Stendra (avanafil) prescription available online

If you are suffering from erectile dysfunction, Stendra (avanafil) can help. Get a new prescription or refill of Stendra from a board-certified doctor online.*

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Relief for ED symptoms

Available as a oral table

Take control of your sexual health

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Stendra (avanafil)

Stendra belongs to a drug class known as phosphodiesterase 5 (PDE5) inhibitors, which relax muscles in the walls of blood vessels and increases blood flow to the penis.

Stendra is used to treat erectile dysfunction (ED). Stendra is available only by prescription.

Stendra may be prescribed as an oral tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Stendra,it is important to take it as directed by your healthcare provider, which is usually 15 minutes before sexual activity.

Stendra uses

There is one FDA-approved use for Stendra, but it may also be used off-label to treat other conditions. Your online healthcare provider may prescribe it for the following reason. It’s also possible that your doctor may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Erectile dysfunction

    Stendra is FDA-approved to treat male sexual function problems, such as erectile dysfunction (ED). It works by increasing blood flow to the penis, which can help men get and keep an erection. Stendra does not protect against sexually transmitted diseases or infections.

Stendra side effects

  • The side effects associated with taking Stendra are typically mild. Some of Stendra side effects are associated with low blood pressure. Common side effects of Stendra may include:

    • Headache

    • Flushing (warmth, redness, or tingly feeling)

    • Cold symptoms, such as stuffy nose or sore throat

    Other side effects, which are less common but might be more severe, could include:

    • Sudden vision loss

    • Shortness of breath

    • Lightheadedness, or feeling like you're going to pass out

    You should call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. The use of Stendra in children under age 18 is not recommended.

How to take Stendra

Your pharmacist will provide you with instructions on how to take your Stendra prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Stendra can come in different doses, so be sure to follow the specific instructions on your prescription. Stendra is typically taken only when needed, about 15 to 30 minutes before sexual activity, at a dose of either 50, 100 or 200 mg. You can take Stendra with or without food. 

Stendra can help you achieve an erection when sexual stimulation occurs. However, an erection will not happen just by taking avanafil.

What to avoid while taking Stendra

Stendra has many drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as other drugs. 

Possible drug interactions with Stendra include:

  • Other ED medications, such as Viagra (sildenafil) and Cialis (tadalafil)

  • Certain antibiotic and antifungal medicines

  • Medications used to treat high blood pressure or prostate disorder

  • Hepatitis C medication

  • HIV/AIDs medication

Drinking alcohol while taking avanafil can cause low blood pressure, which can lead to dizziness, lightheadedness, and other adverse effects. Avoid using Stendra with recreational drugs called "poppers."

Avoid taking avanafil more than once in a 24 hour period. Call your doctor for medical advice if you experience a painful or prolonged erection.

Medication alternatives to Stendra

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other PDE5 inhibitors or an ED medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Stendra prescription FAQs

  • How much does Stendra cost?

    Depending on your pharmacy, Stendra costs around $2,067 for thirty 50 mg oral tablets without insurance, but insurance may help cover a portion of the cost. Also, generic brands, such as avanafil, may offer a more affordable alternative. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Stendra prescription?

    Stendra (avanafil) is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take Stendra?

    To make sure Stendra is safe for you, tell your doctor if you have:

    • Heart disease, heart failure, or pulmonary arterial hypertension

    • Angina (chest pain)

    • History of heart attack or stroke

    • Severe high blood pressure

    • Low blood pressure

    • Hearing or vision problems

    • Liver or kidney disease

    • Bleeding disorders, such as sickle cell anemia

    • Stomach ulcer

    • Allergic reaction

  • How long does it take for Stendra to kick in?

    Stendra starts working within 15 minutes of your dose. It's best to take Stendra 15–30 minutes before sexual activity.

  • How many Stendra can you take in a day?

    The typical dose for Stendra ranges from 50 mg to 200 mg taken as needed to be used no more than once daily. Do not take Stendra more than once in 24 hours at any dose without your doctor's approval. 

  • Can you overdose on Stendra?

    Yes, it's possible to overdose on Stendra. Overdose symptoms may include severe low blood pressure (hypotension), difficulty breathing, sudden vision changes, and fainting.

  • Does Stendra work as well as Viagra?

    Studies suggest that Stendra is comparable in efficacy to Viagra, as well as other PDE5 inhibitors.

  • What happens if I miss a dose of Stendra?

    Since Stendra is taken as needed, you're unlikely to miss a dose.

  • What happens if I take too much Stendra?

    If you've taken too much Stendra, seek emergency medical attention or contact your local poison control center.

3 simple steps to request your Stendra prescription today 

Step 1

Book a Stendra prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Stendra prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Stendra prescription.

We can send prescriptions to any local pharmacy.

Stendra prescription pricing details

How pricing works

To get a new or refill on your Stendra prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.