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Desogen Birth Control Review

writtenByWritten by: Jennifer Nelson
Jennifer Nelson

Jennifer Nelson

Jennifer is a contributing health writer who has been researching and writing health content with PlushCare for 3 years. She is passionate about bringing accessible healthcare and mental health services to people everywhere.

Read more posts by this author.

November 24, 2020 Read Time - 5 minutes

Is Desogen Right For Me

When deciding which birth control to use, it can be helpful to read reviews from others who have tried it. That’s why we’ve put together this information about Desogen and its potential side effects with real user reviews. Hopefully, it can guide your decision on whether to try Desogen birth control.

Only a doctor can decide if Desogen is appropriate for you. This information is not intended to be a replacement for a discussion with a trusted doctor.

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Oral contraceptives like Desogen do not protect against HIV, gonorrhea, chlamydia, or other sexually transmitted diseases (STDs). Some STDs have no symptoms, and many are becoming more common.

Read: How to Get Tested for Herpes and Why It Matters

What Kind of Birth Control Is Desogen?

Desogen is a combination birth control pill that contains the hormones Ethinyl estradiol and Desogestrel. These hormones help prevent ovulation, make it harder for sperm to reach the uterus, and make it more difficult for fertilized eggs to implant themselves in the uterus.

Desogen Side Effects

Like any medication, Desogen may cause side effects, some of which may be severe. Potential side effects of Desogen include:

  • Vomiting
  • Nausea
  • Headache
  • Swelling of the feet or ankles
  • Breast tenderness
  • Acne
  • Irregular periods
  • Weight change
  • Increased blood pressure
  • Severe abdominal pain
  • Depression
  • Blood clots
  • Stroke
  • Heart attack
  • Liver problems

Who Should NOT Take Desogen?

Desogen is generally considered safe. However, it isn’t appropriate for everybody. Always tell your doctor about your medical history and any medications you take. Definitely mention if you smoke, are overweight, are over 35, or have had any of the following:

  • High blood pressure
  • Blood clots
  • Cancer
  • Migraines
  • Heart problems
  • Liver disease
  • Diabetes
  • Abnormal breast exam
  • High cholesterol
  • Depression
  • Gallbladder problems
  • Stroke
  • Thyroid problems
  • Unusual vaginal bleeding

Read: How Long Does it Take for Birth Control to Work?

To prevent potentially serious interactions, make sure you tell your doctor if you take any of the following medications:

  • Ospemifene
  • Tizanidine
  • Tamoxifen
  • Tranexamic acid
  • Aromatase inhibitors (like anastrozole, exemestane)
  • Certain combination products used to treat chronic hepatitis C (ombitasvir/paritaprevir/ritonavir with or without dasabuvir)
  • Rifamycins (like rifampin, rifabutin)
  • St John’s wort
  • Modafinil
  • Griseofulvin
  • HIV drugs
  • Drugs used to treat seizures

Frequently Asked Questions

Does Desogen cause weight gain?

Desogen does have the potential to cause weight gain. Talk to your doctor if you’re concerned about this potential side effect.

Are Desogen and Apri the same?

Yes and no. Desogen and Apri are different brand names of desogestrel and ethinyl estradiol tablets, so they have the same main ingredients. However, the inactive ingredients in each may cause different side effects.

Do you get periods on Desogen?

Generally, you will take the “active” pills of Desogen for three weeks, followed by one week of placebo or lower-dose pills, when you will have your period. Talk to your doctor about which birth control might be best if you want to skip your periods.

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Get Desogen Online

PlushCare makes it simple and affordable to get Desogen online.

Jusy book a phone or video appointment with one of the trusted doctors at PlushCare. You’ll tell them about your health history and any medications you take, and they’ll ask you some other questions to make sure Desogen is right for you. If they think it is, they’ll send an electronic prescription to your pharmacy, where you can pick it up in as little as a few hours.

If our doctors determine Desogen is not right for you, they may recommend a different birth control medication or method.

Making an appointment with PlushCare to get Desogen online is simple. You can make an appointment any time by clicking here, or downloading the PlushCare App from either Google Play or The App Store.

Desogen Reviews

3/1/2020 – “This is absolute rubbish. I been recently changed from microgynon to this desorex just because I am almost 35 and smoking. On this new one I have headaches daily, muscle pains, apparently I am so moody, and I have blood coming nonstop…. What is the point of taking these pills if I can’t have sex anyway?”

3/21/2018 – “I was on this pill for about a year because I didn’t know any better. I had a steady period for the first three months, straight through. I also lactated during that time. Once those symptoms went away, my mood became terrible and remained so for the next 9 months (I’m normally very happy and easy going). The following year, I got a new doctor and switched to OrthoCyclen. Been great ever since. That year was a nightmare.”

10/23/2014 – “This was the first birth control pill I went on, and I wish I never stopped. I’ve been on like 4-5 other types but this one has been the best so far from my experience. The only downside was gaining 5 pounds, but it wasn’t noticeable at all. If my current pill doesn’t work out, I will be requested a prescription for Desogen again.”

4/4/2014 – “I was on Desogen for 7 years and never got pregnant, had shorter, lighter periods. All medicines have side effects that being said; the downside was slight increase of my blood pressure & slight weight gain. When I was ready to start my family it only took me 2 months to get pregnant. Now I have to be on a different pill because I’ve had my baby & our hormones change but haven’t found a pill that works as well as Desogen did.”

8/21/2013 – “I’ve been taking Desogen for a year now after not being happy with Lutera. As birth control it works good (i.e. not pregnant). I don’t have any breast tenderness like I used to and I have gone up a cup size. I had mild to moderate acne before taking the pill and it has helped it clear up a lot! I only break out right before a period. And my periods are very predictable and only last 3 days (versus the usual 7 I had experienced before). However, when I first started taking it I noticed a prolonged time of spotting but it did eventually go away and I am pleased overall with this pill!”

Read More


FDA. Desogen Tablets. Accessed on November 24, 2020 at

RxList. Desogen. Accessed on November 24, 2020 at User Reviews for Desogen. Accessed on November 24, 2020 at

Most PlushCare articles are reviewed by M.D.s, Ph.Ds, N.P.s, nutritionists and other healthcare professionals. Click here to learn more and meet some of the professionals behind our blog. The PlushCare blog, or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment. For more information click here.

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