Most major insurance plans accepted
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your Onglyza prescription today

Step 1
Book a Onglyza prescription request appointment.
Book a same day appointment from anywhere.

Step 2
Talk to your medical provider regarding your Onglyza prescription.
Visit with a doctor on your smartphone or computer.

Step 3
Pick up your Onglyza prescription.
We can send prescriptions to any local pharmacy.
Onglyza prescription pricing details
How pricing works
To get a new or refill on your Onglyza prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Onglyza prescription FAQs
How much does Onglyza cost?
Depending on your pharmacy, Onglyza costs around $505 for thirty 2.5 tablets without insurance. Fortunately, generic brands, such as saxagliptin, offer an affordable alternative.
How can I refill my Onglyza prescription?
To refill your Onglyza prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.
Who should not take Onglyza?
Avoid taking Onglyza if you have certain medical conditions, such as:
Kidney disease
Heart failure
Pancreatitis
Gallstones
Alcoholism
High triglycerides
Serious allergic reactions to insulin products
What is the best time to take Onglyza?
You can take Onglyza at any time of the day, but it's best to take Onglyza before or after a meal. Take your saxagliptin dose at the same time each day to effectively treat high blood sugar.
Can you take Onglyza and metformin together?
Yes, Onglyza and metformin can be safely taken together. Your doctor may prescribe saxagliptin and metformin to treat high blood sugar (blood glucose) levels.
Your doctor may recommend regular blood sugar testing to make sure both medications are safe for you.What happens if I miss a dose of Onglyza?
If you miss a dose of Onglyza, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose and return to your regular dosing schedule. Avoid taking two doses to make up for a missed dose.
What happens if I take too much Onglyza?
If you've taken too much Onglyza, seek emergency medical attention or contact your local poison control center. You may have signs of severe hypoglycemia (low blood sugar), such as weakness, rapid breathing, sweating, or lightheadedness.
About Onglyza (saxagliptin)
Onglyza is considered a dipeptidyl peptidase-4 (DPP-4) inhibitor, which works by increasing the amount of insulin produced by the body after meals when blood sugar is high.
Onglyza is used for glycemic control in patients with type 2 diabetes mellitus. Onglyza is available only by prescription. It is available in a generic formulation as well as under different brand names, including saxagliptin.
Onglyza may be prescribed as a tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed Onglyza, be sure to complete the full course of the diabetes medication unless your doctor specifically tells you to stop. If you don’t complete your prescription, the diabetes medication may not fully treat your type 2 diabetes mellitus.
Onglyza uses
There is one FDA-approved use for Onglyza, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons.
It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.
Type 2 diabetes mellitus
Onglyza is FDA-approved to treat type 2 diabetes mellitus in combination with diet and exercise. Onglyza is sometimes prescribed with other diabetes medications to manage high blood sugar.
Onglyza is not effective for treating type 1 diabetes or diabetic ketoacidosis.
Onglyza side effects
The side effects associated with taking Onglyza are typically mild. Most Onglyza side effects are associated with cold symptoms. Onglyza has some common side effects. They may include:
Upper respiratory tract infection symptoms, such as sore throat or stuffy nose
Painful urination
Headache
Swelling in the hands or feet
Other side effects, which are less common but might be more severe, could include:Severe joint pain
Heart problems, such as shortness of breath or unusual tiredness
Burning sensation during urination
Tell your doctor if you notice any of these side effects. Ask your doctor for medical advice if you develop any other new or concerning symptoms. The use of Onglyza in children under age 18 is not recommended.
How to take Onglyza
Your pharmacist will provide you with instructions on how to take your Onglyza prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Onglyza can come in different forms and doses, so be sure to follow the specific instructions on your prescription. For adults with type 2 diabetes, the starting saxagliptin dose typically ranges from 2.5 mg to 5 mg orally once daily, with or without food.
What to avoid while taking Onglyza
Onglyza has 377 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.
Possible drug interactions with Onglyza include:
Other oral diabetes medications, such as Ozempic (semaglutide) and Novolog (insulin aspart)
Drinking alcohol while taking Onglyza can increase the risk of high blood sugar (hyperglycemia) and low blood sugar (hypoglycemia), depending on how much you drink. Ask your doctor for medical advice about side effects before drinking alcohol.
Medication alternatives to Onglyza
If your healthcare provider prefers to put you on another treatment, they may suggest another oral diabetes medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
Type 2 diabetes mellitus