Nexplanon (etonogestrel implant) prescription available online

If you're interested in pregnancy prevention, Nexplanon can help. Connect with a board-certified doctor online to discuss your birth control implant options and get a referral to a specialist for insertion, if needed.*

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Set-it-and-forget-it birth control option

Available as a contraceptive implant

Nexplanon consultations available online*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Nexplanon 

Nexplanon is a birth control implant, which releases the hormone progestin into your body to prevent pregnancy. Nexplanon is a tiny, thin rod that is inserted into your upper arm by a healthcare professional.

Like other hormonal contraceptives, the Nexplanon implant is used to prevent pregnancy. Nexplanon is available only by prescription. It is available in a generic formulation as well as under different brand names, including Implanon.

Nexplanon may be prescribed as a contraceptive implant. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation prescribed.

Nexplanon is a set-it-and-forget-it birth control, and the implant offers pregnancy protection for up to five years. If you decide you want to get pregnant, your fertility will return to normal soon after implant removal.

Nexplanon uses

There are several FDA-approved uses for Nexplanon, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe hormonal birth control for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Pregnancy prevention

    The Nexplanon implant is FDA-approved to prevent unintended pregnancy. Because Nexplanon helps prevent untended pregnancy, it can also help lower your risk of ectopic pregnancy.

    It releases progestin, which thickens your cervical mucus to stop sperm from reaching your egg. Progestin also stops eggs from leaving the ovaries (ovulation), which prevents fertilization.

Nexplanon side effects

  • The side effects associated with taking Nexplanon are typically mild. Most Nexplanon side effects are associated with spotting.

    Nexplanon has some common side effects. They may include:

    • Changes in your bleeding pattern, such as spotting

    • Nausea

    • Mood changes, such as depressed mood

    Other side effects, which are less common but might be more severe, could include:

    • Headaches

    • Weight gain

    • Breast pain

    You should call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. The use of Nexplanon in children under age 18 is not advised.

How to take Nexplanon

Your pharmacist will provide you with instructions on how to take your Nexplanon prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Your Nexplanon implant will be inserted during a visit to your healthcare provider's office. Insertion is a minor surgical procedure and only takes a few minutes.

During the procedure, you'll lie on your back with your upper arm bent at the elbow. Then, your healthcare provider will inject a local anesthetic into your arm and use an applicator to insert the contraceptive implant beneath your skin.

Your healthcare provider will cover the area with a bandage. It's normal to experience some bruising, pain, or bleeding at the insertion site.

What to avoid while taking Nexplanon

Nexplanon has 216 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with the Nexplanon implant include:

  • Certain antidepressant medications, including Cymbalta (duloxetine) and Lexapro (escitalopram)

  • St. John's Wort

  • Certain antibiotic medications

It's safe to drink alcohol with Nexplanon. Avoid smoking, especially if you're older than 35 years of age, as it can increase your risk factors for serious cardiovascular events.

Medication alternatives to Nexplanon

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another hormonal birth control or birth control method in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Nexplanon prescription FAQs

  • How much does Nexplanon cost?

    Depending on your pharmacy, the Nexplanon implant costs between $0 and $1,300 without insurance. Implant removal can also cost between $0 and $300.

    Fortunately, birth control implants are free or low cost with most health insurance plans, Medicaid, and other federally funded programs.

  • How can I refill my Nexplanon prescription?

    To refill your Nexplanon prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your medical history, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Nexplanon?

    Avoid using Nexplanon if you have certain medical conditions, such as:

    • A history of heart attacks, strokes, or severe blood clots

    • Deep vein thrombosis (DVT)

    • A history of hormone-related cancer, such as breast cancer

    • Undiagnosed abnormal genital bleeding

    • Liver disease or liver tumors

    • High blood pressure

  • What can you not do with Nexplanon?

    Avoid lifting heavy objects or exercising strenuously for a few days after your implant. External forces can cause broken or bent implants, which may move away from the insertion site.

    If you feel like your implant has bent, contact your healthcare provider. Removal of the implant may be necessary.

  • How long does it take for your body to regulate Nexplanon?

    If your doctor inserts the implant after the fifth day of your period, it can take up to seven days for Nexplanon to effectively prevent pregnancy.

  • What should you not do before getting Nexplanon?

    Avoid having unprotected sex for at least three weeks before your insertion appointment. If you're using other birth control options, such as an oral hormonal contraceptive method, continue using them consistently until your appointment.

  • Why do you have to wait 7 days after Nexplanon?

    After getting the Nexplanon implant, you'll need to use a backup birth control method or abstain from sex for seven days. This gives the Nexplanon implant time to start working properly.

  • What happens if I miss a dose of Nexplanon?

    Because the Nexplanon implant is inserted by your healthcare provider, you're unlikely to miss a dose.

  • What happens if I take too much Nexplanon?

    Because the Nexplanon implant is inserted by your healthcare provider, you're unlikely to overdose.

3 simple steps to request your Nexplanon prescription today

Step 1

Book a Nexplanon prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Nexplanon prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your Nexplanon prescription.

We can send prescriptions to any local pharmacy and can refer you to a local specialist for implant insertion.

Nexplanon prescription pricing details

How pricing works

To get a new or refill on your Nexplanon prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.