Astepro nasal spray (generic Azelastine) available online

Astepro (generic Azelastine) is an antihistamine nasal spray available in two strengths: as the over-the-counter medication Astepro Allergy (azelastine HCI) 0.15%, or as the prescription Astepro (azelastine HCl) 0.10% 137 mcg.^{1, 2, 3} The over-the-counter version has a slightly higher dose and sweeter taste.³ 

What is Astepro used for?  

Astepro, in both of its strength levels, is intended to ameliorate symptoms associated with seasonal and perennial upper respiratory allergies, known as rhinitis, that are caused by both indoor or outdoor allergens.^{2, 4} Typical allergens include pet dander, pollen, dust, and mold.5 When these allergens impact your nasal passages and cause you discomfort, Astepro can provide relief.^{1, 5} 

Another commonly used nasal spray to manage allergies is Flonase. Unlike Astepro, which is an antihistamine spray, Flonase is an intranasal steroids (INS) spray that works to relieve allergy symptoms by reducing inflammation.¹ Therefore, while each medication can relieve seasonal or perennial allergies, the mechanisms of action between the two differ. Adults and children 12 and over are generally able to use both at the same time to relieve symptoms, but you should always discuss your treatment plan with your online doctor prior to using Flonase alongside Astepro.⁸ 

Another key difference between Astepro and Flonase is how long they take to work: Astepro typically provides relief within about 15 minutes, while Flonase generally takes a few hours.^{9, 10} The dosing also differs, so it is important to follow your doctor and pharmacist’s instructions for using both nasal sprays.¹¹ 

The side effects caused by Flonase also slightly differ from the ones you can expect from Astepro, and they include nausea, sore throat, and coughing or wheezing.¹¹ Flonase is also not usually recommended for long-term use in children, as the steroid may cause slowed growth.¹²