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Welcome to your weight management program with PlushCare!

Guiding you through your weight loss journey

Program overview: How It Works

With access to board-certified primary care physicians and program material, here's what you can expect throughout your journey: 

What To Expect With Our Weight Management Program

With access to board-certified primary care physicians, here's what you can expect throughout your journey.

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1st Visit (Today)

Book a visit with a doctor online to discuss weight loss.

During your first visit, your PlushCare doctor will review your medical history and health goals. After your first visit, we recommend completing the following: 

 

  • Complete some lab work – It typically takes 3-5 days for us to receive your lab results.
  • Verify your insurance coverage – Review your options and confirm which medications you qualify for with your insurance.
  • Review this hub for more info – Review the list of weight loss medications and healthy diet & exercise habits available on this page so you can discuss your treatment plan with your doctor. 
How It Works Step 2A
2nd Visit (Within 2 Weeks)

Review your lab results and see which medication may be right for you.

After your second visit, we recommend completing the following: 

  • Submit a Prior Authorization (PA) for insurance coverage – If a PA is needed, It typically takes 1-2 weeks to hear back from your insurance company.   

  • Start your medication – Pick up your prescription and begin treatment.

Prescription-pharmacist
3rd Visit & Beyond (One Month Later)

Follow-up with your doctor monthly and between visits to track progress.

Prescriptions are provided at the doctor’s discretion. If medication is prescribed, it will be sent to your pharmacy of choice. Learn more about what to expect after each visit below.

What to expect after your first visit

Discuss your health history, health goals, and past treatments with your doctor for personalized metabolic health recommendations.

Common weight loss medications

Check with your insurance provider to determine which medications are covered under your plan. If you do not have insurance, or insurance does not cover weight loss medications, we can send Wegovy prescriptions using the Novocare® discount card to NovoCare® Pharmacy or local pharmacies, and prescriptions for Zepbound® vials through LillyDirect. Both of these options allow for significant cost savings on retail price.

 

Please note: Phentermine and Qsymia are controlled substances and cannot be prescribed at PlushCare due to federal law. Learn more about how weight loss medications work.

FDA-approved weight loss medications

The U.S. Food and Drug Administration (FDA) approves several weight loss medicines for treating overweight or obesity: 

FDA-approved for the treatment of Type 2 Diabetes

The following GLP-1 medications are recommended for individuals with Type 2 Diabetes who need to lose weight:

Completing your lab work

After your first appointment, lab work is required to understand your health, determine which medications are safe for you. Labs also allow us to personalize your diet and exercise goals.

  • Which labs are required?

    Labs may include Lipids, CBC, CMP, TSH, HA1C, fasting insulin, height, weight, and blood pressure.
  • How much will these lab tests cost?

    The cost of these labs may differ depending on your insurance coverage. Some insurance plans cover the cost of these labs and some may not. If you elect to pay cash, your insurance for the labs, PlushCare has a discounted cash rate option with Quest Diagnostics and basic weight management labs are $105.  

     

    If you are interested in the discounted cash rate option (i.e. not going through your insurance), please let your physician know that you want to do the discounted cash rate option before they order your labs as you will need to obtain a prepaid lab slip prior to going to the Quest Diagnostics. 

  • Where can I complete my labs?

    All of the lab tests we order through our system default to Quest Laboratory Services. If you need to complete your labs elsewhere, contact our Care Team, and they will send you a signed copy of our lab request to take to any lab. We also have another convenient option, where patients can get their labs done with an at home lab test kit as well. More information regarding at home lab tests are below under At Home Lab Testing. 

  • How do I prepare for my lab tests?

    Please fast for 12 hours before the blood tests. You may drink water, but please avoid black coffee or tea. If you’re taking Biotin, stopping for 3 days before the lab tests is best, as it can change your TSH results.
  • How long after completing my labs will my results be ready?

    Results may take up to 3-5 business days. If you have done your labs and have not heard from us within 5 days, please email or call us to let us know your labs have been done. 

  • What if I’ve recently completed these labs?

    If you have completed all the required labs within the past 2 months, please upload your labs when you check in for your second appointment. 

