Annovera ring for birth control - prescription online 

Annovera is a long-lasting, procedure-free birth control ring that lasts a year. Get a new prescription or refill of Annovera from a board-certified doctor online.*

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Discreet and confidential birth control consultations

FDA-approved to prevent pregnancy

Vaginal birth control ring with easy insertion and removal

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Annovera vaginal ring

Annovera is a vaginal ring used for birth control that contains two female hormones, segesterone acetate and ethinyl estradiol, which are slowly released into the vagina.

Annovera ring is FDA-approved to prevent pregnancy and is available only by prescription. It is available in a generic formulation under different brand names, including the ethinyl estradiol vaginal system (vaginal ring).

Be sure to use the ring exactly as prescribed by your doctor. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Annovera, complete the full course of hormonal birth control unless your healthcare provider specifically tells you to stop. If you don’t complete your prescription, the hormonal birth control may not be as effective in preventing pregnancy.

Annovera uses

There is one FDA-approved use for Annovera, but it may also be used off-label to treat other conditions. Your online healthcare professional may prescribe it for the following reasons.

It’s also possible that healthcare professionals may prescribe Annovera for other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.

  • Pregnancy prevention

    Annovera is FDA-approved to prevent pregnancy. Annovera, a combination hormonal contraceptive, is a reusable ethinyl estradiol vaginal system that can be used for up to one year.

Annovera ring side effects

  • The side effects associated with taking Annovera are typically mild. Most Annovera side effects are associated with gastrointestinal discomfort. Annovera has some common side effects. They may include:

    • Nausea, vomiting, and stomach pain

    • Breast tenderness

    • Irregular vaginal bleeding

    • Genital itching or vaginal discharge

    • Urinary tract infection (UTI)

    Other side effects, which are less common but might be more severe, could include:

    • Toxic shock syndrome

    • Signs of blood clots

    • Very high blood pressure

    You should call your doctor if any adverse effects occur, or if you develop any other new or concerning symptoms. The use of Annovera is not advised in children under the age of 18.

How to use Annovera

Your pharmacist will provide you with instructions on how to take your Annovera prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Annovera can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The vaginal ring should be inserted into your vagina and left in for 21 days in a row. After 21 days, remove Annovera for seven days. This will allow your body to have a menstrual period.

Avoid leaving the Annovera ring out for over two hours during your 21-day cycle. Annovera birth control will not effectively prevent pregnancy if you only wear it during intercourse.

What to avoid while using Annovera birth control ring

Annovera has 433 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Annovera include:

  • St. John's wort

  • Antifungal medicine

  • Antiviral medicine used to treat HIV/AIDS or hepatitis C

  • Blood pressure medication

  • Thyroid medicine

  • Venous thrombotic diseases

It is safe to drink alcohol while using Annovera birth control. However, you may need to avoid drinking grapefruit juice while taking Annovera with certain drug combinations. Ask your healthcare provider for medical advice.

Avoid using oil-based vaginal products, such as creams and gels, while using Annovera. Instead, use water-based lubricants. Annovera does not protect against sexually transmitted infections or diseases.

Medication alternatives to Annovera

If your healthcare provider prefers to put you on another treatment altogether, they may suggest other hormonal birth control methods in another drug class. Here are some common doctor-recommended alternatives based on your reproductive health issue:

Annovera birth control ring FAQs

  • How much does Annovera cost?

    Depending on your pharmacy, the Annovera vaginal ring costs around $2,320 for one ring without insurance. Fortunately, birth control is free or low-cost with most health insurance plans.

  • How can I refill my Annovera prescription?

    To refill your Annovera prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your medical history, your doctor can send an electronic prescription to your local pharmacy.

  • What type of birth control is Annovera?

    Annovera is a hormonal birth control method. The Annovera ring releases segesterone acetate and ethinyl estradiol to prevent pregnancy.

  • Is Annovera covered by medical?

    Yes, Annovera birth control and other birth control methods are free or low-cost with health insurance.

  • What company makes Annovera?

    Annovera is made by TherapeuticsMD.

  • What is the difference between Annovera and NuvaRing?

    Annovera and Nuvaring are both ethinyl estradiol vaginal systems. However, they release different forms of progesterone. Annovera contains segesterone acetate, while Nuvaring contains estonogestrel.

  • Who should not take Annovera?

    Avoid taking Annovera birth control if you have certain health conditions, such as:

    • Undiagnosed abnormal uterine bleeding

    • Uncontrolled high blood pressure, heart problems, or coronary artery disease

    • Liver disease or liver tumors

    • Hormone-related cancer, such as breast cancer

    Avoid using a combination hormonal contraceptive if you smoke cigarettes, are over 35, or have a body mass index (BMI) over 29. Do not use Annovera birth control if you're pregnant or planning to become pregnant.

  • What happens if I miss a dose of Annovera?

    Call your healthcare provider if you're off schedule or if you have abdominal pain or trouble removing your vaginal ring.

  • What happens if I take too much Annovera?

    If you've taken too much Annovera, call your doctor. An overdose may cause headache migraine nausea vomiting or vaginal bleeding.

3 simple steps to request your Annovera prescription today 

Step 1: Book an appointment

Step 1

Book an Annovera prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Annovera prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your birth control.

We can send prescriptions to any local pharmacy.

Annovera prescription pricing details

How pricing works

To get a new or refill on your Annovera prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.