Get an EpiPen (epinephrine injection) online, quickly and affordably

EpiPen delivers prompt, life-saving treatment when every second counts. Don't wait for an emergency. Book an appointment with our board-certified doctors today to secure your EpiPen prescription and be prepared for unexpected, life-threatening allergic reactions.*

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Easily portable for life-threatening emergencies

Have peace of mind, wherever you go

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Major cost-savings, with or without insurance

*If you are currently having symptoms of an emergency allergic reaction, call 911 and seek medical care immediately. Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how to save up to 42% on EpiPen with our prescription discount card.

What is EpiPen, and how does it work?

An EpiPen is an injectable form of epinephrine, your emergency response to anaphylaxis, a life-threatening allergic reaction. It rapidly reverses symptoms by:

  • Constricting blood vessels

  • Relaxing airway muscles making it easier to breathe

  • Stimulating the heart

EpiPens counter the body's emergency reactions to allergens, like insect stings, certain foods, or medications.

We also prescribe EpiPen Jr., designed for children weighing between 33 lbs and 66 lbs, ensuring the right dosage during emergencies.

  • Immediate relief: EpiPen works rapidly, providing the crucial time you need to get to an emergency room.

  • Proven effectiveness: EpiPen is the first line of treatment due to clinical efficacy, trusted by medical professionals for its quick action.

EpiPen side effects

  • While EpiPen can be a life-saving tool for many, it’s essential to be aware of its potential side effects. Possible side effects include:

    • Fast, irregular, or “pounding” heartbeat

    • Breathing problems or wheezing

    • Paleness or flushed skin

    • A feeling of restlessness or nervousness

    • Dizziness or fainting

    • Nausea or vomiting

    • Sweating

    • Headache

    • Weakness or shakiness

    It's important to note that not everyone will experience these side effects, and in many cases, the benefits of using an EpiPen during an allergic reaction outweigh potential side effects. If you have concerns or have questions about when to use an EpiPen, consult with one of our doctors.*

    *If you are currently having symptoms of an emergency allergic reaction, call 911 and seek medical care immediately

How to use an EpiPen

General instructions may include:

  • Remove the safety cap

  • Grip the EpiPen with your dominant hand

  • Hold the device firmly against the outer thigh, at a right angle to the leg

  • Push the device forcefully into the thigh until you hear a click

  • Hold the device in place for a few seconds to ensure proper delivery

  • Seek immediate medical attention, even if symptoms improve

These steps are a general guide, and it is essential to refer to the specific instructions provided by your doctor.

While an EpiPen can be highly beneficial, it’s essential to know about its potential risks:

  • Incorrect injection site: EpiPens should be injected into the middle of the outer thigh. Injecting elsewhere could reduce its effectiveness or cause injury. If accidentally injected into your hands or feet, seek medical attention immediately.

  • Expired medication: Ensure your EpiPen hasn’t passed its expiry date. Its efficacy may decrease over time.

  • Possible interactions: Like all medications, there could be interactions with other drugs or conditions. Always inform your doctor about other medications you’re taking. Common interactions may include beta-blockers, antihistamines, certain asthma medications, and diuretics.

EpiPen FAQs

  • How much does an EpiPen cost?

    While the price of an EpiPen varies depending on various factors, such as the brand, insurance coverage, and pharmacy discounts, being a PlushCare member offers benefits. Out-of-pocket, the cost of generic EpiPen can start around $340, and the cost of brand-name EpiPen can start at $650. If you’re using insurance, depending on your plan, the cost may be partially or fully covered.

    As a PlushCare member, you can use our Prescription Discount Card and in-app Rx Price Finder to save on the out-of-pocket cost and find the pharmacy with the lowest price. On average, our members saved 42% on EpiPen with our discount card.

  • When to use EpiPen vs Benadryl?

    While both an EpiPen and Benadryl can help manage certain allergic reactions, they have different functions.

    EpiPens combat life-threatening reactions such as breathing difficulty and face or throat swelling. Benadryl is for milder reactions like itching and rashes.

    Benadryl is not meant to be a substitute for an EpiPen and should not be used in place of epinephrine for severe reactions. In all cases, it is important to consult your doctor for guidance on which medication to use in specific situations.

  • What happens if you use an EpiPen without needing it?

    If you use an EpiPen without needing it, the most common side effects include an increased heart rate, shakiness, and anxiety. These side effects are usually temporary and should subside over time. However, you should seek medical attention after using an EpiPen, even if it was not required, to address any concerns.

  • How long is an EpiPen good for?

    EpiPens have an expiration date printed on their packaging. It is important to keep track of the expiration date and renew your EpiPen before it expires. Expired EpiPens may not deliver the appropriate dose of epinephrine and could potentially be less effective in providing the desired response.

How to get an EpiPen online

Step 1: Book an appointment

Step 1

Book an appointment to request an EpiPen.

Book your same-day appointment from anywhere.

Step 2

Talk to your clinician about getting a prescription for an EpiPen.

Visit a board-certified doctor on your smartphone or computer.

Step 3

Pick up your EpiPen.

We can send prescriptions to any local pharmacy. Prescriptions are provided at the doctor’s discretion.

EpiPen prescription pricing details

How it works

To get a new or refill on your EpiPen prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


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