Flonase (fluticasone) prescription available online

Our doctors are here to help. If you are suffering from seasonal or year-round nasal allergy symptoms, Flonase can help. You can get a new prescription or refill of Flonase today.*

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Ease year round or seasonal allergy symptoms

Available by nasal spray

Save up to 46.86% on Flonase with RX discount card*

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Flonase 

Flonase (fluticasone) is a corticosteroid medication used to treat an overactive immune response from various health conditions, including allergic reactions, asthma, and nasal polyps. It works by suppressing the immune system and reducing inflammation.

Fluticasone is available over the counter or by prescription. It's available as a generic medication under different brand names, including fluticasone.

Flonase may be prescribed as a nasal spray. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Flonase, be sure to complete the full course of the corticosteroid unless your doctor specifically tells you to stop. If you don’t complete your prescription, Flonase may not fully treat your symptoms.

Flonase uses

There are several FDA-approved uses for fluticasone propionate nasal spray, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe Flonase nasal spray for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Allergy symptoms

    Flonase nasal spray is FDA-approved for hay fever and allergic rhinitis symptoms, including runny nose, watery eyes, and itchy nose. Flonase reduces irritation and inflammation inside the nasal cavity and suppresses the body's immune response to allergens.

  • Nasal polyps

    Fluticasone propionate nasal spray is FDA-approved to treat nasal polyps. The FDA has approved XHANCE, a nasal spray that enters further into the nasal passages than typical nasal sprays, to treat growths in the nasal cavity.

  • Asthma

    Oral fluticasone propionate inhalation is FDA-approved to treat asthma. Fluticasone propionate can help improve lung function, prevent difficulty breathing, and reduce chest tightness caused by asthma.

Flonase side effects

  • The side effects associated with taking Flonase are typically mild. Individuals taking Flonase report a variety of side effects, and side effects may vary from patient to patient.

    Some common side effects of Flonase include:

    • Skin rash and irritation

    • Burning or itching

    • Lightheadedness

    • Nausea or vomiting

    • Throat irritation

    • Coughing

    • Headaches

    • Nosebleeds

    Other side effects, which are less common but might be more severe, could include:

    • Sinusitis

    • Severe asthma or shortness of breath

    • Inflammation in the upper respiratory tract

    • Bronchitis

    • Fungal infections

    You should call your doctor if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of Flonase is not recommended for children younger than the age of 4, as it may slow children's growth.

How to take Flonase

Your pharmacist will provide you with instructions on how to take your Flonase prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

For adults, the FDA recommends using two sprays (50 mcg/spray) in each nostril once per day. For children aged 4 years and older, the FDA recommends using one spray (50 mcg/spray) in each nostril once per day. Children should use Flonase for the shortest amount of time necessary to achieve symptom relief.

If your symptoms are still present after six months of daily use, consult your doctor or pharmacist.

What to avoid while taking Flonase

Flonase has several drug interactions. Don’t change taking flonase without checking with your healthcare professional or pharmacist. That includes other medications, supplements, and over-the-counter medicines.

Some possible drug interactions with Flonase include:

You can drink alcohol while using fluticasone nasal spray and don't usually need to avoid particular foods.

Medication alternatives to Flonase

If your healthcare provider prefers to put you on another treatment, they may suggest another allergy medication or corticosteroid in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • Allergies

    Zyrtec (Cetirizine)

    Nasacort (triamcinolone)

    Afrin (oxymetazolin)

  • Nasal polyops

    Rhinocort (budesonide)

    Nasonex, Asmanex HFA (mometasone)

    Nasacort (triamcinolone)

  • Asthma

    Alvesco (ciclesonide)

    Singulair (montelukast)

    Serevent (salmeterol)

Flonase prescription FAQs

  • How much does Flonase cost?

    Depending on your pharmacy, prescription Flonase costs approximately $17.44 for a 9.9 mL bottle of 50 mcg/ACT nasal spray without health insurance. Fortunately, generic brands, such as fluticasone, offer an affordable alternative.

  • How can I refill my Flonase prescription?

    To refill your Flonase nasal spray prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Flonase?

    If you have a weakened immune system, chronic health condition, or are currently taking another corticosteroid, talk to your doctor about Flonase. You should also tell your doctor if you have a medical history of:

    • Sores or ulcers inside your nose

    • Eye problems, including glaucoma or cataracts

    • Liver disease

    • Diabetes

    • Any type of infection (bacterial, fungal, viral, or parasitic)

  • What happens if I miss a dose of Flonase?

    If you miss a dose of Flonase, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much Flonase?

    If you've taken too much Flonase, call your doctor right away or call the Poison Control Center at 1-800-222-1222.

    An overdose of Flonase is not expected to produce life-threatening symptoms. However, long-term use of steroid medicine can cause eye problems, body fat changes, menstrual problems, and other health issues.

3 simple steps to request your Flonase prescription today 

Step 1: Book an appointment

Step 1

Book a Flonase prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Flonase prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Flonase prescription.

We can send prescriptions to any local pharmacy.

Flonase prescription pricing details

How pricing works

To get a new or refill on your Flonase prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.