- Pediatrics
Mononucleosis
Mononucleosis (mono) treatment available online today
Request mononucleosis treatment today from our trusted, board-certified online doctors and find relief. Our licensed doctors can evaluate your symptoms and order blood tests, including a monospot test, to the lab nearest you.
Book an appointment
Medication services available for adults and kids (3+)
Top quality, board-certified doctors
Insurance accepted, but not required
*Prescriptions provided at doctor’s discretion
Most major insurance plans accepted
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request mononucleosis treatment
Step 1
Book a mononucleosis treatment appointment.
Book a same day appointment from anywhere.
Step 2
Talk to your medical provider regarding your mononucleosis symptoms.
Visit with a doctor on your smartphone or computer.
Step 3
Get tested and pick up a prescription if necessary.
We can order tests including the monospot test to the lab nearest you and send prescriptions to any local pharmacy.
Mononucleosis treatment pricing details
How pricing works
To request mononucleosis treatment and get a new or refill on a prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
- We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Mononucleosis treatment FAQs
What is the best treatment for mononucleosis?
The best treatment for infectious mononucleosis is often rest and over-the-counter medication. Because no medications can treat mono, the goal of mono treatment is to ease symptoms and treat complications.
How long is mononucleosis contagious after treatment?
After your symptoms subside, you can pass the viral infection to other people through your saliva for up to 3 months. Some studies suggest that you may still be contagious for up to 18 months.
Sometimes, the dormant virus can "wake up" and find its way into an infected person's saliva. Even though the infected person may not feel ill or show any symptoms, they can still spread the virus to other people. There's a small chance that people who have developed infectious mononucleosis in the past can pass it to others—even when they're symptom-free.
In other words, it's hard to prevent mono from spreading. Because the Epstein-Barr virus can "wake up" after being dormant, infections are common, especially among college students and young adults.How long does mono usually last?
Infectious mononucleosis typically lasts 2–4 weeks. Fortunately, these symptoms often improve with at-home treatment.
Some people experience lingering fatigue for several months after mono. During this time, be sure to protect your health by getting enough rest, drinking plenty of fluids, and avoiding strenuous activity.How long does it take to recover from mono?
Most people recover from mono within 2–4 weeks. Flu-like symptoms, such as sore throat and body aches, typically lessen within a few weeks. In rare cases, infectious mononucleosis may last for 6 months or longer, according to the Centers for Disease Control.
Fortunately, after infectious mononucleosis, your immune system develops antibodies to provide life-long immunity. In other words, you're unlikely to develop mono twice.What is the best medicine for mono?
There's no specific antibiotic or antiviral therapy to treat infectious mononucleosis, and medication for mono focuses on relieving symptoms. People react differently to different drugs, and the best medication will depend on the individual case.
If you're experiencing mono symptoms, some medications that can help relieve symptoms include:
Tylenol (acetaminophen)
Advil (ibuprofen)
Aspirin
Dexamethasone (for airway obstruction)
Learn about mononucleosis
Infectious mononucleosis, also called the "kissing disease," is a viral illness that commonly affects children, teenagers, and young adults, although it can affect people of any age. Viruses and infections, most commonly the Epstein-Barr Virus (EBV), can cause mononucleosis.
Mononucleosis (mono) is commonly spread through the saliva while kissing, but you can also get it by sharing food or drinks with someone who has mono. However, infectious mononucleosis isn't as contagious as some other infections, such as the common cold.
Mononucleosis causes
The most common cause of mono is the Epstein-Barr virus (EBV). According to Cleveland Clinic, over 90 percent of mono cases can be attributed to EBV infection.
Other viruses and infections can also cause mono. Mononucleosis symptoms may develop because of:
Adenovirus
Cytomegalovirus (CMV)
Hepatitis A, B, and C
Herpes simplex virus (HSV)
Human immunodeficiency virus (HIV)
Rubella
Toxoplasmosis
In most cases, these viruses spread through bodily fluids, especially saliva. However, they can also spread through blood and semen during sexual contact, blood transfusions, and organ transplants.
Mononucleosis symptoms
The signs and symptoms of mononucleosis will vary from person to person, and they can range from mild to severe.
Mono symptoms tend to develop gradually. Due to the virus' longer incubation period, it takes 4–6 weeks to develop mono symptoms after coming into contact with the Epstein-Barr virus.
