycin capsules, take them at least 1 hour before food or 2 hours after eating.

  • When should you not take Z-Pack?

    You should not take azithromycin if you take any drug which interacts with azithromycin, including nelfinavir or warfarin, as the risk of adverse side effects is more significant. In addition, specific drug interactions may occur with other drugs, so always tell your doctor or pharmacist if you experience any unusual tiredness or severe dizziness.

  • What should I check before taking Z-Pack (azithromycin)?

    Observe for signs and symptoms of anaphylaxis as this can be a sign of an allergic reaction which can be severe in some patients.

  • What happens if I miss a dose of Z-Pack (azithromycin)?

    Take the missed dose as soon as possible, but skip the missed dose if it is near your current dosage time.

  • What happens if I take too much Z-Pack (azithromycin)?

    Taking too much azithromycin could cause irregular heart rhythm or liver damage. If you consume too much azithromycin, you should call your doctor, contact your local Poison Control Center, or seek emergency medical attention immediately.

About Z-Pack (azithromycin)

Azithromycin is considered one of the macrolide antibiotics which stops bacteria's growth. Like any antibiotic, you can only use this medication for bacterial infections. It is ineffective against viral infections because it will not treat the cold or flu.

Some conditions that azithromycin is known to treat include infections such as bronchitis, pneumonia, ears, lungs, and other organs, respiratory infections, skin infections, sexually transmitted diseases, bacterial inflammation, and middle-ear infections in children. Azithromycin is available only by prescription. It is available in a generic formulation under different brand names, including Zithromax, Zithromax Z-Pak, Zmax, AzaSite, and Zithromax TRI-PAK.

Azithromycin may be prescribed as oral tablets, liquids, injections, and intravenous drips. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage you are prescribed.

If you are prescribed azithromycin, be sure to complete the course of the antibiotic unless your doctor specifically tells you to stop. 

The antibiotic may only fully treat your infection if you complete your prescription. 

Z-Pack (azithromycin) uses

There are 8 FDA-approved uses for azithromycin, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.

  • Bronchitis

    Acute bacterial exacerbations of chronic bronchitis in adults.

  • Sinus Infections

    Acute bacterial sinusitis in adults

  • Skin Infections

    Uncomplicated skin and skin structure infections in adults

  • Inflammation of the Urethra

    Urethritis is an STI in adults

  • Genital herpes

    Genital ulcer disease in men

  • Middle Ear Infection (children)

    Acute otitis media in pediatric patients

  • Pneumonia

    Community-acquired pneumonia in adults and pediatric patients

  • Strep Throat

    Pharyngitis/tonsillitis in adults and pediatric patients

Z-Pack (azithromycin) side effects

  • The side effects associated with taking azithromycin are typically mild. Most azithromycin side effects are associated with gastrointestinal discomfort or allergic reactions. Azithromycin has some common side effects. They may include:

    Other side effects, which are less common but might be more severe, could include:

    • Severe allergic reaction

    • Liver injury

    • Diarrhea associated with antibiotic-resistant bacteria

    • Fast or pounding heartbeats

    • Sudden cardiac death

    • Severe dizziness

    • Severe intestinal conditions

    You should call your doctor if you notice any of these side effects or develop other new or concerning symptoms. The side effects are rarely fatal, but it is always best to tell your doctor if any conditions arise. The use of azithromycin in young children six months and older is approved.

How to take Z-Pack (azithromycin) safely

Your pharmacist will provide you with instructions on how to take your azithromycin prescription.

Be sure to read your prescription label and follow the instructions. Then, call your doctor or pharmacy if you have any questions.

Azithromycin can come in different forms and doses, so follow the specific instructions on your prescription. It is typically prescribed as a five-day pill regimen with a dose of 500 mg (2 tablets of 250 mg) on the first day and 250 mg for the remaining four days.

What to avoid while taking Z-Pack (azithromycin) tablets

Azithromycin has 333 possible drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.

Avoiding excessive sunlight exposure when taking azithromycin is essential as it can make you sunburn more easily.

Ask your doctor or pharmacist if consuming alcohol while taking azithromycin is acceptable.

There are no documented interactions between azithromycin and alcohol. However, drinking more alcohol is not recommended when fighting an infection because it may hinder the body’s ability to fight the disease, lead to dehydration, interrupt sleep, and worsen common side effects such as nausea, diarrhea, vomiting, and abdominal pain. It can also decrease effectiveness.

Avoid taking azithromycin if you have a specific muscle disease.

Do not take azithromycin if you take Nelfinavir. This drug can increase the amount of azithromycin in the blood. If you’re concerned about this interaction, tell your doctor to check for liver abnormalities and hearing impairment.

Do not take azithromycin if you take warfarin. Taking warfarin with azithromycin increases the blood thinning effect.

Tell your doctor or pharmacist about your medical history and other drugs you are taking before taking azithromycin.

Medication alternatives to Z-Pack (azithromycin)

If your healthcare provider prefers to put you on another treatment, they may suggest another macrolide antibiotic or a bacterial antibiotic in another drug class. Here are some common doctor-recommended alternatives based on your health issue: