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10 types of ACE inhibitor medications

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About ACE inhibitors

ACE inhibitors are medications designed to lower blood pressure. They’re often prescribed to help treat high blood pressure, but they’re also used for other conditions. There are 10 types of prescription ACE inhibitors.

What ACE inhibitors treat

The most common condition treated with ACE inhibitors is high blood pressure. The drugs are designed to relax the arteries and veins to lower blood pressure. These medications inhibit the production of an enzyme that narrows veins and arteries.

Other conditions are also treated with angiotensin-converting enzyme inhibitors (ACE inhibitors). Coronary artery disease, for example, can be treated with ACE inhibitors. Below, take a look at how ACE inhibitors help with coronary artery disease and learn more about the uses of these medications for other health conditions.

  • Coronary artery disease

    Coronary artery disease (CAD) is a narrowing or blockage of the coronary arteries due to plaque buildup. When left untreated, CAD can lead to angina (chest pain), heart failure, heart attack, and arrhythmia (irregular heart rhythm). ACE inhibitors can decrease the risk of death or a major cardiovascular event in patients with coronary artery disease. These medications are beneficial for patients who already have diabetes too.

  • Heart failure

    Heart failure is when blood doesn’t pump as efficiently as it should. Various factors can lead to heart failure, including CAD, hypertension, faulty heart valves, and heart muscle damage. ACE inhibitor use is a common treatment approach for patients with heart failure. These medications can improve hemodynamics, decrease symptoms of fatigue and dyspnea, correct hyponatremia, increase exercise capacity, and provide other benefits. Also, ACE inhibitors improve heart failure by reducing afterload, preload, and systolic wall stress.

  • Diabetes

    Diabetes mellitus is a chronic metabolic condition indicated by high blood glucose (blood sugar) levels. Unmanaged diabetes causes many complications and may contribute to heart disease and other cardiovascular diseases. Doctors may prescribe ACE inhibitors to patients with diabetes mellitus. This medication's primary role is to decrease the rate of progression of diabetic neuropathy, such as diabetic retinopathy (eye damage). They can prevent or delay micro and macrovascular complications of diabetes and are also the first-line antihypertensive agents in patients with this chronic condition. The ACE inhibitors can prevent impaired renal function, heart-related adverse events, and to a lesser extent, peripheral nerve function problems in diabetic individuals.

  • Some chronic kidney diseases

    Chronic kidney disease is when the kidneys are so damaged they cannot filter blood efficiently. ACE inhibitors are more effective than other antihypertensive drugs in preventing renal failure progression in non-diabetic and diabetic patients. These medications reduce systemic blood pressure and intraglomerular pressure and decrease proteinuria (unfiltered protein) and chronic kidney disease.

  • Heart attack

    Heart attack or acute myocardial infarction results from a blockage of the artery that sends blood and oxygen to the heart. ACE inhibitors decrease the risk of heart attacks by widening blood vessels and making it easier for the heart to function correctly. They protect and strengthen the weakened heart. For that reason, doctors may prescribe ACE inhibitors to heart attack patients.

  • Migraine

    A migraine is a moderate or severe headache in the form of throbbing pain on one side of the head. These blood pressure medications can decrease the frequency and severity of migraine attacks.

  • Scleroderma

    Scleroderma is an uncommon condition indicated by hard, thickened areas of skin and problems with blood vessels and internal organs. It is an autoimmune condition meaning the body’s immune system starts attacking the connective tissue under the skin or around blood vessels and internal organs. Doctors may prescribe these blood pressure medications to treat scleroderma renal crisis, a complication of this autoimmune disease. They help because the main feature of this complication is severe hypertension.

Types of ACE inhibitors available online

The 10 ACE inhibitor medications are benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, and trandolapril. Below, you can look at different types of ACE inhibitors available online.

  • Captopril ACE inhibitors

    Captopril ACE inhibitors are most often used to treat high blood pressure and some types of congestive heart failure. These drugs improve survival and decrease the risk of heart failure after a heart attack in patients with ventricular hypertrophy. Doctors may also prescribe captopril to treat renal disease in patients with diabetes i.e. diabetic nephropathy.

    Captopril is sometimes taken with other medications to treat high blood pressure and heart failure.

    Examples of Captopril include:

  • Ramipril ACE inhibitors

    Ramipril ACE inhibitors are often used to treat high blood pressure and heart failure and are also prescribed to patients after a heart attack. It is also combined with other hypertension medications, such as felodipine.

    Examples of ramipril include:

  • Benazepril ACE inhibitors

    Benazepril ACE inhibitors are often used to treat hypertension but may also help with heart failure and diabetic renal disease. To treat high blood pressure, doctors may prescribe it in combination with other drugs, such as amlodipine and hydrochlorothiazide.

    Examples of benazepril include:

  • Quinapril ACE inhibitors

    Quinapril ACE inhibitors, like other medications from this class, are used to treat high blood pressure, prescribed to heart failure patients, and used to improve kidney function in patients with diabetes.

    Examples of quinapril include:

  • Enalapril ACE inhibitors

    Enalapril ACE inhibitors are used to treat high blood pressure. It is also used to treat kidney disease related to diabetes.

    Examples of enalapril include:

How ACE inhibitors work

ACE inhibitors prevent an enzyme in the body from producing angiotensin II, a compound that narrows veins and arteries. More precisely, ACE inhibitors act on the angiotensin-converting enzyme ACE to prevent the conversion of angiotensin I into angiotensin II.

