Zyloprim (allopurinol) prescriptions available online

About Zyloprim (allopurinol)

Zyloprim is a type of medication called a xanthine oxidase inhibitor, which functions by blocking the enzyme responsible for the metabolism of xanthine to the production of uric acid. The prevention of this reaction prevents the buildup of uric acid levels that causes gout. 

Like any xanthine oxidase inhibitor, this medication is only meant to be used for a limited period of time, and the patient must be re-evaluated before discontinuing the drug.

Zyloprim is primarily used to treat and prevent gout, but may also be used to reduce the chance of developing kidney stones caused by uric acid and calcium oxalate. It is also used to prevent what is known as tumor lysis syndrome, which can occur in patients receiving certain cytotoxic therapies as part of their cancer treatments.

Zyloprim is available only by prescription. It is available in a generic formulation as allopurinol, as well as under different brand names, including Altacoron, Xyloprim, Neuroplat, and Radodyl, among others.

Zyloprim may be prescribed as a once-daily tablet. Zyloprim should not be taken with other medications that interfere with the absorption of uric acid, such as methotrexate or sulfasalazine, because it may lead to low uric acid levels. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed.

If you are prescribed Zyloprim, be sure to continue the course of the xanthine oxidase inhibitor unless your doctor specifically tells you to stop. If you don’t complete your prescription, the xanthine oxidase inhibitor may not adequately manage your condition.

What to avoid while taking Zyloprim

Zyloprim has 59 possible drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

It is important to avoid alcohol, tea, coffee, and other hot beverages while taking Zyloprim.

Before taking Zyloprim (allopurinol), it is important to tell your doctor if you have ever had a severe reaction to it in the past, or have any other allergies. This product may contain certain inactive ingredients that can cause allergic reactions or other problems. Talk to your doctor for more details.

Your doctor should be informed about your medical history before prescribing this medication. This is especially true if you have had any of the following:

• Kidney or liver disease

• Diabetes

• High blood pressure (hypertension)

• Unusual diets (e.g., fasting)

• Family or personal history of HLA-B*5801-positive immune system 

Zyloprim (allopurinol) may make you drowsy. The use of alcohol or marijuana can worsen the condition. When taking Zyloprim (allopurinol), avoid operating any machinery, driving, or performing any task that requires alertness. The use of alcohol may also decrease the potential effectiveness of this drug; therefore, please limit alcohol consumption when taking this medication. Some research shows that regular alcohol consumption may increase the risk of kidney failure in people who have congestive heart failure. Regular alcohol consumption also negatively affects liver function.

Older adults may be at increased risk of side effects when using this drug. This is because as kidney function declines with age, it may be less effective at removing Zyloprim from the system.

Pregnant patients should discuss the risk and benefits of taking Zyloprim with your doctor. Zyloprim has the ability to pass into breast milk; nursing patients should consult their doctor before breastfeeding.