The most common symptoms of mono include:
Extreme fatigue
Headaches, muscle aches, and body aches
Swollen lymph nodes in the neck or armpit
Swollen liver or spleen, or both
The Epstein-Barr virus can cause the body to produce an excessive number of white blood cells (lymphocytes). EBV also leads to a weakened immune system, making it harder for the body to fight infections.
How to treat mononucleosis
There's no cure for infectious mononucleosis. Antibiotics to fight bacterial infections and antiviral medications to kill other viruses do not work against infectious mononucleosis. Instead, mono treatment aims to relieve symptoms.
Depending on the severity of your symptoms, your treatment might include:
Rest: Many people with mono experience extreme fatigue. Sleep helps your body fight infection so you can feel your best.
Hydration: Be sure to drink plenty of fluids to prevent dehydration.
Pain relievers: Over-the-counter pain relievers such as non-steroidal anti-inflammatory drugs (NSAIDs), can help ease symptoms. Ibuprofen, naproxen, and acetaminophen can provide relief from headaches and body aches.
Sore throat soothers: Cough drops and saltwater gargles can help soothe a sore throat.
Avoiding sports: Strenuous activities, especially contact sports, can put pressure on an enlarged spleen, increasing the risk of rupture. Be sure to avoid contact sports and strenuous exercise while you're sick with infectious mononucleosis.
Medication for mononucleosis
In most cases, mild symptoms will go away by themselves. Some people may take over-the-counter medications, such as NSAIDs, to relieve common symptoms.
If your symptoms don't improve after a few weeks, your healthcare provider can prescribe medication to treat mono symptoms. Because the symptoms of mononucleosis are similar to other illnesses, physicians will typically administer a physical exam and blood test to confirm your diagnosis.
After you've been diagnosed with infectious mononucleosis, your doctor may prescribe:
Medication to treat secondary infections and other complications: Sometimes, a streptococcal (strep) throat can develop alongside mono. Some people may develop a sinus infection or swollen tonsils (tonsillitis). If so, your healthcare provider can provide specific treatment for other health conditions.
Corticosteroids: If you have trouble breathing, you might be experiencing airway obstruction. Your healthcare provider may recommend a corticosteroid injection, such as dexamethasone, to reduce swelling in the throat.
How to prevent mononucleosis
There is no vaccine to protect against infectious mononucleosis. However, it's possible to protect yourself by taking some precautionary measures:
Avoid sharing food, straws, drinks, utensils, inhalers, and cigarettes
Avoid sharing personal items, such as toothbrushes, with an infected person
Avoid close contact, including kissing and sexual contact, with people who are sick
Taking care of your overall health is also important. When your body has the resilience it needs to fight off viruses, you'll be better prepared to cope with illness when exposed.
When to see a doctor for mononucleosis
You should call your doctor if you have infectious mononucleosis and experience:
Trouble breathing or swallowing
Dizziness or fainting
Extreme muscle weakness in the arms or legs
Intense headaches or body aches
Persistent high fever (over 101.5 °F)
Sudden pain in the upper left abdomen
In most cases, a swollen spleen does not cause immediate health problems. However, sharp pain in the upper left part of the abdomen may indicate a rupturing (splitting) of the spleen.
A ruptured spleen is a medical emergency that may require emergency surgery. You should visit the emergency department if you think your spleen may have ruptured.
Related conditions to mononucleosis
According to a 2018 study, the Epstein-Barr virus increases the risk of other major conditions, including:
Inflammatory bowel disease (IBD)
In addition, infectious mononucleosis may be related to other conditions, such as:Reye syndrome
Reye syndrome is a rare but serious illness that causes swelling in the liver and brain. It affects children and teenagers recovering from viral infections, such as mono or the flu.
Aspirin has been linked with this condition, so be sure to exercise caution when giving aspirin to children or teenagers. Talk to your child's doctor for guidance on mono treatment options.Tonsillitis
Tonsillitis refers to the inflammation of the tonsils, leading to swollen glands at the back of the throat. Typically, tonsillitis happens suddenly, and swollen glands can be caused by bacterial or viral infection.
Strep throat
While infectious mononucleosis is a viral infection, strep throat is a bacterial infection. Both conditions present with similar symptoms, but since one is viral and the other is bacterial, they require different treatments. Strep throat can be treated with antibiotics.