Zyloprim (allopurinol) prescriptions available online

If you are suffering from joint pain or swelling, our doctors are here to help. If you are experiencing gout, Zyloprim (allopurinol) can help. Get a new prescription or refill of Zyloprim from a board-certified doctor online.*

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*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Zyloprim (allopurinol)

Zyloprim is considered a xanthine oxidase inhibitor, which functions by blocking the enzyme responsible for the metabolism of xanthine to the production of uric acid. The prevention of this reaction prevents the buildup of uric acid levels that causes gout. 

Like any xanthine oxidase inhibitor, this medication is only meant to be used for a limited period of time, and the patient must be re-evaluated before discontinuing the drug.

Some conditions that Zyloprim is known to treat include gout,elevated levels of uric acid in the body (usually caused by certain cancers and cancer treatments), and kidney stones. Other conditions include:

  • Vitamin B12 deficiency

  • Rheumatoid arthritis

  • Gout-related bone disorders

Zyloprim is available only by prescription. It is available in a generic formulation as allopurinol, as well as under different brand names, including Altacoron, Xyloprim, Neuroplat, and Radodyl, among others.

Zyloprim may be prescribed as a once-daily tablet. Zyloprim should not be taken with other medications that interfere with the absorption of uric acid, such as methotrexate or sulfasalazine, because it may lead to low uric acid levels. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed.

If you are prescribed Zyloprim, be sure to complete the full course of the xanthine oxidase inhibitor unless your doctor specifically tells you to stop. If you don’t complete your prescription, the xanthine oxidase inhibitor may not fully treat your condition.

Zyloprim uses

There are many FDA-approved uses for Zyloprim, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your doctor may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Gout

    A common FDA-approved use for Zyloprim is to treat gout.

    Gout is a form of inflammatory arthritis. Gout attacks are known to be one of the most painful forms of arthritis, characterized by excruciating attacks that occur suddenly in a single joint – frequently in the middle of the night. The most commonly affected joint is the big toe, but gout is also seen in the ankles, knees, wrists, and hands.

    Zyloprim functions by blocking the enzyme responsible for the metabolism of xanthine to the production of uric acid. This prevents the buildup of uric acid levels in people with increased uric acid levels, often caused by certain cancers and cancer treatments, as well as other drugs.

Zyloprim side effects

  • Most side effects associated with taking Zyloprimare typically mild. They may include:

    • Upset stomach

    • Nausea

    • Diarrhea

    • Drowsiness


    In the event that these symptoms persist or worsen, please consult your doctor or pharmacist.

    It should be understood that the prescription of this medicine is based on a benefit/risk assessment made by your doctor. The possibility of mild side effects should not be the reason to discontinue the use of this medication. Most people who use this medication do not experience serious side effects. Inform your doctor right away if you experience any serious side effects.

    This medication also has the potential to cause a non-serious rash. It is possible that you will not be able to tell the difference between a non-serious rash and a serious allergic reaction. Please tell your doctor and seek help right away if any allergic reaction develops.

    There is also a chance of serious allergic reaction (possibly fatal) to this drug; although this is rare. Please seek immediate medical attention if you notice any of the following symptoms of an allergic reaction:

    • Rash

    • Itching/swelling (especially of the face/tongue/throat)

    • Severe dizziness

    • Trouble breathing


    You should also call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. They may include:

    • Fever

    • Headache

    • Muscle aches and weakness

    • Insomnia

    • Muscle cramps

    • Dehydration

    • Hair loss

    • Irregular heartbeat

How to take Zyloprim

Your pharmacist will provide you with instructions on how to take your Zyloprim prescription for your allopurinol treatment.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Zyloprim is administered in oral form. It is usually taken at least once daily at the same time every day, or based on the medical guidelines provided by your doctor. In order to reduce the incidence of upset stomach, Zyloprim should be taken after a meal. If your dose happens to be more than 300 milligrams a day, you will have to take several smaller doses during the day.

The typical dose is 100 to 200 milligrams a day. It is important to drink water when using this medication. Each dose should be taken with a full glass of water in addition to at least 8 more glasses a day. If there is a medical reason for you to drink less water, please consult your doctor for more instructions. There are also other preventive measures that you may be instructed to do in order to decrease uric acid levels in your urine.

Some specific instructions may include:

  1. Do not exceed the recommended dose. Do not take more than specified amount or Zyloprim will lose its effectiveness and may cause side effects.

