Nesina (alogliptin) prescription available online 

If you are suffering from type 2 diabetes, Nesina (alogliptin) can help. Get a new prescription or refill of Nesina from a board-certified doctor online.*

Book an appointment

Manage type 2 diabetes effectively

Control your blood sugar levels

Request Nesina in as little as 15 minutes, with or without insurance*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Nesina (alogliptin)

Nesinais considered a dipeptidyl peptidase-4 (DPP-4) inhibitor, which functions by inhibiting DPP-4, which increases levels of active incretins, which in turn stimulates insulin release. This results in a decrease in fasting and post-meal blood glucose levels. Nesina is taken in correlation to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Nesina is available only by prescription. It is available in a generic formulation under the name, alogliptin, as well as under different brand names, including Vipidia Kazano, Vipidomet (with metformin) Oseni, and Incresync (with pioglitazone)

Nesina may be prescribed as tablets. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed. Nesina comes in the following dosage forms:

  • 6.25 mg tablet

  • 12.5 mg tablet

  • 25 mg tablet

If you are prescribed Nesina, be sure to complete the full course of the dipeptidyl peptidase-4 (DPP-4) inhibitor unless your doctor specifically tells you to stop.

If you don’t complete your prescription, the dipeptidyl peptidase-4 (DPP-4) inhibitor may not fully treat your type 2 diabetes. 

Nesina uses

There are many FDA-approved uses for Nesina, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your health care provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Type 2 diabetes

    Nesina can help you live a healthier lifestyle by slowing the progression of type 2 diabetes and controlling your blood sugar levels. Blood sugar control helps prevent kidney problems, nerve problems, and sexual function. Proper control of your diabetes can also lower your risk of heart attack or stroke.

Nesina side effects

  • The side effects associated with taking Nesina are typically moderate. Nesina has some common side effects. They may include:

    • Joint pain

    • Headache

    • Cold symptoms, such as stuffy or runny nose and sore throat

    Other side effects, which are less common but might be more severe, could include:

    • Severe stomach pain that may move to your back

    • Vomiting

    • Unusual tiredness

    • Severe joint pain

    • Pain in the upper stomach

    • Dark urine

    • Jaundice

    • Fever

    • Severe skin reactions

    • Severe allergic reactions, including swelling of the eyes, face, lips, tongue, or throat

    • Swelling of the feet, ankles, or legs

    • Difficulty breathing or swallowing

    • Shortness of breath

    You should call your doctor if you notice any of these adverse effects, or if you develop any other new or concerning symptoms.

How to take Nesina

Your pharmacist will provide you with instructions on how to take your Nesina prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Nesina can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed once daily.

Nesina comes in the following dosage forms:

  • 6.25 mg tablet

  • 12.5 mg tablet

  • 25 mg tablet

According to the FDA:

  • Nesina can be taken with or without food.

  • The recommended dose in patients kidney function is 25 mg once daily.

  • Dosage has to be adjusted by the doctor or pharmacist if patient has moderate or severe renal impairment or end-stage renal disease (ESRD).

It is important to take Nesina exactly as prescribed by your doctor, as skipping doses or changing the schedule can increase the risk of developing low blood sugar levels. Nesina should be taken at the same time each day to maintain an even level in the blood.

What to avoid while taking Nesina

Nesina has 255 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Drug interactions may change the way Nesina works and could possibly jeopardize your health. Nesina may interact with other drugs such as:

  • Aspirin

  • B-12

  • Captopril

  • Chlorpropamide

  • Dulaglutide

  • Folic acid

  • Glimepiride

  • Repaglinide

  • Tolazamide

  • Tolbutamide

This is not a complete list of drug interactions. Nesina can also interact with many forms of insulin.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Nesina. Moderate alcohol consumption generally does not cause blood glucose level to fluctuate if your diabetes is under control. However, alcohol consumption while taking this medication increases the risk for a severe low blood sugar (hypoglycemia).

Nesina is not expected to be harmful to an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant during treatment. Tell your doctor immediately if you are breast-feeding a baby before taking this medicine.

Medication alternatives to Nesina

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another DPP-4 inhibitor, or diabetes medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Nesina FAQs

  • How much does Nesina cost?

    The cost for 30 Nesina 25 mg oral tablets is around $420 depending on the pharmacy you visit. Price varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Nesina prescription?

    Our doctors can refill your prescription online if you qualify. Nesina is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Does Nesina cause weight gain?

    No. Nesina does not cause weight gain.

  • Who should not take Nesina?

    You should not use Nesina if you are have the following conditions:

    • Allergic to alogliptin or metformin,

    • Severe kidney disease

    • Liver disease, pancreatitis

    • Type 1 diabetes mellitus

    Tell your doctor immediately if you have any one of these medical conditions.

  • Can Nesina be crushed?

    No, Nesina is to be taken once daily with or without food, and swallow whole.

  • What happens if I miss a dose of Nesina?

    If you miss a dose of Nesina, skip the missed dose and go back to your regular dosing schedule. Avoid double doses.

  • What happens if I take too much Nesina?

     Taking too much Nesina can lead to some serious side effects such as low blood sugar levels (hypoglycemia). If you experience these side effects, it is important to seek immediate medical attention.

3 simple steps to request your Nesina prescription today 

Step 1: Book an appointment

Step 1

Book a Nesina prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Nesina prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Nesina prescription.

We can send prescriptions to any local pharmacy.

Nesina prescription pricing details

How pricing works

To get a new or refill on your Nesina prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.