Xulane birth control patch available online 

If you're interested in pregnancy prevention, Xulane can help. Get a new prescription or refill of Xulane contraceptive birth control patch from a caring, board-certified primary care doctor online.*

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Convenient online Xulane prescriptions

Available as a patch

Estrogen and progestin combined birth control

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Xulane birth control patch

Xulane is a birth control patch that you wear on your skin to prevent pregnancy. Xulane contains two hormones (estrogen and progestin), which are absorbed through the skin. Xulane prevents pregnancy by stopping the ovaries from ovulating and releasing eggs.

Xulane is a type of hormonal birth control prescribed for pregnancy prevention. Xulane is available only by prescription. It is available in a generic formulation under its chemical name, norelgestromin and ethinyl estradiol.

Xulane is prescribed as a birth control patch. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Xulane, ensure you adhere to using the hormonal birth control as directed unless your doctor specifically tells you to stop. If you don’t use your prescription as directed, the prescription birth control patch may not be as effective at preventing pregnancy.

Xulane patch uses

Contraception is the only FDA-approved use for the Xulane birth control patch transdermal system, but it may also be used off-label to treat other conditions. Your online doctor may prescribe it for the following reasons.

It’s also possible that your healthcare professional may prescribe it for other reasons not listed here. Ask your online doctor if you have questions about why a medication is prescribed.

  • Pregnancy prevention

    The Xulane patch is FDA-approved to prevent pregnancy in women with a body mass index (BMI) under 30. Xulane is considered a form of hormonal birth control, which releases estrogen and progestin to lower the risk of pregnancy.

Xulane patch side effects

The side effects associated with taking Xulane are typically mild. Most Xulane side effects are associated with gastrointestinal discomfort.

  • Xulane has some common side effects. They may include:

    • Headache

    • Nausea and stomach pain

    • Breast symptoms, such as soreness and tenderness

    • Unusual vaginal bleeding or menstrual changes, such as spotting between periods

    Other side effects, which are less common but might be more severe, could include:

    • Mood changes

    • Weight gain

    • Sudden shortness of breath

    • Severe headache unlike your usual headaches

    • Yellowing of the skin or eyes (jaundice)

    Call your healthcare professional if you notice any of these side effects, or if you develop any other new or concerning symptoms. The Xulane patch can cause serious cardiovascular side effects, such as blood clots, especially in women with other risk factors such as smoking, high blood pressure, and obesity (BMI > 30).

    The use of Xulane patches is not advised in children under age 18.

How to use the Xulane patch

It's essential to follow the instructions provided by your doctor or the package insert carefully to ensure the Xulane patch is used correctly and effectively. If you have any questions or concerns, speak with your healthcare provider. Here are the steps to use the Xulane patch:

  1. Choose a spot on your skin where you want to apply the patch. It should be a clean, dry area on your abdomen, buttocks, upper arm, or upper torso, but not on your breasts.

  2. Open the foil package and remove the patch. Do not use the patch if the package is already open or the patch is damaged.

  3. Peel off the protective liner and apply the patch to your skin. Press the patch firmly in place with the palm of your hand for about 10 seconds. Before applying the patch, do not apply lotion, oil, or powder to the area.

  4. Wear the patch for one week. On the same day of the week each week, remove the patch and apply a new one to a different area of your skin. Do not use the same spot for at least a week.

  5. Keep the patch on even when you shower, swim, or exercise. If the patch falls off, apply a new one right away. If it has been off for less than 24 hours, you do not need to use a backup method of birth control. If it has been off for more than 24 hours, you should use a backup method of birth control for seven days.

  6. After three weeks of wearing patches, take a week off. During this week, you will have your period. Begin a new cycle by applying a new patch on the same day of the week you started the previous cycle, even if you are still bleeding.

What to avoid while using Xulane

You can always ask your healthcare provider questions or concerns about using Xulane or other medications. Here are some things to avoid while using Xulane:

  • Smoking: Smoking while using Xulane can increase your risk of severe side effects such as blood clots, stroke, and heart attack. If you smoke, talk to your healthcare provider about quitting.

