About Humira
Humira is considered a TNF alpha inhibitor, which functions by reducing the effects of a substance in the body that can cause inflammation. Like any TNF alpha inhibitor, this medication can only be used for inflammation.
Some conditions that Humira is known to treat include Crohn’s Disease, rheumatoid arthritis, and psoriatic arthritis. Humira is available only by prescription. It is available in a generic formulation under different brand names, including Abrilada, Amjevita, Hadlima, and Hyrimoz.
Humira may be prescribed as an injection via prefilled syringe/pen. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage you are prescribed.
If you are prescribed Humira, be sure to complete the entire course of the TNF alpha inhibitor unless your doctor specifically tells you to stop.
If you don’t complete your prescription, the TNF alpha inhibitor may not fully treat your Psoriatic Arthritis, Crohn’s Disease, or rheumatoid arthritis.
Humira uses
There are nine FDA-approved uses for Humira, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons.
It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.
Rheumatoid Arthritis
Reducing the signs and symptoms, inhibiting the progression of structural damage, and improvement of physical function.
Psoriatic Arthritis
Reducing the signs and symptoms, inhibiting the progression of structural damage, and improvement of physical function.
Juvenile Idiopathic Arthritis
Reduces the signs and symptoms of moderate to severe polyarticular juvenile idiopathic arthritis
Ankylosing Spondylitis
Reduces the signs and symptoms of Ankylosing Spondylitis
Plaque Psoriasis
Treatment of moderate-to-severe chronic plaque psoriasis in patients who are candidates for systemic therapy or phototherapy.
Crohn's Disease
Reduction of signs and symptoms and induction and maintenance of clinical remission in adults with moderate to severe Crohn's disease
Ulcerative Colitis
Treatment of ulcerative colitis unresponsive to immunosuppressants.
Hidradenitis Suppurativa
Treatment of moderate-to-severe hidradenitis suppurativa.
Uveitis
Treatment of noninfectious intermediate, posterior, and panuveitis in adults
Humira side effects
The side effects associated with taking Humira are typically mild. Most Humira side effects are associated with injection site reactions. Humira has some common side effects. They may include:
Redness, bruising, itching, or swelling at the injection site
Increased creatine phosphokinase
Nausea
Abdominal pain
Other side effects, which are less common but might be more severe, could include:Allergic reactions
Blood disorders
Skin reactions
Vascular disorders
You should call your doctor if you notice any of these side effects or develop any other new or concerning symptoms.
How to take Humira
Your pharmacist will be able to give you instructions on how to take your Humira prescription.
Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Humira can come in different forms and doses, so follow the specific instructions on your prescription. It is typically prescribed every two weeks. Some particular instructions may include 40 mg subcutaneously (SC) every 2 weeks.
What to avoid while taking Humira
Humira has 425 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.
Knowing there is a risk of serious infections when taking Humira is essential. Tell your doctor if you experience signs and symptoms of tuberculosis, lupus, or sepsis.
Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Humira.
Some research shows that regular alcohol consumption doesn't impact using Humira. Alcohol may increase the risk of acute liver failure when taking Humira.
Don't administer Humira to bruised, red, tender, or hard skin.
Medication alternatives to Humira
If your healthcare provider prefers to put you on another treatment, they may suggest another adalimumab or a TNF alpha inhibitor in another drug class. Here are some common doctor-recommended alternatives based on your health issue.
Allergic reactions
Methotrexate
Orencia
Remicade
Xeljanz
Rituxan
Humira prescription FAQs
How much does Humira cost?
The average price for Humira is $7,389 for two subcutaneous kits or a month’s supply. This adds up to $84,000 a year for Humira treatment.
What can you not take with Humira?
You should not take Humira with Orencia, Kineret, Remicade, Enbrel, Cimzia, or Simponi. Also, avoid eating raw and undercooked foods, as the risk of severe infections is greater.
When should you not inject Humira?
Humira shouldn't be taken when you have any infection without telling a doctor. This is because Humira causes the immune system not to work as well. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body.
How long can Humira be left out of the fridge?
Humira may be stored at room temperature up to a maximum of 77°F for up to 14 days, with protection from light. After this time, Humira should be discarded.
How can I refill my Humira prescription?
Humira can be filled at any local pharmacy by online doctors or pharmacists.
Who should not take Humira?
Humira should not be taken if the patient has an infection or a compromised immune system.
What happens if I miss a dose of Humira?
Take the missed dose ASAP. Then continue to take your next dose as scheduled. Take only one dose at a time.
What happens if I take too much Humira?
You can call your healthcare provider or local Poison Control Center or seek emergency medical attention immediately.
3 simple steps to request your Humira prescription today

Step 1
Book a Humira prescription request appointment.
You can book a same-day appointment from anywhere.

Step 2
Talk to your medical provider regarding your Humira prescription.
Visit a doctor on your smartphone or computer.

Step 3
Pick up your Humira prescription.
We can send prescriptions to any local pharmacy.
Humira prescription pricing details
How pricing works
To get a new or refill on your Humira prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Humira prescription resources
Sources:
PlushCare is dedicated to providing you with accurate and trustworthy health information.
Humira (official website): "HUMIRA® (adalimumab)." Humira. Accessed on December 5, 2023, at https://www.humira.com/.
FDA (U.S. Food and Drug Administration): "HUMIRA (adalimumab) Injection, for Subcutaneous Use." FDA. Accessed on December 5, 2023, at https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125057s410lbl.pdf.
Mayo Clinic: "Adalimumab (Subcutaneous Route) - Description and Brand Names." Mayo Clinic. Accessed on December 5, 2023, at https://www.mayoclinic.org/drugs-supplements/adalimumab-subcutaneous-route/description/drg-20066817.
Johns Hopkins Arthritis Center: "Adalimumab (Humira)." Johns Hopkins Arthritis Center. Accessed on December 5, 2023, at https://www.hopkinsarthritis.org/patient-corner/drug-information/adalimumab-humira/.
PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.