Aleve (naproxen) prescription available online

If you are suffering from headaches, muscle pain, tendonitis, menstrual cramps, toothaches, or other severe pain, Aleve (naproxen) can help. Get a new prescription or refill of Aleve today.*

Book an appointment

Relieve mild pain and reduce inflammation

Treats muscle aches, menstrual cramps, headaches, and mild fever

Request Aleve in as little as 15 minutes, with or without insurance*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Aleve (naproxen)

Aleve (naproxen) is a nonsteroidal anti-inflammatory drug (NSAID). It helps reduce inflammation and treats mild pain by inhibiting the function of cyclo-oxygenase, an enzyme that triggers the production of prostaglandins.

Aleve can help treat muscle aches, menstrual cramps, headaches, and mild fever. It's also available as a generic medication under different brand names, including Naprosyn.

It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Aleve, complete the entire course of the nonsteroidal anti-inflammatory drug unless your doctor specifically tells you to stop. If you don’t complete your prescription, naproxen may not fully treat your pain. 

Aleve uses

Your PlushCare doctor may prescribe Aleve for any of the following reasons, or other reasons not listed here. Ask your physician if you have questions about why a medication was prescribed.

  • Headaches

    Naproxen is FDA-approved to headaches. It can help treat moderate headaches, migraines without aura, and localized migraine pain.

  • Muscle pain

    Naproxen is FDA-approved to treat muscle pain. It can help relieve moderate muscle pain, inflammation, swelling, and stiffness.

  • Tendonitis

    Naproxen is FDA-approved to treat tendonitis. It can help reduce inflammation and relieve discomfort associated with tendonitis.

  • Toothaches

    Naproxen is FDA-approved to treat toothaches. Nonsteroidal anti-inflammatory drugs can help relieve dental pain by reducing inflammation and relieving discomfort.

  • Menstrual cramps

    Naproxen is FDA-approved to treat menstrual cramps. It works by inhibiting the body's production of prostaglandins, which can contribute to menstrual pain.

Aleve (naproxen) side effects

  • The side effects associated with taking naproxen are typically mild. Individuals taking naproxen report various side effects, and it's important to remember that side effects may vary from patient to patient.

    The side effects of Aleve may include:

    Other side effects, which are less common but might be more severe, could include:

    • Easy bruising/bleeding

    • Hearing changes, such as ringing in the ears

    • Signs of kidney problems

    • Vision changes, such as tunnel vision

    Call your doctor if you notice any adverse effects or develop any other new or concerning symptoms.

How to take Aleve

Your physician will provide you with instructions on how to take Aleve. Be sure to read any labels if using over the counter Aleve or Naprosyn and ask you physician if you have any questions on how to take it.

Aleve can come in different forms and doses, so follow the specific instructions on your prescription.

The dosage or Naproxen or Aleve is typically 220-500mg taken by mouth twice a day. There are other formulation and dosage depends on the reason for use. Your physician should discuss appropriate dosage limits.

What to avoid while taking Aleve

Aleve has several drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications, supplements, and OTC medications. 

Possible drug interactions with Aleve may include:

Naproxen might also interact with certain medical conditions. Please be sure to discuss your complete medical history with your doctor to see if the benefits of naproxen outweigh its risks for your specific case.

Avoid drinking alcohol while taking naproxen. Regular alcohol consumption can increase your risk of abdominal pain and stomach bleeding. If you have black stools or cough up vomit that looks like coffee grounds, seek emergency medical help.

Medication alternatives to Aleve

  • If your healthcare provider prefers to put you on another treatment, they may suggest another nonsteroidal anti-inflammatory drug or pain medication in another drug class.

Aleve prescription FAQs

  • How much does Aleve cost?

    Depending on your pharmacy, a prescription of sixty 500 mg tablets of generic naproxen costs around $34.69 without insurance.

  • How can I refill my Aleve prescription?

    Book a virtual appointment with a board-certified PlushCare doctor to refill your Aleve prescription. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Aleve?

    You should not take Aleve if you've ever had an asthma attack or severe allergic reaction after taking an NSAID. You should also avoid Aleve if you have certain medical conditions, such as:

    • Heart disease, high blood pressure, or diabetes

    • Liver or kidney disease

    • Heart attack, blood clots, or stroke

    • Stomach ulcers

    • Fluid retention

    • Bleeding disorders

  • What happens if I miss a dose of Aleve?

    If you miss a dose of Aleve, take the missed dose as soon as possible. If it's almost time for the next dose, skip the missed dose and return to your regular dosing schedule. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Aleve?

    If you've taken too much Aleve, call your doctor right away. If you experience any adverse events, such as trouble breathing or severe stomach pain, call 911 or seek emergency medical help.

3 simple steps to request your Aleve (naproxen) prescription today 

Step 1: Book an appointment

Step 1

Book an Aleve prescription request appointment.

You can book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Aleve prescription.

You can visit a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Aleve prescription.

We can send prescriptions to any local pharmacy.

Aleve prescription pricing details

How pricing works

To get a new or refill on your Aleve prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.