  2. If you take Zyloprim with food, especially cold foods, drink a small amount of water 30 minutes before taking Zyloprim.

The dosage prescribed to you will be based on your particular medical condition and response to treatment. It is crucial that you use the medication according to your doctor's prescription guidelines.

If you are taking the medication for gout, it may take up to several weeks before this medicine has an effect. While the body seeks to remove excess uric acid, it is not uncommon for you to experience more gout attacks for several months while on this medication.

Dosages might be adjusted for certain patients. Always follow the directions given by your doctor and the instructions on the prescription label.

What to avoid while taking Zyloprim

Zyloprim has 59 possible drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

It is important to avoid alcohol, tea, coffee, and other hot beverages while taking Zyloprim. Do not take Zyloprim with other drugs, including certain antibiotics, blood thinners, or diabetes medicines. If you are taking certain medicines, it may be unsafe to take Zyloprim.

Before taking Zyloprim (allopurinol), it is important to tell your doctor or pharmacist if you have ever had a severe reaction to it in the past, or have any other allergies. This product may contain certain inactive ingredients that can cause allergic reactions or other problems. Talk to your doctor or pharmacist for more details.

Your doctor should be informed about your medical history before prescribing this medication. This is especially true if you have suffered any of the following:

  • Kidney or liver disease

  • Diabetes

  • High blood pressure (hypertension)

  • Unusual diets (e.g., fasting)

Zyloprim (allopurinol) may make you drowsy. The use of alcohol or marijuana can worsen the condition. When taking Zyloprim (allopurinol), avoid operating any machinery, driving, or performing any task that requires alertness. The use of alcohol may also decrease the potential effectiveness of this drug; therefore, please limit alcohol consumption when taking this medication. Some research shows that regular alcohol consumption may increase the risk of kidney failure in people who have congestive heart failure. Regular alcohol consumption also negatively affects liver function.

Older adults may be at increased risk of side effects when using this drug. This is because as kidney function declines with age, it may be less effective at removing Zyloprim from the system.

Pregnant patients should discuss the risk and benefits of taking Zyloprim with your doctor. Zyloprim has the ability to pass into breast milk; nursing patients should consult their doctor before breastfeeding.

Medication alternatives to Zyloprim

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another xanthine oxidase inhibitor or a gout medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Zyloprim prescriptions FAQs

  • How much does Zyloprim cost?

    Zyloprim costs $1,155 for 100 tablets (i.e., 200 mg). Some insurance programs may cover up to 200 mg. Some prescriptions and plans require you to see a doctor to pick up a prescription each month, which can be done online by booking an appointment with one of our trusted doctors. Price varies with insurance coverage. Our prescription discount card helps members save up to 80% on prescriptions.

  • How can I refill my Zyloprim prescription?

    Zyloprim is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.

  • Who should not take Zyloprim?

    Zyloprim should not be taken by anyone with a history of kidney problems, heart conditions, uncontrolled high blood pressure, liver problems.

  • What happens if I miss a dose of Zyloprim?

    If you miss a dose of Zyloprim, skip the missed dose and go back to your regular dosing schedule. Avoid double doses.

  • What happens if I take too much Zyloprim?

    If you take more Zyloprim than the recommended dose, it affect your liver function. With high levels of Zyloprim in your body you may experience the following symptoms:

    • Nausea

    • Skin rash

    • Diarrhea

  • Is Zyloprim the same as allopurinol?

    Zyloprim is the same as allupurinol. Allopurinol is the generic name, while Zyloprim is the brand name.

  • When should Zyloprim be given?

    Zyloprim is administered in oral form. It is usually taken at least once daily at the same time every day, or based on the medical guidelines provided by your doctor. In order to reduce the incidence of upset stomach, Zyloprim should be taken after a meal. If your dose happens to be more than 300 milligrams a day, you will have to take several smaller doses during the day.

3 simple steps to request your Zyloprim prescription today 

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Step 1

Book a Zyloprim prescription request appointment.

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Step 2

Talk to your medical provider regarding your Zyloprim prescription.

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Step 3: pick up at local pharmacy

Step 3

Pick up your Zyloprim prescription.

We can send prescriptions to any local pharmacy.

Zyloprim prescription pricing details

How pricing works

To get a new or refill on your Zyloprim prescription, join our monthly membership and get discounted visits.

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Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

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Paying without insurance

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First month free

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30 days of free membership

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  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

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Zyloprim prescription resources

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