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Can You Get a Sertraline Prescription Online?

Blog Antidepressants

Can You Get a Sertraline Prescription Online?

August 6, 2020 Read Time - 5 minutes

About Author

Christina has been a writer since 2010 and has an M.F.A. from The New School for Social Research. Christina specializes in writing about health issues and education.

Warning: The use of certain antidepressants to treat major depressive disorder (MDD) in adolescents may increase the risk of suicidal ideations and behaviors. While taking antidepressants mental health can change in unexpected ways. You should call a doctor right away if you experience any suicidal thoughts. Always talk to a doctor about the risks and benefits of taking antidepressant medication before beginning treatment.

Can You Get a Sertraline Prescription Online?

Yes, you can get a Sertraline prescription online by booking an appointment with a top online doctor here at PlushCare.

If you are suffering from symptoms of anxiety or depression, you might have heard about sertraline as a beneficial treatment for major depressive disorder and other mood disorders.

You may have questions about the benefits and side effects of taking sertraline. Here is a rundown of helpful facts that you can use to make a decision about whether sertraline is right for you.

  • Book on our free mobile app or website.

    Our doctors operate in all 50 states and same day appointments are available every 15 minutes.

  • See a doctor, get treatment and a prescription at your local pharmacy.

  • Use your health insurance just like you normally would to see your doctor.

Book an appointment PlushCare-App-Steps

What is Sertraline?

Sertraline belongs to a class of drugs that are known as selective serotonin reuptake inhibitors (SSRIs). Other types of SSRIs include Luvox CR (fluvoxamine), Paxil (paroxetine), Celexa (citalopram), and Prozac (fluoxetine).

In 1991, the FDA approved sertraline for use in the United States and it is used to treat conditions such as major depressive disorder, post-traumatic stress disorder, panic disorder, premenstrual dysphoric disorder, social anxiety disorder, and obsessive-compulsive disorder.

How Does Sertraline Work?

Mood disorders are caused by an imbalance between serotonin and other neurotransmitters in your brain. Medications such as sertraline work by restoring your chemical balance of neurotransmitters.

When serotonin is taken up by the nerves and then released, this process is known as a re-uptake. SSRIs like sertraline block the reuptake of serotonin. This helps maintain the balance of neurotransmitters in your brain.

Sertraline Dosage and Treatment

Sertraline is usually taken by mouth once a day as directed by your doctor. It comes in tablet or liquid form and can be taken either with or without food. Do not chew these tablets or crush these tablets.

If taken in liquid form, sertraline should be mixed with another liquid such as water, lemonade, ginger ale, orange juice, or lemon-lime soda. It is normal for the mixture to look cloudy and you should drink it right away.

Do not mix with any other liquids than the ones mentioned, do not mix in advance and take immediately after mixing.

To reduce the risk of side effects, your doctor may start you off on a low dose of sertraline and incrementally increase the dosage based on your response to the treatment. This will help reduce the risk of side effects. You should take this medication regularly at the same time each day.

Your doctor may prescribe this medication for premenstrual problems. The dosage is commonly taken every day or just for the two weeks before the start of your period.

Even if you feel better, don’t stop taking sertraline. You should consult with your doctor before discontinuing use as it could cause unwanted side effects such as mood swings, sleep changes, headache, and fatigue.

To prevent side effects, your doctor will taper off your dosage of sertraline gradually. Other side effects when stopping sertraline may include:

  • Flu-like symptoms
  • Nausea
  • Abdominal cramps
  • Memory impairment
  • Lightheadedness
  • Dizziness
  • Lack of appetite
  • Diarrhea
  • Vomiting
  • Sweating
  • Chills

Benefits of Sertraline

Sertraline and other SSRIs benefit you by restoring the balance of serotonin in your brain. These medications can increase your level of energy, help to improve your sleeping patterns, and bring back your interest in daily tasks.

They may also help improve your mood and decrease your anxiety and the nagging, unwanted thoughts that lead to a panic attack. Sertraline also reduces the urge to engage in repetitive tasks such as counting and hand-washing that can interfere with daily living.

Side Effects of Sertraline

Generally, the side effects of sertraline are minimal. Some common side effects include:

  • Sleepiness
  • Insomnia
  • Dry mouth
  • Weight loss
  • Sweating
  • Headache
  • Dizziness
  • Nausea
  • Upset stomach
  • Loss of appetite
  • Diarrhea
  • Constipation
  • Nervousness
  • Lack of interest in sex
  • Abnormal ejaculation
  • Skin rash

More serious side effects can occur but are uncommon. Seek medical assistance if you experience any of the following symptoms:

  • Irregular heartbeats
  • Prolonged erection
  • Abnormal bleeding
  • Suicidal thoughts
  • Allergic reaction
  • Worsening of depression
  • Mania (rare)
  • Hyponatremia
  • Decreased liver function
  • Serotonin syndrome

Considerations and Precautions of Sertraline

Drug Interactions

Sertraline should not be taken with monoamine oxidase inhibitor (MAOI) antidepressants. Some examples include:

  • Nardil (phenelzine)
  • Marplan (isocarboxazid)
  • Eldepryl (selegiline)
  • Parnate (tranylcypromine)

Taking a combination of SSRIs and MAOIs can lead to symptoms such as confusion, tremors, high blood pressure, hyperactivity, or coma.

If you are switching between sertraline and an MAOI, your doctor may recommend that you wait a period of 14 days before starting a new medication.

Other drugs that may cause adverse reactions in combination with sertraline include:

  • Coumadin
  • Demerol
  • Tramadol
  • St. John’s Wort
  • Tryptophan
  • Pimozide
  • Jantoven
  • Zyvox 
  • Book on our free mobile app or website.

    Our doctors operate in all 50 states and same day appointments are available every 15 minutes.

  • See a doctor, get treatment and a prescription at your local pharmacy.

  • Use your health insurance just like you normally would to see your doctor.

Book an appointment PlushCare-App-Steps

Can You Buy Sertraline Online?

Some websites may claim that you can buy sertraline online without a prescription for a very low cost. These kinds of deals are usually “too good to be true” and you may be taking a risk of getting a subpar medication.

Luckily, there are legitimate healthcare websites like PlushCare that offer consultation with a certified and trusted online doctor who can provide a prescription for medications such as sertraline. You can make a convenient appointment to consult with a qualified doctor via telephone or video chat to discuss your current medications and medical history to see if sertraline is the right medication for you.

The first step is to make an appointment with a PlushCare medical professional. Click here or call (888) 660-5348 to schedule an appointment to discuss how you might benefit from taking sertraline.

Read more of our antidepressant series:

Article Sources

National Institute of Mental Health. Depression. Accessed September 29, 2019 at

Mayo Clinic. Selective serotonin reuptake inhibitors (SSRIs). Accessed September 29, 2019 at

Medline Plus. Sertraline. Accessed September 29, 2019 at

Reviewed By


Dr. Maria Glukhovsky

Dr. Maria Glukhovsky, Pharm.D. has been a pharmacist for the past 12 years, clinical educator across many disease states and a clinical instructor at Jefferson School of Pharmacy. She loves to educate her patients and everyone around her on the proper use of medications and top disease management techniques to improve health and wellbeing.

Most PlushCare articles are reviewed by M.D.s, Ph.Ds, N.P.s, nutritionists and other healthcare professionals. Click here to learn more and meet some of the professionals behind our blog. The PlushCare blog, or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment. For more information click here.

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