Astelin (azelastine) prescription available online 

If you are suffering from allergies or ongoing nasal symptoms, Astelin (azelastine) can help. Get a new prescription or refill of azelastine from a board-certified doctor online.*

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Ease nasal or allergy symptoms

Available as a nasal spray or oral dose

FDA-approved to treat seasonal allergic rhinitis

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Astelin (azelastine) 

Azelastine is considered an antihistamine, which reduces the effects of histamines on the body. Histamines can produce symptoms such as sneezing, runny nose, watery eyes, and itching.

Azelastine nasal spray is used to treat seasonal allergic rhinitis. It can also treat ongoing nasal symptoms that aren't caused by allergies. Azelastine is available only by prescription. It is available in a generic formulation as well as under different brand names, including Astelin.

Azelastine may be prescribed as a nasal spray or oral dose. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed azelastine, be sure to complete the full course of the nasal spray unless your doctor specifically tells you to stop. If you don’t complete your prescription, the nasal spray may not fully treat your nasal symptoms.

Astelin uses

There are several FDA-approved uses for azelastine, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Seasonal allergic rhinitis

    Azelastine nasal spray is FDA-approved to treat seasonal allergic rhinitis in adults and children five years and older. Astelin can help reduce nasal discomfort and treat allergy symptoms such as runny nose, sneezing, and itchy nose.

  • Nasal symptoms

    Azelastine nasal spray is FDA-approved to treat ongoing nasal symptoms, such as runny nose, itchy nose, and sneezing, that are not caused by allergies. Azelastine may be used to treat non-allergy nasal symptoms in adults and children over the age of 12.

Astelin side effects

The side effects associated with taking azelastine are typically mild. Most azelastine side effects are associated with a bitter taste in the mouth. Azelastine has some common side effects. They may include:

    • Bitter taste in your mouth

    • Drowsiness or tiredness

    • Dry mouth

    Other side effects, which are less common but might be more severe, could include:

    • Allergic reaction

    • Blurred vision

    • Nasal burning

    • Chest pain or tightness

    Ask your doctor for medical advice about side effects if you notice any adverse effects, or if you develop any other new or concerning symptoms. The use of Astelin nasal spray is approved in children over the age of five.

How to take Astelin (azelastine)

Your pharmacist will provide you with instructions on how to take your azelastine prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Azelastine can come in different forms and doses, so be sure to follow the specific instructions on your prescription. Before using this medication for the first time, you'll need to prime the bottle by removing the blue dust cover. Then, hold the bottle upright with two fingers on the spray pump, put your thumb on the bottom of the bottle, press upward, and release until a fine mist appears.

To use Astelin nasal spray:

  1. Keep your head tilted downward. Place the spray tip about one-half inch into your nostril. Hold the bottle upright and aim the spray tip toward the back of your nose.

  2. Close the other nostril with a finger. Press the pump one time and sniff gently.

  3. Repeat the same process in the other nostril.

What to avoid while taking azelastine

Azelastine has 199 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or dietary supplements, as well as other drugs. 

Possible drug interactions with azelastine nasal spray include:

  • Amifampridine

  • Bupropion

  • Donepezil

  • Pitolisant

  • Cimetidine

Ask your doctor for medical advice before drinking alcohol. If you drink alcohol while taking Astelin, you may experience increased nervous system side effects such as dizziness, drowsiness, and difficulty concentrating.

Medication alternatives to azelastine

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another nasal spray or antihistamine in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Astelin prescription FAQs

  • How much does azelastine cost?

    Depending on your pharmacy, azelastine nasal spray (137 mcg/inh) costs around $37 for 30 mL without insurance. Azelastine nasal spray is a generic brand, and brand names may cost more.

  • How can I refill my azelastine prescription?

    To refill your azelastine prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take azelastine?

    To make sure azelastine nasal spray is safe for you, tell your doctor if you have kidney disease or if you're taking any other medications to treat allergy symptoms.

  • How many times a day can you use azelastine nasal spray?

    Adults and children over 12 years old typically use two sprays in each nostril once daily. Avoid using more than four sprays in each nostril per day.

  • How long does it take azelastine to wear off?

    Azelastine typically lasts 12 hours. Your doctor may recommend taking azelastine hydrochloride once or twice a day.

  • Is it OK to use azelastine long term?

    Yes, it's safe to use azelastine long term to treat nasal or allergy symptoms.

  • What drugs does azelastine interact with?

    Possible drug interactions with azelastine nasal spray include:

    • Amifampridine

    • Bupropion

    • Donepezil

    • Pitolisant

    • Cimetidine

    Avoid taking Astelin with alcohol or other central nervous system depressants, such as sedatives, tranquilizers, sleep medicines, and antihistamines. Central nervous system depressants can cause extreme drowsiness when used with Astelin.

  • What happens if I miss a dose of azelastine?

    If you miss a dose of azelastine nasal spray, take the missed dose as soon as you remember. Skip the missed dose if it’s almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much azelastine?

    If you've taken too much azelastine, seek emergency medical attention or contact your local poison control center. Contact your local poison control center immediately if someone has accidentally swallowed the medication.

3 simple steps to request your azelastine prescription today 

Step 1

Book an azelastine prescription request appointment.

Book a same day appointment from anywhere.

Step 2

Talk to your medical provider regarding your azelastine prescription.

Visit with a doctor on your smartphone or computer.

Step 3

Pick up your azelastine prescription.

We can send prescriptions to any local pharmacy.

Azelastine prescription pricing details

How pricing works

To get a new or refill on your azelastine prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.

Astelin prescription resources


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