- Mental Health
- Depression
Trazodone
Trazodone (Desyrel) online prescription available
If you are suffering from depression, trazodone (Desyrel) can help. Get a new prescription or refill of trazodone from a board-certified doctor online.*
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Effective treatment for depression
Improve sleep, ease anxiety
Take control of your mental health
*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.
About trazodone (Desyrel)
Trazodone is considered a selective serotonin reuptake inhibitor (SSRI), which helps restore the balance of serotonin in the brain. Trazodone can not only help improve mood, appetite, and energy levels, but also decrease insomnia and anxiety related to depression.
Trazodone is used to treat depression and is available only by prescription. It is available in a brand formulation as Desyrel, as well as under other brand names.
Trazodone may be prescribed as an oral tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed trazodone, be sure to complete the full course of the antidepressant unless your doctor specifically tells you to stop. If you don’t complete your prescription, the antidepressant may not fully treat your mental health concerns.
Trazodone (Desyrel) uses
There is one FDA-approved use for trazodone, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for the following reason. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.
Depression
Trazodone is FDA-approved to treat depression in patients with major depressive disorder (MDD). It can help improve mood, reduce anxiety, and treat insomnia related to depression.
Desyrel may also be prescribed off-label to treat sleep issues related to other physical and mental illnesses.
Trazodone side effects
The side effects associated with taking Desyrel are typically mild. Most Desyrel side effects are associated with tiredness. Common side effects of trazodone may include:
Dizziness or drowsiness
Diarrhea or constipation
Weight loss
Other side effects, which are less common but might be more severe, could include:Severe restlessness
Serotonin syndrome
Fast or pounding heartbeats
Tell your doctor if you notice any of these side effects, or if you develop any other new or worsening symptoms. The use of Desyrel in children under age 18 is not recommended.
How to take trazodone
Your pharmacist will provide you with instructions on how to take your trazodone prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Trazodone can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The starting dose of trazodone is typically 150 mg/day, but your doctor may increase your dose by 50 mg/day every 3–4 days as needed.
You should take trazodone after a meal or snack. Don't stop taking trazodone (Desyrel) suddenly or you may experience withdrawal symptoms, such as worsening depression or agitation. Call your doctor before stopping the medicine.
What to avoid while taking Desyrel
Desyrel has 609 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as other drugs.
Possible drug interactions with Desyrel include:
St. John's Wort
Other medications for mental illness, including MAO inhibitors
Diuretics (water pills)
Blood thinners, including warfarin
Medicine for migraine headaches
Talk to your doctor before you drink alcohol. Alcohol can increase the nervous system side effects of Desyrel, such as dizziness, drowsiness, and trouble concentrating.
Avoid hazardous activity until you know how Desyrel will affect you. Avoid getting up too quickly from a sitting or lying position or you may feel dizzy.
Medication alternatives to trazodone (Desyrel)
If your healthcare provider prefers to put you on another treatment altogether, they may suggest other selective serotonin reuptake inhibitors (SSRIs) or an antidepressant in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
Major depressive disorder
Desyrel prescription FAQs
How much does Desyrel cost?
Depending on your pharmacy, Desyrel costs around $14 for fifteen 50 mg tablets without insurance. Generic brands, such as trazodone hydrochloride, may be even more affordable.
How can I refill my Desyrel prescription?
Desyrel is only available by prescription, so you will need to see a board-certified doctor to get a refill on your prescription. To get started, book a virtual appointment with one of our top rated board-certified doctors. After a qualifying evaluation, your prescription will be sent to your local pharmacy for pickup.
Who should not take Desyrel?
To make sure Desyrel is safe for you, tell your doctor if you have certain medical conditions, such as:
Liver or kidney disease
Heart disease or history of heart attack
A blood clotting disorder
Bipolar disorder (manic depression)
Glaucoma
Seizures or epilepsy
Long QT syndrome
Suicidal thoughts
What time of day should Desyrel be taken?
Take Desyrel after a meal or snack as directed by your doctor. If you experience drowsiness after taking Desyrel, take your dose before bed.
What happens if you take Desyrel on an empty stomach?
If you take Desyrel on an empty stomach, you may experience dizziness and/or lightheadedness.
What happens if I miss a dose of Desyrel?
If you miss a dose of Desyrel, take the missed dose as soon as you remember. Skip the missed dose if it’s almost time for your next dose. Avoid taking two doses to make up for a missed dose.
What happens if I take too much Desyrel?
If you've taken too much Desyrel, seek emergency medical attention or contact your local poison control center. Overdose symptoms can include extreme drowsiness, vomiting, or an irregular heartbeat.
3 simple steps to request your trazodone (Desyrel) prescription online today
Step 1
Book a Desyrel prescription request appointment.
Book a same day appointment from anywhere.
Step 2
Talk to your medical provider regarding your Desyrel prescription.
Visit with a doctor on your smartphone or computer.
Step 3
Pick up your Desyrel prescription.
We can send prescriptions to any local pharmacy.
Trazodone (Desyrel) prescription pricing details
How pricing works
To get a new or refill on your trazodone prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$16.99/month
First month free
Visits
Copay
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
- We accept these insurance plans and many more:
Paying without insurance
Membership
$16.99/month
First month free
Visits
$129
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129.
If we're unable to treat you, we'll provide a full refund.
Desyrel prescription resources
Sources:
PlushCare is dedicated to providing you with accurate and trustworthy health information.
Food and Drug Administration. Desyrel prescription label. Accessed on November 21, 2022. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018207s032lbl.pdf
Mayo Clinic. Trazodone (Oral Route). Accessed on November 21, 2022. https://www.mayoclinic.org/drugs-supplements/trazodone-oral-route/description/drg-20061280
MedlinePlus. Trazodone. Accessed on November 21, 2022. https://medlineplus.gov/druginfo/meds/a681038.html#:~:text=Trazodone%20is%20used%20to%20treat,that%20helps%20maintain%20mental%20balance
PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.