Zyloprim has 59 possible drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.
It is important to avoid alcohol, tea, coffee, and other hot beverages while taking Zyloprim.
Before taking Zyloprim (allopurinol), it is important to tell your doctor if you have ever had a severe reaction to it in the past, or have any other allergies. This product may contain certain inactive ingredients that can cause allergic reactions or other problems. Talk to your doctor for more details.
Your doctor should be informed about your medical history before prescribing this medication. This is especially true if you have had any of the following:
-
Kidney or liver disease
-
Diabetes
-
High blood pressure (hypertension)
-
Unusual diets (e.g., fasting)
-
Family or personal history of HLA-B*5801-positive immune system
Zyloprim (allopurinol) may make you drowsy. The use of alcohol or marijuana can worsen the condition. When taking Zyloprim (allopurinol), avoid operating any machinery, driving, or performing any task that requires alertness. The use of alcohol may also decrease the potential effectiveness of this drug; therefore, please limit alcohol consumption when taking this medication. Some research shows that regular alcohol consumption may increase the risk of kidney failure in people who have congestive heart failure. Regular alcohol consumption also negatively affects liver function.
Older adults may be at increased risk of side effects when using this drug. This is because as kidney function declines with age, it may be less effective at removing Zyloprim from the system.
Pregnant patients should discuss the risk and benefits of taking Zyloprim with your doctor. Zyloprim has the ability to pass into breast milk; nursing patients should consult their doctor before breastfeeding.