     

    Learn more about the importance of lab tests for weight management

     

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At Home Lab Testing (An Alternative Lab Testing Option)

You can now enjoy our at-home lab tests for metabolic health that deliver accurate, affordable, and easy testing with the quality and reliability you deserve. Our wide variety of tests includes screening for thyroid disease, insulin resistance, prediabetes, diabetes, high cholesterol, and kidney and liver health. This option is available in all states except New York.

  • What home metabolic health panels do you offer?

    PlushCare offers AST, ALT, Serum Creatinine, Insulin, TSH, Lipid, HbA1C at-home lab testing kits.

  • Who is this available to?

    Our at-home lab tests are available to patients in all 50 states.

  • What is the cost?

    This lab set costs $109 and will be billed to your payment information on file.

  • How long will it take to ship to me?

    It can take approximately 3-5 business days to ship.

  • How long will it take for my lab results to process?

    It can take approximately 5 business days to process.

  • How does PlushCare’s at home testing kit work?

    Unlike in person lab testing where vials of blood are taken from your arm, PlushCare's at home testing kit option collects drops of blood from your fingertip using a small lancet. For a more comprehensive overview on the collection process, here is the at home testing kit instructions that can be found as an insert with each testing kit. 

      

    If you already had your first visit with a physician and you were issued an in-person lab slip but would like to do an at home lab testing kit instead, please reach out to us by sending an email to info@plushcare.com with your information and we can help get this at home testing kit option for you. Insurance does not cover this at home testing kit. If you wish to proceed with our convenient at home testing option, the cost of this lab set is $109 and will be billed to the payment information that we have on file. 

     

    Once your order is sent, additional information regarding your at home testing kit can be found here 

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Verifying your insurance coverage

Contact your insurance company to verify which medication options are covered under your insurance plan and ask if they require prior authorization. Knowing what your plan covers will help you and your doctor identify the best treatment option.

How to find out if you have insurance coverage for weight loss medications:

Insurance companies only cover FDA approved diabetes medications such as Ozempic (semaglutide), Mounjaro (tirzepatide), and Victoza (liraglutide) if you have type 2 diabetes.  

If you do NOT have type 2 diabetes, contact your insurance company to see if if they cover FDA-approved weight loss medications for weight loss treatment. These medications are also FDA approved for weight loss under the following names:

What if I have a BMI of >27 and one weight-related medical condition, or a BMI of >30?

You should ask about the following FDA approved weight loss medications based on your underlying medical conditions:

What if I have Type 2 Diabetes?

You should ask about the following FDA approved diabetes medications with additional weight loss benefits:

Tier changes and their impact on GLP-1 medication costs

In early 2025, certain GLP-1 medications, such as Wegovy® and Zepbound®, have been reclassified by pharmacy benefit managers (PBMs) from Tier 2 to Tier 3. This shift can result in higher out-of-pocket expenses for patients, even when prior authorizations are approved. 

 

Understanding tier changes

Tier 1: Typically includes generic medications with the lowest copayments.  

Tier 2: Often comprises preferred brand-name drugs with moderate copayments.  

Tier 3: Usually consists of non-preferred or specialty medications with higher copayments or coinsurance.  

When a medication moves from Tier 2 to Tier 3, the cost to the patient can increase substantially, sometimes by several hundred dollars per month. 

 

Steps to address increased costs 

Consult Your PBM or Insurance Provider: 

Verify Coverage: Confirm the current tier status of your medication and inquire about any potential changes.  

Cost Implications: Ask about your specific out-of-pocket costs, considering deductibles and coinsurance.  

 

Discuss alternatives with your PlushCare doctor

Wegovy through the Novocare ® mail order pharmacy, or using the Novocare ® discount card at any local pharmacy:  

$499/month for any dose (0.25mg to 2.4mg)

 

Zepbound® Vials via LillyDirect mail order pharmacy:  

$349/month for 2.5 mg vials. 
$499/month for 5, 7.5, and 10 mg vials. 