  • Certain medications: Some medications can interact with Xulane, reducing its effectiveness or increasing the risk of side effects. Xulane has 432 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. Possible drug interactions with the Xulane patch include:

    • Certain seizure medications

    • Certain combinations of HIV medications

    • Rifampin and rifabutin

    • St. John’s wort

  • Delaying patch application: Xulane should be applied on the same day each week. If you apply the patch late or miss a dose, your risk of pregnancy may increase. Follow the instructions carefully and set a reminder to help you remember to change the patch on time.

  • Allergic reactions: Some people may be allergic to the adhesive used in Xulane, causing skin irritation or an allergic reaction. If you develop a rash, itching, or swelling, contact your healthcare provider.

  • Pregnancy: Xulane should not be used if you are pregnant or suspect you may be pregnant. If you become pregnant using Xulane, remove the patch and contact your healthcare provider.

Medication alternatives to Xulane

If your healthcare provider prefers to put you on another treatment, they may suggest another birth control patch or hormonal birth control in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Xulane birth control patch FAQs

  • How much does Xulane cost?

    Depending on your pharmacy, Xulane costs around $149 for three patches without insurance. Fortunately, most health insurance plans offer free or low-cost birth control.

  • How can I refill my Xulane prescription?

    To refill your Xulane prescription, book a virtual appointment with one of our top-rated board-certified doctors. After reviewing your medical history, your doctor can send an electronic prescription to your local pharmacy.

  • Do you gain weight on Xulane?

    Weight gain is a possible side effect of the Xulane birth control patch. However, most people don't gain weight when using the Xulane patch.

  • Is Xulane high estrogen?

    Yes, the Xulane patch is a combined hormonal contraceptive that provides a dose of 35 mcg ethinyl estradiol per day. Xulane contains more estrogen than the typical birth control pill.

  • What are the side effects of the Xulane patch?

    Possible side effects of the Xulane patch include:

    • Headache

    • Nausea and stomach pain

    • Mood changes and anxiety disorders

    • Breast symptoms, such as soreness and tenderness

    • Irregular vaginal bleeding, such as breakthrough bleeding

    • Skin irritation around the application site

  • Is Xulane estrogen based?

    Yes, Xulane is estrogen based. Xulane contains two hormones: ethinyl estradiol (an estrogen) and norelgestromin (a progestin).

  • Who should not take Xulane?

    Avoid taking Xulane if you:

    • Smoke and are over 35 years old

    • Have a history of blood clots

    • Have a history of stroke, heart attack, or high blood pressure

    • Have unexplained vaginal bleeding

    • Have gallbladder disease, liver disease (including liver tumors), or kidney disease

    • Have breast cancer, cervical cancer, or any other cancer sensitive to female hormonal birth control methods

    • Have a body mass index (BMI) over 30

  • What happens if I miss a dose of Xulane?

    If you forget to change your Xulane patch for 1–2 days, apply a new patch as soon as you remember. Apply your next patch on your normal patch change day.

    If you forget to change your Xulane patch for more than two days, you may become pregnant. Start a new four-week cycle as soon as possible by applying a new Xulane patch, and use a backup birth control method for the first week of your new patch cycle.

  • What happens if I take too much Xulane?

    If you apply a new patch without removing the old patch, you may experience:

    • Skin irritation at the application site

    • Nausea, vomiting, and bloating

    • Breast symptoms, such as tenderness

    • Weight gain

    • Swelling around your feet and ankles (fluid retention)

    Call your healthcare provider immediately if you notice any adverse side effects.

3 simple steps to request your Xulane patch today 

Step 1

Book a Xulane patch request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your Xulane patch.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Xulane patch.

We can send prescriptions to any local pharmacy.

 Xulane patch pricing details

How pricing works

To get a new or refill on your Xulane prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

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If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.