Xofluza Prescription Online: Uses, Benefits & FAQs
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Xofluza prescription online
Urgent Care Xofluza
Urgent Care Xofluza

Get Xofluza Online for Fast Flu Relief

Speak with a board-certified PlushCare doctor today to get a same-day prescription for Xofluza, an FDA-approved antiviral that helps shorten flu symptoms and speed recovery, all from the comfort of home.*
Reduce flu symptoms in as little as 2–3 days One-time dose treatment for flu symptoms Discuss your symptoms and get a prescription in minutes*
PlushCare content team
Written by PlushCare content team
Dr. Alisha Goodrum
Medically reviewed by Alisha Goodrum, MD
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*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card. PlushCare doctors cannot treat all cases of influenza. Our board-certified primary care physicians can conduct an initial evaluation of your symptoms but may need to refer you to a specialist or for in-person treatment. If you are experiencing life-threatening symptoms, seek emergency medical attention immediately. 
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What is Xofluza?

Xofluza (baloxavir marboxil) is a prescription antiviral medication used to treat the flu (influenza) in adults and children 5 years and older. Unlike other flu treatments that require multiple doses over several days, Xofluza is taken as a single oral dose, making it a convenient option for many patients. 

 

Xofluza works by stopping the flu virus from multiplying in the body. When taken within 48 hours of flu symptoms starting, it can help shorten the duration of illness and reduce symptoms like fever, cough, sore throat, and body aches. 

 

At PlushCare, licensed doctors can prescribe Xofluza during a virtual appointment after evaluating your symptoms and medical history. 

Xofluza Uses

Xofluza is used to: 

  • Treat acute, uncomplicated influenza in people who have had symptoms for no more than 48 hours. 
  • Prevent flu infection (in some cases) after exposure to someone with the flu, especially in household settings. 

 

Xofluza is not a substitute for a flu vaccine. The flu shot is still the best way to prevent getting the flu. However, Xofluza can be helpful if you’ve already been exposed or are starting to feel sick. 

 

Patients who are pregnant, breastfeeding, or have certain health conditions should talk to a doctor before taking Xofluza. PlushCare primary care doctors can review your health status to determine if it’s the right prescription for you. 

Xofluza vs Tamiflu

Understand the difference between Xofluza and Tamiflu

Xofluza

Single oral dose. Can shorten flu symptoms within 2–3 days when taken within 48 hours of onset. May cause diarrhea, nausea, and headaches.

Tamiflu

Taken twice a day for 5 days. Similar symptom relief; may take up to 3 days for full effect. May cause nausea, vomiting, and headaches. Requires multiple doses and consistent scheduling.

Xofluza FAQs

How Quickly Does Xofluza Work?

Most people start to feel better within two to three days after taking Xofluza. It can help reduce flu symptoms faster than no treatment.

Is Xofluza Safe?

Xofluza is FDA-approved and generally well-tolerated. The most common side effects are diarrhea, nausea, and headache.

Can You Get Xofluza Online?

Yes. Through PlushCare, you can book an online doctor’s appointment, discuss your flu symptoms, and get a Xofluza prescription if appropriate, without leaving home.

Do I Still Need a Flu Shot If I Take Xofluza?

Yes. Xofluza treats or prevents active flu infections but does not replace annual flu vaccination.

How Is Xofluza Different From Tamiflu?

Both are antiviral drugs for the flu, but Tamiflu is taken twice daily for five days, while Xofluza is a single-dose treatment. 

3 simple steps to request your Xofluza prescription today

Xofluza appointment online
Step 1

Book a Tamiflu prescription request appointment.

Book a same day appointment from anywhere.
Xofluza Prescription online
Step 2

Talk to our doctors regarding your concerns.

Visit with a doctor on your smartphone or computer.

 

If you have access to an over-the-counter flu test, we recommend taking it before your appointment. A positive test result or symptoms combined with known flu exposure helps our doctors confirm your diagnosis and prescribe Xofluza safely. Your doctor may ask you to complete an at-home flu swab and upload a photo of your test result after your visit. 
Xofluza prescription
Step 3

Pick up your Xofluza prescription.

We can send prescriptions to any local pharmacy.

How pricing works

To get a new Xofluza prescription, join our monthly membership and get discounted visits.

30 days of free membership

  • Same-day appointments 7 days a week
  • Unlimited messages with your Care Team
  • Prescription discount card to save up to 80%
  • Exclusive discounts on lab tests
  • Free memberships for your family
  • Cancel anytime

Paying with insurance

Membership

19.99

First month free

+

Visits

Copay

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

 

We accept these insurance plans and many more:

Humana-Logo Cigna-Logo Aetna-Logo

Paying with insurance

Membership

19.99

First month free

+

Visits

$129

Visit price without insurance

Initial visits are $129.
 
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Sources:

PlushCare is dedicated to providing you with accurate and trustworthy health information.


PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.