Remeron (mirtazapine) prescription available online

If you live with mental health disorders like depression, Remeron (mirtazapine) can help. Get a same-day prescription or refill of Remeron today from a caring, board-certified primary care doctor online.*

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FDA-approved for depression

May ease depressive symptoms over time

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*Prescriptions are provided at the doctor’s discretion. Plushcare doctors are primary care physicians, not psychiatrists. Some patients may be best managed in-person or under the care of a psychiatrist. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Remeron (mirtazapine)

Remeron is considered an alpha-2 receptor antagonist, which helps improve the balance of certain chemicals in the brain. It is also though to improve nerve cell communications within the brain.

Like any alpha-2 antagonist, this medication can only be used to treat depression. It is ineffective against acute anxiety or panic attacks because it will not relieve the symptoms in a short period of time.

Some conditions that Remeron is known to treat include depression, including major depressive disorder. Remeron is available only by prescription. It is available in a generic formulation as well as under different brand names, including mirtazapine.

Remeron may be prescribed as a capsule. In some cases, you may rather be provided with orally disintegrating tablets. An orally disintegrating tablet works similarly but dissolves on your tongue. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage that you are prescribed.

If you are prescribed Remeron, be sure to take it daily unless your doctor specifically tells you to stop.

If you stop your prescription before you're ready, your symptoms may return. If you use Remeron to treat psychiatric disorders like major depressive disorder, worsening depression may occur if you suddenly stop using the drug. Often, weaning the dose slowly is best when planning to stop any antidepressant. Talk to your doctor if you have concerns about the adverse effects that the drug may cause.

The medication is usually not advised for bipolar disorder and similar conditions, because it does not act as a mood stabilizer. 

Remeron uses

There is only one official FDA-approved use for Remeron, but it may also be used off-label to treat insomnia, if recommended by your doctor. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Depression

    Individuals with different types of depression may feel better when they take Remeron. The mirtazapine therapy that the drug uses can help to relieve such symptoms as a low mood, depressive thoughts, and other symptoms associated with depression. Similar to other drugs called antidepressants, the medication does take some time to provide an improvement to your mental illness. If needed, the doctor may combine these antidepressant drugs with other drugs over a short period of time to help with acute symptoms.

Remeron side effects

  • The side effects associated with taking Remeron are typically mild. Remeron has some common side effects. They may include:

    • Weight gain

    • Drowsiness

    • Dizziness

    • An increased appetite

    Other side effects, which are less common but might be more severe, could include:

    • White blood cell problems: In some very rare cases, medical attention is required by patients who use Remeron due to a decline in white blood cells. This can cause a sore throat, flu-like symptoms, chills, fever, coughing, and trouble breathing.

    • Serotonin Syndrome: There is a risk of serotonin syndrome among individuals who use Remeron, almost exclusively when taken alongside other drugs that incease serotonin levels. Serotonin syndrome happens when there is an excessive accumulation of serotonin in your brain. In cases of serotonin syndrome, you may experience a number of adverse effects, such as abdominal pain, facial flushing & agitation. Call 911 immediately if you feel these symptoms.

    • Low Sodium: While taking Remeron, be on the lookout for signs that your sodium levels decline. Tell your doctor if you have constant headaches and feel confused. Severe weakness, unsteadiness, and several other symptoms can develop if your sodium levels drop too low.

    You should call your doctor if you notice any of these side effects or if you develop any other new or concerning symptoms. Use of Remeron in young children under age 18 is not advised because it can cause a higher risk of serotonin syndrome, suicidal ideation, and other symptoms related to the use of the medication.

    Patients with a medical history of suicidal thoughts should mention this to their healthcare professionals. This can provide more comprehensive monitoring and support during mirtazapine therapy.

How to take Remeron

Your pharmacist will provide you with instructions on how to take your Remeron prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Remeron can come in different forms and doses, so be sure to follow the specific instructions on your prescription. It is typically prescribed only once per day. The specific instructions depending on the dosage form you use. Take a Remeron tablet with a full glass of water.