Your Second Appointment

During your second visit, your doctor will review your lab results, discuss medication options based on your medical conditions and cost, and help you set initial diet and exercise goals. If medications are recommended, your doctor will send a prescription at the end of this visit.

Submitting a prior authorization

  • Can I use insurance for weight loss medication?

    Yes, we are in network with most major insurance providers. 

     

    However, most insurance companies require a prior authorization to be submitted before they will respond with the cost of the medication for you. When your PlushCare physician prescribes the medication, our care team will reach out to your insurer on your behalf. This process can take several business days. Your insurance company typically responds within 1-2 weeks with their decision about medication coverage. If your insurance company denies medication coverage or if you do not have health insurance, you may still purchase the medication at the cash price. 

  • How do I submit a Prior Authorization?

    Insurance companies often require Prior Authorizations (PAs) to cover the high cost of FDA approved weight loss medications such as Saxenda (liraglutide), Wegovy (semaglutide), or Zepbound (tirzepetide). To be as efficient as possible, we submit most requests electronically via Cover My Med.

     

    The information we need to submit your prior authorization is collected during your doctor visit, by getting your lab work done, and by entering your insurance information before your second visit.

     

    The PA process starts automatically once your doctor prescribes medications to treat weight loss or type 2 diabetes. You will receive a confirmation email that your information was received and in the queue. It usually takes 3-7 business days for our team to compile the necessary information to submit your PA, but this can vary. If we need more information from you, our care team will reach out via email.  Please make sure that you check your email regularly, including your spam folder. The process can be delayed if we do not have all the information that we need to submit a complete PA. If you were prescribed a medication that needs a PA and you did not receive a confirmation email from us or if you have a chance in your insurance information, please reach contact our care team at info@plushcare.com.

     

    If you’ve been prescribed a different type of medication and your pharmacy has told you a PA is needed to process the prescription, please call us at (888) 729-0438 or email at info@plushcare.com. You may be asked to fill out a short intake form with information about your insurance and prescription history.

  • What information will be asked from me in order to submit a Prior Authorization?

    You’ll need to provide us with the following information:

    • Name on file with your insurance company

    • Address on file with your insurance company

    • Rx number

    • BIN number

    • PCN number

    • Insurance identification number


    The information you provide must match what your insurance provider has on file. If the information doesn't match, it can lead to medication denials and delays in receiving your medication. Contact your insurance before filling the PA form if needed. 

    If applicable, please include past medication details, relevant lab results and for weight loss medication, you can provide documentation from previous programs. 

  • How do I obtain my RxBIn, PCN, and Group Number?

    These are often listed on your insurance card. If you can't find them there, please log into your health plan website or contact them directly for assistance.

     

    Read more about what to do if your PA has not been submitted

  • Common questions to ask your pharmacy benefits manager (PBM)?

    When checking your insurance coverage for GLP-1 medications, it's important to ask specific questions to get clear and accurate information. Many PBMs do not disclose details unless prompted, so being prepared can help you avoid unexpected denials or costs. 

     

    Coverage & Cost 

    • Does my plan cover [medication name] for weight loss? (e.g., Wegovy, Zepbound) 
    • If not, does it cover any GLP-1 medications for weight management? 
    • What is my copay or out-of-pocket cost for this medication? 
    • Are there any manufacturer savings programs or discounts available? 

     

    Prior Authorization (PA) Requirements 

    • Does this medication require prior authorization? 
    • What medical criteria must be met for approval? 
    • Are there specific lab tests or medical conditions required? 
    • What documentation does my doctor need to submit? 

     

    Step Therapy & Alternatives 

    • Does my plan require step therapy, meaning I must try other medications first? 
    • If so, which medications must I try before qualifying for GLP-1 coverage? 
    • How long must I try alternative medications before requesting approval? 

     

    Weight Loss Program Requirements 

    • Do I need to complete a structured weight loss program before approval? 
    • If so, which programs are accepted? (e.g., Omada, in-person weight management programs) 
    • What proof or documentation is required for program completion? 
  • What happens if my PA is denied?

    If your prior authorization is denied, please find out the reason for the denial. In your follow-up visit with your physician, you can discuss other treatment options. 


