Urinary tract infections
Bactrim DS is FDA-approved to treat UTIs caused by Escherichia coli, Klebsiella species, Enterobacter species, Morganella morganii, Proteus mirabilis, and Proteus vulgaris bacteria.
Otitis media
Bactrim DS is FDA-approved to treat otitis media in pediatric patients caused by Streptococcus pneumoniae or Haemophilus influenzae bacteria.
Chronic bronchitis
Bactrim DS is FDA-approved to treat chronic bronchitis caused by Streptococcus pneumoniae or Haemophilus influenzae bacteria.
Shigellosis
Bactrim DS is FDA-approved to treat gastroenteritis caused by Shigella flexneri or Shigella sonnei bacteria.
Pneumocystis jiroveci pneumonia
Bactrim DS is FDA-approved to treat Pneumocystis jiroveci pneumonia. It can also function as prophylaxis against P. jiroveci pneumonia in immunosuppressed patients with a high risk of developing P. jiroveci pneumonia.
Traveler's diarrhea
While not the first line option, Bactrim DS is FDA-approved to treat traveler's diarrhea caused by enterotoxigenic E. coli bacterial infections.