Tapazole (Methimazole) prescription available online 

If you are suffering from hyperthyroidism, methimazole can help. Get a new prescription or refill of methimazole today from a board-certified doctor online.*

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Several FDA-approved uses

Trusted telehealth for thyroid care

Reduce symptoms of hyperthyroidism

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About methimazole (Tapazole)

Methimazole is an antithyroid agent that prevents the thyroid gland from producing too much thyroid hormone.

Methimazole is used to treat hyperthyroidism. Methimazole is available only by prescription. It is available in a generic formulation under different brand names, including Tapazole.

Methimazole may be prescribed as an oral tablet or liquid suspension. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed methimazole, complete the entire course of the antithyroid agent unless your doctor specifically tells you to stop. If you don’t complete your prescription, the thyroid medication may not fully treat your hyperthyroidism.

Methimazole uses

There are several FDA-approved uses for methimazole, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe methimazole for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Hyperthyroidism

    Methimazole is FDA-approved to treat patients with Graves' disease with hyperthyroidism or toxic multi-nodular goiter when surgery or radioactive iodine therapy is not an appropriate treatment option.

    Methimazole may also be prescribed to reduce the symptoms of hyperthyroidism to prepare for thyroid surgery (thyroidectomy) or radioactive iodine therapy.

Methimazole side effects

  • The side effects associated with taking methimazole are typically mild. Most Methimazole side effects are associated with gastrointestinal discomfort. Methimazole has some common side effects. Possible side effects may include:

    • Nausea, vomiting, and upset stomach

    • Headache, dizziness, and drowsiness

    • Rash, itching, or skin discoloration

    Other side effects, which are less common but might be more severe, could include:

    • Sudden weakness and cold symptoms, such as sore throat

    • Swollen glands in your neck or jaw

    • Signs of liver problems, such as unusual tiredness and dark urine

    Tell your doctor if you notice any of these side effects. Ask your doctor for medical advice about side effects if you develop any other new or concerning symptoms.

    Methimazole may be prescribed in younger children with mild hyperthyroidism who present symptoms of Graves' disease.

How to take methimazole

Your pharmacist will provide you with instructions on how to take your methimazole prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Methimazole can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The starting dose for adults can range from 15 mg to 60 mg daily, given in three doses. The maintenance dose ranges from 5 mg to 15 mg daily.

Methimazole is typically taken once every eight hours. Take your medication regularly to keep a steady amount of methimazole in your body at all times. Because storage temperature ranges differ according to manufacturers, ask your doctor for storage instructions.

What to avoid while taking methimazole

Methimazole has 55 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other drugs, dietary supplements, and nonprescription drugs.

Possible drug interactions with methimazole include:

  • Blood thinners, such as warfarin

  • Digoxin, digitalis, and theophylline

  • Beta-blockers, such as atenolol, carvedilol, and propranolol

Avoid drinking alcohol while taking methimazole, as alcohol consumption may increase the risk of liver problems and severe side effects. Avoid spending time around people who are sick or have infections.

Medication alternatives to methimazole

If your healthcare provider prefers to put you on another treatment, they may suggest another antithyroid agent in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

  • Hyperthyroidism


Methimazole prescription FAQs

  • How much does methimazole cost?

    Depending on your pharmacy, methimazole costs around $23 for ninety 5 mg tablets without insurance. Methimazole is a generic medication, and brand names may cost more.

  • How can I refill my methimazole prescription?

    To refill your methimazole prescription, book a virtual appointment with a board-certified PlushCare doctor. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take methimazole?

    Tell your doctor if you have certain medical conditions, such as:

    • Liver disease

    • Blood cell disorders, such as decreased white blood cells (leukopenia) or aplastic anemia

    • Weakened immune system

    • Decreased white blood cells

    • Allergic reactions

    Methimazole should not be taken during pregnancy or while breastfeeding. If you become pregnant while taking methimazole, tell your doctor immediately.

  • What happens if you touch methimazole?

    Methimazole may cause skin and eye irritation. It can also cause a skin-discoloring effect.

  • What happens if you take methimazole and don't need it?

    Taking methimazole when you don't need it can cause serious side effects, such as:

    • Irregular heart rhythms

    • Symptoms of heart failure

    • Rapid heart rate

    • Loss of bone density

    If your doctor advises you to stop taking methimazole, contact your local waste disposal company or provincial poison control center (for Canadian residents) to properly dispose of your medication.

  • How long does it take to feel better on methimazole?

    For patients taking methimazole, it typically takes a few weeks to months to notice symptom improvement.

  • What happens if I miss a dose of methimazole?

    If you miss a dose of methimazole, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • What happens if I take too much methimazole?

    If you've taken too much methimazole, seek medical help or contact your local poison control center.

3 simple steps to request your methimazole prescription today 

Step 1: Book an appointment

Step 1

Book a methimazole prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your methimazole prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your methimazole prescription.

We can send prescriptions to any local pharmacy.

Methimazole prescription pricing details

How pricing works

To get a new or refill on your methimazole prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.


PlushCare is dedicated to providing you with accurate and trustworthy health information.

PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.