    The four most common reasons why medications are denied:


    1. Insurance plan exclusion of all weight loss medications:  
    This means your insurance plan does not cover any weight loss medications or GLP-1 agonist medications.  

     

    2. No history of type 2 diabetes:
    Most insurance companies do not cover FDA-approved for diabetes medications (Victoza, Ozempic®, or Mounjaro® to be used "off label" for weight loss. These same medications are also FDA approved for weight loss but have different names (Saxenda, Wegovy, and Zepbound).  If you have not done so already, the next step is to find out if your insurance covers these FDA approved weight loss medications.  

     

    3. Non-formulary:
    This means that you need to try several medications listed on your insurance company's formulary for your medical conditions during a period of time (often 6 months) with documentation they have not worked for you. Your insurance company will not cover a medication that is not on their formulary. 

     

    4. Additional information:  
    This can mean that your insurance company requires more information, Your insurance company may require an additional specialized test or your insurance company requires proof of a comprehensive diet and exercise program enrollment for a set amount of time (often 6 months) before they will cover a medication. There are other possibilities as well.  You should email any needed documentation to info@plushcare.com. 

  • What happens if I cannot find or afford my medication?

    There are a few alternative options you can take if your medication is out of stock or your medication is not covered by your insurance:

     

    • Use manufacturer coupons when your insurance denies your medication. Please check the website of the manufacturer of the medication that was denied by your insurance. Eligibility criteria and savings amounts may differ depending on the manufacturer of the medication.

    • Discuss other treatment options with your doctor.  When we know why your medication is denied your doctor can help you understand other treatment options and help you decide on the next best steps

    •  

      Ask for prescriptions for Zepbound® vials through LillyDirects mail-order pharmacy.

    • Ask for prescriptions for Wegovy® through NovoCare® Pharmacy or to any local pharmacy using the Novocare ® discount card. 
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Medication Shortages FAQs

  • If I cannot find the next dose of medications, can I skip to a higher dose of medication?

    "For example, if I am on Zepbound 5 mg, and my pharmacy does not have the 7.5mg in stock, can I skip to 10 mg dose?"

     

    The FDA has approved a standard titration of this medication that requires taking each dose for at least a month before increasing to the next dose. This titration is designed to minimize side effects such as nausea, vomiting, dehydration, diarrhea, dehydration, and headaches.  Increasing the dose of medication too quickly can also cause severe calorie restriction. For your safety, we recommend following the FDA approved titration of the medication rather than skipping multiple doses of the medication. However, it is always safe to reduce to a lower dose.   As always, please discuss your individualized treatment plan with your doctor to help navigate the shortages. 

  • My dose of medication is not available, can I inject myself twice with a lower dose to add up to a higher dose?

    "For example, if my 10 mg dose of Zepbound is not available–can I just take 2 injections of the 5 mg dose instead?"

     

    While this seems like a reasonable solution, unfortunately insurance companies will only cover one pen of medication per week.  Giving two injections per week will use twice the amount of medication and you will run out of medication after two weeks.  You will then have to wait an additional two weeks before you can get medication again. It is better for your weight loss to stay on a lower dose of medication each week than start and stop a higher dose of medication. 

  • Can I use a higher dose and just pull the needle out early to get a lower dose?

    No. These pens are set to deliver a set amount of medication. You cannot control the amount of medication given if you remove the pen while it is injecting. You could waste the entire dose of medication or get a high amount of medication. These medications help you lose weight better if you take the same amount of medication every 7 days.  

  • Can I break open the pen and use a syringe with a needle to get lower doses?

    No. This is not safe. The pens are designed to keep the medication sterile and safe to inject.  Once the pens are open, the medication is no longer reliably sterile or safe to inject. 

  • Can you send my prescription to another country?

    Unfortunately, we cannot send prescriptions outside the U.S.  

  • If I find another pharmacy that has the dose that I need, how can I move my prescription over to that other pharmacy?

    You can call either the original pharmacy or the new pharmacy and ask to move the prescription.  There's no need to make another appointment with your doctor unless there is an issue with the prescription.