The instructions for orally disintegrating tablets are a bit different. Place the orally disintegrating tablet on your tongue and wait for it to melt. Once the orally disintegrating tablet melts, swallow several times.

What to avoid while taking Remeron

Remeron has multiple drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Some of the drug interactions to be aware of include:

  • Certain antibiotics

  • Cimetidine

  • Tramadol

  • Diazepam

  • Antifungal medications

  • Antiviral medicine

  • Migraine headache drugs

  • Seizure medications

In addition to these interactions, patients should not use other antidepressant drugs with Remeron without speaking to their doctor first. The medication may also interact with medications used to treat mood disorders, such as antipsychotics.

It is important to tell your doctor about any other drugs you use when taking Remeron. Additionally, talk to your doctor about your medical history. This can help them determine potential risks you may face when using Remeron.

Tell your doctor if you have glaucoma, low blood pressure, high cholesterol levels, or struggle with low sodium. If you experienced drug-related problems in the past with withdrawal symptoms, then mention this to the healthcare professional as well.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Remeron. Alcohol is a central nervous system depressant and may make your depression worse. In addition to worsening depression, alcohol with Remeron may also cause more severe side effects.

Medication alternatives to Remeron

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another tetracyclic antidepressant or an antidepressant in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • Depression With Anxiety

    Some patients experience both signs of generalized anxiety disorder and depression simultaneously. In these cases, doctors will likely provide prescription medicine that reduces serotonin reuptake in the brain. You can ask your doctor for medical advice about the side effects that these drugs may produce. You will likely be treated with an SSRI in these cases.

Remeron (mirtazapine) prescription FAQs

  • How much does Remeron cost?

    Prices for these tricyclic antidepressants can differ depending on the dose you need to take, as well as where you pick up the prescription. Keep in mind that there are also different dosage forms of medication to treat mental health conditions.

  • How can I refill my Remeron prescription?

    The most effective method is to keep your prescription with a specific pharmacy in the local area. This makes it easier to pick up your medicine on a monthly basis.

  • Who should not take Remeron?

    Tell your doctor if you have a personal or family history of suicidal thoughts. You should also not use the medicine of similar antidepressants that led to worsening symptoms in the past. Do not use the drug if you already use a MAO inhibitor or similar antidepressants. Apart from MAO inhibitors and other mental health drugs, note that the medication may cause interactions with certain health conditions too.

  • What can you not take with Remeron?

    Do not combine the medicine with certain drugs that are used for psychiatric disorders unless instructed by your doctor. You should also not take drugs that may also cause alterations in brain chemicals. This can cause you to develop symptoms of serotonin syndrome and similar complications.

  • How long does it take to get used to Remeron?

    Remeron is not a fast-acting drug, but rather takes a while to start working. Most people see improvements in the first eight weeks.

  • What are the serious side effects of Remeron?

    Although exceedingly rare, an allergic reaction can be fatal when a person takes this medication. You have an increased risk if you experience allergic reactions to similar types of antidepressants in the past. This can cause severe skin reactions, trouble breathing, and more.

  • How long does it take to fall asleep after taking Remeron?

    Most people find that Remeron helps to improve sleep among young adults and elderly patients. These results can usually be experienced within the first week of use.

  • What happens if I miss a dose of Remeron?

    You should be careful about a missed dose. Consider when your next dose is. If there are only a few hours left, then skip the missed dose. Talk to your doctor if you are not sure whether there is still enough time left. Do not take more than one dose to make up for a missed dose.

  • What happens if I take too much Remeron?

    A mirtazapine overdose can be fatal in some cases, and you may need to contact a local poison control center. If you take too much of the drug, then get medical attention if you experience any serious adverse effects.

3 simple steps to request your Remeron prescription today 

Step 1

Book a Remeron prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Remeron prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Remeron prescription.

We can send prescriptions to any local pharmacy.

Remeron prescription pricing details

How pricing works

To get a new or refill on your Remeron prescription, join our monthly membership and get discounted visits.

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Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

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Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.