Qelbree (viloxazine) online: non-stimulant ADHD medication

While effective for many, stimulant medications can cause side effects like insomnia, decreased appetite, and potential for abuse. It’s important to note that stimulants are also controlled substances and cannot be prescribed by PlushCare doctors.

As a non-stimulant, Qelbree works differently by modulating norepinephrine without acting on dopamine. Both Qelbree and stimulant medications can effectively manage ADHD symptoms. However, every individual may respond differently to a medication.

Your doctor will help you decide which medication is best for you, depending on your medical history, tolerance to side effects, and specific symptoms. If you have questions about ADHD medications, scheduling a virtual doctor's appointment with one of our board-certified primary care physicians is easy.

Qelbree vs. Strattera (atomoxetine)

Qelbree and Strattera are both non-stimulant medications for ADHD. While both Qelbree and Strattera are selective norepinephrine reuptake inhibitors, Qelbree has an extended-release mechanism, and Strattera has an immediate-release mechanism. Both medications share common side effects, such as nausea, vomiting, and tiredness. Some studies show that Qelbree may take effect sooner than Strattera, but there is still much research to be done comparing the two drugs.

Qelbree comes in an extended-release form, so it is taken just once a day. Strattera may be taken once or twice daily, depending on the recommended dose. Qelbree can be taken out of the capsule and added to pudding or applesauce, making it easier for those with trouble swallowing capsules. Strattera must be taken in capsule form.

Qelbree vs. Adderall

Adderall is a stimulant medication that is a common and extremely effective treatment for ADHD. As a stimulant, Adderall is a controlled substance that comes with a risk of abuse. Adderall contains a mixture of different forms of amphetamine and dextroamphetamine.

Qelbree, as a non-stimulant medication, can be an effective alternative for ADHD patients who are not suitable candidates for Adderall or other stimulant medications. It is important to note that our doctors do not prescribe controlled substances, such as Adderall.

Qelbree vs. Vyvanse (lisdexamfetamine)

Both drugs are effective in treating symptoms of attention deficit hyperactivity disorder. Vyvanse is a long-acting amphetamine-based stimulant, whereas Qelbree is a non-stimulant drug.

Non-stimulant ADHD medications like Qelbree are effective options when stimulant drugs aren’t a good choice. In some patients with ADHD, stimulant medications either don't work or cause intolerable side effects. Stimulant medications might also make other disorders, such as anxiety, worse. There’s also the risk of stimulant drugs being abused, which is especially concerning in patients with a history of substance abuse. Our doctors at PlushCare do not prescribe Vyvanse or other controlled substances.

Qelbree vs. Ritalin

Ritalin (methylphenidate) is a type of stimulant medication for ADHD. Ritalin is an effective drug in many ADHD patients and works better in some cases than amphetamine-based ADHD treatments, such as Adderall. Our doctors at PlushCare do not prescribe controlled substances, such as Adderall and Ritalin.

Like all stimulants, Ritalin carries the potential side effects and risks of a controlled substance. As a newer non-stimulant medication, Qelbree offers an effective alternative to treat ADHD.

Qelbree and Lexapro (escitalopram)

Qelbree and Lexapro increase serotonin levels in the brain using different pathways. Qelbree is an SNRI, and Lexapro is an SSRI. Used together, they can cause a life-threatening condition called serotonin syndrome. Qelbree is mainly used for ADHD, while Lexapro is used as an antidepressant.

Qelbree and Prozac (fluoxetine)

Similar to Lexapro, Prozac (fluoxetine) is an SSRI commonly used as an antidepressant. While these two drugs haven’t been studied in combination, combining an SNRI drug like Qelbree with an SSRI like Prozac also carries the risk of serotonin syndrome, which can be life-threatening. While Qelbree may be prescribed with Prozac in specific cases, it’s critical to talk to your doctor about any potential drug interactions and treatment alternatives.

Allergic reactions

Rarely, Qelbree could potentially trigger a severe allergic reaction, with symptoms such as rash, itching, or swelling, particularly in the face, tongue, or throat.  Other potential side effects to watch out for are severe dizziness and difficulty breathing. Get emergency medical help immediately if you notice these potentially life-threatening symptoms.

Some side effects may subside over time as the body adjusts to the medication, while others may worsen. As with any medication, always talk to your doctor right away if you notice any concerning side effects or reactions.

Black box warning: increased risk of suicidal thoughts

There’s an increased risk of suicidal thoughts or behavior in people using Qelbree, particularly in the initial phase of treatment or when doses are adjusted. This risk has been reported in all age groups, including children, adolescents, and young adults.

Anyone beginning treatment with Qelbree or encountering dosage changes should be closely monitored for any signs of unusual changes in behavior, thoughts of self-harm, or suicidal tendencies. If any concerning symptoms arise, seek immediate medical attention right away.

Mania or hypomania in patients with bipolar disorder

Using Qelbree may increase the risk of inducing manic or hypomanic episodes, especially in patients with a pre-existing diagnosis of bipolar disorder. Careful assessment is particularly important for anyone with a history of bipolar disorder.

A prescribing doctor will thoroughly evaluate patients for a history of bipolar disorder or any signs of manic or hypomanic symptoms before prescribing Qelbree. If any such symptoms occur during treatment, seeking prompt medical attention is critical.

Drowsiness or fatigue

Qelbree may also cause drowsiness or a general sense of tiredness or lack of energy. Be cautious when performing tasks or doing things requiring attention until you know how this medication affects you. Don't drink alcohol while taking this medication because it can make sleepiness and dizziness worse.

Pregnancy and breastfeeding

Qelbree may cause harm to a developing fetus and is not recommended for use by women who are pregnant or may become pregnant. It is not known if Qelbree can enter breast milk, therefore the risks and benefits of treatment while breastfeeding need to be discussed with your doctor.

Liver interactions

Periodic monitoring of liver function is advisable during Qelbree treatment. Any signs of liver problems, such as persistent nausea, vomiting, or jaundice, should be reported to your doctor immediately.

Drug and supplement interactions

Qelbree is a relatively new drug and hasn’t been completely studied in terms of interactions, so it’s imperative to inform your doctor about all medications, including prescription and over-the-counter drugs, as well as herbal supplements.

MAOIs

Avoid taking Qelbree in combination with monoamine oxidase inhibitors (MAOIs) due to potential interactions. A 14-day gap is recommended when transitioning between Qelbree and MAOIs to prevent adverse effects.