  • If I have been getting my prescriptions from a different service or provider, can I continue taking the dose that I already am at or start my titration from my current dose?

    If you have been receiving your prescriptions for weight loss medications from a different service or provider and would like to continue your weight loss journey with us, we'll be more than happy to help! We do require lab work prior to starting these weight loss medications so that we can understand your metabolic health, help determine which medication is best, and make sure that medications are safe. Once you have done or sent in your recent labs, please book a follow-up visit with your doctor to discuss your labs and determine your long term treatment plan. 

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Common Weight Loss Medication FAQs

  • How is the medication typically prescribed?

    This medication is started at the lowest possible dose. The medication dose is slowly increased with the guidance of your physician to the lowest dose that is most effective for weight loss. 

     

    DO NOT increase the dose of medication on your own or start at higher doses than what was recommended. Please read the package instructions and/or go to the company website for a video on how to give the injections.

  • I'm worried because the ice pack in my medication shipment melted during transit. Is my medication still safe and effective?

    The medication remains safe and effective even if the ice melts during transit. As temperatures rise, it is common for ice packs to melt during the shipping process. The purpose of the ice pack is to maintain a stable environment inside the box. Upon receiving your medication, please store it in the refrigerator as recommended. 


    For any issues regarding medication administration issues (i.e. what happens if the medication is stored improperly, vial or pen malfunction, etc., please reach out to your pharmacist and/or the manufacturer (Novo Nordisk, Eli Lilly).

  • What if I experience side effects?

    Common side effects most commonly include feeling full easily, upset stomach, acid reflux, nausea, vomiting (especially with eating too much), burping, gas, constipation, diarrhea, headache, fatigue, and depression. It is very important to stay hydrated while on these medications because dehydration can cause kidney damage. Side effects may disappear during treatment as your body adjusts. You should never have abdominal pain, vomiting and inability to hydrate, or dark urine while on these medications.  You should never feel depressed or have thoughts of wanting to hurt yourself.

    If you experience any serious side effects, such as allergic reactions, abdominal pain, inability to stay hydrated, depression and thoughts of not wanting to be alive please seek emergency medical attention right away by calling 911.

  • How can I help decrease side effects at home?

    GLP-1 medications can slow the digestive process and can cause a feeling of fullness and nausea. If you think you feel full, stop eating instead of taking another bite. Avoid high fat foods as they digest slowly.

     

    • If you feel full and nauseated: 

      • Try eating smaller meals. If you think you feel full,stop eating instead of taking another bite. Avoid high fat foods as they digest slowly.

      • Eat small portions of lean protein throughout the day like chicken or turkey and high fiber carbohydrates such as vegetables

      • Sip on broth or clear soups.

      • Sit up after you eat for 30 min to one hour. Don’t immediately lie down after eating.

    • If you have acid reflux and bloating: 

      • These symptoms will often improve with antacids like famotidine or omeprazole taken 30 min before eating. Avoid TUMS as that can worsen constipation. If these symptoms persist for longer than 2 weeks or are worsening please see your doctor.

    • If you have constipation:

      • Fiber supplements, a high-fiber diet, hydration, and daily activity can help avoid constipation. You develop constipation, take Miralax and/or senna once daily as needed to have a daily bowel movement.

    • Although rare, GLP-1s can lower your blood sugar:

      • Symptoms of low blood sugar can include lightheadedness, fatigue, sweating, feeling weak, shaky, rapid heartbeat, or headaches. If you have low blood sugar, keep 15g of a sugar replacement on you (e.g. 1/2 cup of juice, 1 tablespoon of sugar, or 8 hard candies). If symptoms do not improve or worsen, repeat and seek medical attention. Do not drive if you have low blood sugar or symptoms of low blood sugar.

  • How can I treat symptoms of low blood sugar?

    If you have symptoms of low blood sugar or documented low blood sugar, raise it by following the 15-15 rule. Take 15g of carbs (e.g. 1/2 cup of juice, 1 tablespoon of sugar, or 8 hard candies) and recheck your blood sugar in 15 minutes.


