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Nexium Review

January 25, 2019 Read Time - 8 minutes

About Author

Jennifer is a freelance writer in the Midwest who writes about a variety of topics but especially enjoys educating people about their health and the health of their pets.

You’ve probably seen Nexium on the shelves of your local pharmacy and wondered if it would help your heartburn or other conditions caused by excess stomach acid. Let’s talk about what Nexium is used for, what side effects it can cause, and what you should know before you start taking it. Then we’ll look at reviews from people who’ve taken Nexium to help you decide whether or not it’s right for you.

What is Nexium?

Nexium is the brand name for esomeprazole, a proton pump inhibitor that reduces the amount of acid in the stomach. It’s used to treat gastroesophageal reflux disease (GERD) and other conditions that result from too much stomach acid. Nexium is available without a prescription. It is not intended for quick relief of heartburn symptoms.

Nexium Side Effects

Nexium can cause side effects that range from mild to life-threatening. Mild side effects you may experience include:

  • Constipation
  • Diarrhea
  • Drowsiness
  • Dry mouth
  • Gas
  • Headache
  • Nausea
  • Stomach pain

If you experience any of the following serious side effects, you should contact a doctor immediately:

  • Kidney problems. Symptoms may include blood in your urine, little or no urination, rapid weight gain, or swelling.
  • Low magnesium. Symptoms may include fast or irregular heart rate, dizziness, tremors (shaking) or jerking muscle movements, feeling jittery, muscle spasms in your hands and feet, muscle cramps, cough, or choking feeling.
  • New or worsening symptoms of lupus, such as joint pain and a rash on your cheeks or arms that gets worse in sunlight.
  • Seizure (convulsions)
  • Severe stomach pain, diarrhea that is watery or bloody

Long-term use of Nexium may lead to osteoporosis, vitamin B-12 deficiency, or stomach growths. You should discuss these risks with your doctor.

Nexium precautions

You should tell your doctor before using Nexium if you’ve ever had:

  • Low magnesium levels
  • Lupus
  • Osteoporosis or low bone mineral density (osteopenia)
  • Severe liver disease

Nexium can also interact with many medications. Tell your doctor about any medications you take, especially:

  • Antifungal medication like ketoconazole or voriconazole
  • Cilostazol
  • Clopidogrel
  • Diazepam
  • Digoxin
  • HIV/AIDS medication like atazanavir, nelfinavir, or saquinavir
  • Iron-containing medicines (ferrous fumarate, ferrous gluconate, ferrous sulfate, and others)
  • Methotrexate
  • Mycophenolate mofetil
  • Rifampin
  • St. John’s wort
  • Tacrolimus
  • Warfarin (Coumadin, Jantoven)

Nexium Reviews

From, here are user reviews of Nexium.

12/12/18 – "My doctor prescribe Nexium 40mg after endoscopy result that I’ve hiatus hinea and gastritis. The next day woke up feeling terrible, stomach discomfort burping the whole time. I don’t even have this symptoms before taking Nexium. By evening I felt my whole body so weak, can’t sleep , anxiety, heart palpitation. Next morning, were slightly better but because I did not know it was the effect of the medicine I continue to take. By evening I felt like dying, the next morning admitted to hospital for IV drip . Stay a night and the doctor said which probably could be viral infection. But after discharge , I took Nexium again. True enough the whole attack happen again. I did not take today, but the side effect is still there. Hopefully it will go off soon. Not bearable. This drugs done more damage to me and not helping at all."

12/1/18 – "Hi..So I was taking Nexium 40 mg. I took it for a month. It didn’t really work. I kept taking it thinking that maybe it takes time , but all I can say is it made my Anxiety worse! Every morning my ears were ringing so loud & my head felt fuzzy. I hated that feeling! I Would feel chest pains as well. My GI Dr. Said that was from heartburn, but honestly I knew it was the Nexium. I still keep taking it like a dummy because people I knew had a great experience with this Med… In the end I threw them away. Everyone is different & this for me was just toxic. Try it out & see how it goes. It works for some people :)"

11/16/18 – "I thought the Nexium Clear Minis would be a good choice since they’re so small they should be very easy to swallow. Today I think I aspirated the capsule as I took it early this morning and coughed it up finally this evening. In the windpipe it didn’t dissolve like it would in the esophagus and stomach so it was partially intact. Scary and relieved that it didn’t go further into my lungs!!!"