Narrowing the veins and arteries can cause high blood pressure and decrease the heart's ability to pump properly. Plus, angiotensin II substances can also release hormones that raise blood pressure.

  • Side effects of ACE inhibitors

    When taken as prescribed, ACE inhibitors are generally well tolerated. However, they can still cause some side effects.

    The more common side effects of ACE inhibitors include:

    • Dry cough

    • Fatigue and/or weakness

    • Headache

    • Dizziness

    • Drowsiness

    • Hyperkalemia (high potassium levels)

      In rare cases, ACE inhibitors may cause serious side effects. These can include:

    • Rash

    • Nausea or upset stomach

    • Taste abnormalities, e.g., noticeable metallic taste

    • Swelling of some tissues, such as the throat, due to an allergic reaction

    • Decrease in white blood cells

    • Kidney failure

    • Jaundice

  • ACE inhibitor risks

    ACE inhibitors are generally safe, but there are some risks if you have other medical conditions or take certain medications.

    Before you take a prescribed ACE inhibitor, be sure to tell your doctor if you have any of the following conditions or issues:

    • History of angioedema

    • Severe kidney disease

    • Renal artery stenosis (disease of arteries that supply blood to the kidney)

    • Pregnancy or breastfeeding

  • ACE inhibitor drug interactions 

    When you begin a new medication, tell your doctor about any other medicines, supplements, or herbs you take. Some drugs that might interact with an ACE inhibitor include:

    • Non-steroidal anti-inflammatory drugs (NSAIDs)

    • Angiotensin receptor blockers

    • Medications that affect sodium or potassium levels

    • Medications that affect kidneys

ACE inhibitors you can get online

  • Lotensin (Benazepril)

    Lotensin treats high blood pressure, diabetic kidney disease, and heart failure. The dosage of Lotensin depends on whether a patient is also taking diuretics or not. Those who take diuretics start with a 5 mg dosage of Lotensin daily. On the flip side, patients who aren’t taking diuretics begin with 10 mg daily. Maintenance dosages range from 20 to 40 mg, taken once or twice daily.

  • Altace (Ramipril)

    Like other ACE inhibitors, Altace treats high blood pressure and other conditions such as heart failure. It is available in capsules at various dosages, such as 1.25 mg, 2.5 mg, 5 mg, and 10 mg. Patients who aren’t taking diuretics usually start with 2.5 mg daily, whereas their counterparts start with 1.25 mg.

  • Vasotec (Enalapril)

    Vasotec is an ACE inhibitor that comes in the form of a white, oval, scored tablet. Besides tablet form, it is also available as a solution. Initial hypertension and heart failure dosages are around 2.5 mg to 5 mg once a day. The maximum dose is 40 mg once a day or 20 mg twice a day.

  • Accupril (Quinapril)

    Accupril ACE inhibitor comes in oral tablet form. How much you take depends on whether you’re also taking diuretics. Patients who aren’t taking diuretics usually start with 10 mg to 20 mg once a day. Maintenance dosages vary from 20 to 80 mg once a day or are divided into two smaller doses.

  • Lotrel (Amlodipine & Benazepril)

    Lotrel is a combination of ACE inhibitor benazepril and calcium channel blocker amlodipine.  It works to relax arteries and veins to improve blood flow. As a result, it can manage high blood pressure, prevent stroke or heart attack, and manage kidney problems such as chronic kidney disease. Dosages may vary, but patients usually start with one pill a day with or without food.

ACE inhibitors FAQs

  • How should I take ACE inhibitors? 

    You should take angiotensin-converting enzyme inhibitors according to the doctor’s recommendations. These medications are usually taken on an empty stomach one hour before meals or in the morning with breakfast. Ideally, it would be best if you took your ACE inhibitors simultaneously every day.

  • Who shouldn’t take ACE inhibitors?

    People with a history of angioedema and severe kidney failure shouldn’t take ACE inhibitors. Also, these medications aren’t suitable for pregnant or breastfeeding women.

  • How long does it take for ACE inhibitors to work?

    The angiotensin-converting enzyme inhibitors may start working within a few hours to lower blood pressure, but it may take a few weeks to take full effect.

  • What should I avoid with ACE inhibitors?

    You should avoid over-the-counter NSAIDs when taking these drugs because they may cause the body to retain water and sodium. This can reduce the effects of ACE inhibitors. You should also avoid taking the drugs irregularly or deciding not to use them because you feel better.

  • What drugs are ACE inhibitors?

    Angiotensin-converting enzyme inhibitors are anti-hypertensive medications. Drugs classified as ACE inhibitors are benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, and trandolapril.

  • What is the most popular ACE inhibitor?

    The most popular ACE inhibitors are lisinopril, enalapril, and benazepril.

  • What is the role of ACE inhibitors?

    As the name suggests, the role of angiotensin-converting enzyme inhibitors is angiotensin-converting enzyme inhibition, i.e., they work to relax blood vessels and allow more blood to flow through. This makes it easier for the heart to function. When veins and arteries narrow, the heart is forced to work harder, weakening its function.

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Step 3: pick up at local pharmacy

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We can send prescriptions to any local pharmacy.

ACE inhibitor pricing details

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