    If your symptoms have not improved or your blood sugar has risen, repeat the 15g of carbs and seek medical care. DO NOT drive or operate machinery if your blood sugar is low or you have symptoms of low blood sugar. It’s important to talk to your doctor and let them know that you are having low blood sugars.

  • What can make my nausea or gastrointestinal symptoms worse?

    • Avoid Fatty/greasy foods if you have nausea

    • Avoiding alcoholic beverages

    • Avoiding caffeine, acidic foods, and spicy foods

    • Avoid dairy products if you are lactose sensitive

    • Avoid diet drinks/sugarless gum/candies containing sweeteners (e.g. sorbitol, mannitol, and xylitol), fructose, and sometime fruits (apples, peaches, pears) can make GI symptoms worse

  • When should I call a doctor?

    Please stop the medication and follow up with your doctor or seek immediate medical care if you experience any of the following:

    • Fever

    • Abdominal pain of any kind

    • Nausea lasting more than 48 hours

    • Vomiting or diarrhea with dark urine, light-headedness, or dehydration

    • Dark urine and not able to hydrate

    • Thyroid tenderness or pain

    • Depression or suicidal thinking

    • Allergic reaction

  • Do I need to buy separate pen needles with my medication?

    Liraglutide (Victoza® or Saxenda®) requires 32 gauge pen needles. These are available over the counter and, like other over the counter medications, not always covered by insurance. Sometimes a prescription is helpful to cover the cost. 

     

    Wegovy®, Ozempic®, Zepbound ®, and Mounjaro® are pens that come with their own needles.  Zepbound® vials offered at a discount through LillyDirect come in vials with needles and syringes. 

  • If I am using a medication that uses pen needles or syringes with a needle, how do I dispose of them?

    After administering, discard the needle in a sharps container. If you don't have a sharps container, you can use a hard-sided container with a lid, such as a hard-sided detergent bottle. Ensure the container is well sealed before disposal. For your safety, be sure your disposal container is no more than 2/3 full at all times. Once you are ready to dispose of your sharps container, please take it to your local sharps container disposal center.

     

    Safe Needle Disposal is a great resource to help find a sharps container disposal center around you.

  • What do I do if I want to get pregnant or am breastfeeding?

    DO NOT take weight loss medication if pregnant or planning on becoming pregnant or nursing. Please speak with your doctor if you are pregnant or plan on becoming pregnant.
  • What if I’m on other medications to lower my blood sugar or blood pressure?

    Sudden changes in blood pressure and blood sugar are common when people lose weight or take medications for weight loss.

    Please monitor your blood sugar/blood pressure and talk to your doctor if you experience any of the following:

    • Unusual fatigue

    • Weakness

    • Lightheadedness (especially when standing up)

    • Dizziness

    • Nausea

    • Difficulty concentrating


    The 15-15 Rule: 
    If you have symptoms of low blood sugar or documented low blood sugar, take 15g of carbs (e.g. 1/2 cup of juice, 1 tablespoon of sugar, or 8 hard candies) and recheck your blood sugar in 15 minutes.  

    If your symptoms have not improved or your blood sugar has risen, repeat the 15g of carbs and seek medical care.  DO NOT drive or operate machinery if your blood sugar is low or you have symptoms of low blood sugar. It’s important to talk to your doctor and let them know that you are having low blood sugars.

  • What is my weight medication dosage isn’t available at the pharmacy?

    If your weight medication dosage isn’t available at the pharmacy, your pharmacy should be able to find another location in your area that has your dosage. Many major pharmacies have online support for transferring across their locations. Have your insurance info (if applicable), the current pharmacy name, address, and phone number on hand, and they’ll handle the rest.

     

    If you’re still having trouble making the transfer, contact our Care Team and we can help.

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Your third appointment

After starting treatment, you’ll meet with your doctor monthly to discuss your progress, adjust medications as needed, and set new diet and exercise goals. Continue to check in with your health coach regularly in between doctor visits.

 

We're excited to help you take the first steps to live a longer, healthier, and happier life. 

Sources:

PlushCare is dedicated to providing you with accurate and trustworthy health information.

 

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.