6/6/18 – "I started taking Omeprazole 20mg 25 years ago, then continue with esomeprazole and Nexium, no stop, I can’t quit, heartburn is coming back immediately even taking only water, no food. With Nexium, I’m able to eat almost all food without heartburn. Regardless of potential side effect, the doctor advised not to try to quit. My acid reflux is not treatable but Nexium perfectly works for me. No side effects or discomfort >20 years of my experience"

4/25/18 – "I have been taking nexium for over 14 years now and can not speak highly enough of this drug. Before Nexium I was eating quikezze like they were lollies. Now one 20mg dose all this time daily with the only side effect being gas in the mornings. This has been a wonder drug for me."

3/24/18 – "I started Proton Pump Inhibitors after cancer treatment in 1998. I started with a mild medicine and progressed as things got worse to Nexium twice a day. I haven’t had the side affects others seem to have had so I guess I am lucky in that way. It has helped the acid reflux for sure. But one side effect I haven’t seen here is ED. For Men taking this medication, if you begin to experience ED consult your doc and see if there is something else that could be used."

Nexium reviews from

1/3/19 – Rated Nexium (Esomeprazole) for Gastritis:
I have taken Nexium off and on for many years at a low dosage (20 mg) due to a range of GI issues including gastritis. I have found that it is fast acting and has really relieved my symptoms.

5/4/18 – Rated Nexium (Esomeprazole) for Gastric Ulcer:
The very first day I try nexium it work, I’m on the 14days trial , so far so good no complaints

7/25/18 – Rated Nexium (Esomeprazole) for Gastritis:
I have excessive gastric acid upon eating stimulating food like spices and proteins. That can cause either diarrhea or constipation. For the latter, I have resorted to Nexium on several occasions (such as right now on the toilet) and it provides relief in as little as 5-10 minutes. Also I find it helpful to take it right before bed, so that I can wake up feeling relieved in my stomach.

8/12/18 – Rated Nexium (Esomeprazole) for Gastritis:
Stay away from this drug it will deplete all your b12 calcium magnesium potassium vitamins and minerals. Which are your body’s lifeline. I ended up in the hospital with an irregular heartbeat was admitted for 3 days no one knew what caused it until I did a blood serum test that revealed what damage nexium had done in 3 months of taking it. I Prayed and started taking all the vitamins and minerals I needed. And Thank You Jesus that I’m better every day. God is Good.

4/27/16 – Rated Nexium (Esomeprazole) for Peptic Ulcer:
I took nexium for two weeks and I noticed a difference the first 4-5 days. I experienced heartburn quite a but at nighttime and while taking this product I did not get it. So I was able to eat all my favorite spicy foods and not experience heartburn afterwards I was very pleased with this product and will definitely buy it again.!

Nexium Reviews from WebMD

3/29/18 – I have been on Nexium for over 15 years, I started with 40 MG and when the paid increased last year, I started buy it over the counter and got the 20 Mg instead of the 40. I take one every morning, I have not ever had any side effects at all. It works great for me and I will continue to take it as long as I need to. I find it very effective.

6/21/16 – I have been on Nexium since it first came on the market.I started on Nexium 20mg but am now on 40mg. I have GERD, Hiatus Hernia, esophageal muscle spasms(which mimic a heart attack), a torturous esophagus(which it causing the food to block up. In the beginning it helped but as the years have gone on I will wake up choking with a sensation going up my throat.I have many of the side effects that I have read here but hadn’t know that it was the Nexium. I am having more pain and vomiting, excessive gas, tingling in my feet and hands, excessive weight gain, fluid retention(on fluid tablets to try and relieve the swelling), muscle jerking,nausea, vomiting,stomach pain, polyps. I eat small meals but even then it still blocks causing severe pain and then vomiting. I am being referred back to my GI specialist as my GP said the medication is not working as well as it should and that it needs reviewing. I am so glad that I am not the only one who has experienced these sided effects.

Questions about Nexium?

If you aren’t sure whether or not you should take Nexium, feel free to make an online appointment with one of our trusted doctors to talk about your concerns, questions, and medical conditions.

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