Prozac (fluoxetine) online prescription available

If you are suffering from mental health concerns, Prozac is one antidepressant medication that can help. Get a same-day prescription or refill of Prozac from a caring, board-certified doctor online.*

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Telehealth support for your mental health

Personalized treatment for depression and anxiety

Several FDA-approved uses

*Prescriptions are provided at the doctor’s discretion. Learn more about our controlled substances policy and how you can save up to 80% with our prescription discount card.

About Prozac 

Prozac, an antidepressant medication, belongs to the selective serotonin reuptake inhibitors (SSRIs) class. Like other SSRIs, Prozac affects the chemical messengers (neurotransmitters) communicating between brain cells.

Prozac is used to treat major depressive disorder (MDD), premenstrual dysphoric disorder (PMDD), obsessive-compulsive disorder (OCD), anxiety, panic disorder, and bulimia nervosa. Prozac is available only by prescription. It is available in a generic formulation and under different brand names, including fluoxetine.

Prozac may be prescribed as a capsule. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.

If you're prescribed Prozac, complete the entire selective serotonin reuptake inhibitor course unless your doctor specifically tells you to stop. If you don’t finish your prescription, the antidepressant medication may not fully treat your mental health condition.

Prozac uses

There are several FDA-approved uses for Prozac, but your healthcare provider may also prescribe it off-label to treat other medical conditions.

Your PlushCare doctor may prescribe Prozac for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.

  • Major depressive disorder (MDD)

    Prozac is FDA-approved to for the acute and maintenance treatment of major depressive disorder in adult and pediatric patients over the age of 8. It can also help treat premenstrual dysphoric disorder (PMDD).

    Prozac may be prescribed with olanzapine to treat depressive episodes associated with bipolar disorder or treatment-resistant depression.

  • Obsessive-compulsive disorder (OCD)

    Prozac is FDA-approved to treat obsessive-compulsive disorder (OCD) in adult and pediatric patients over the age of 7.

  • Bulimia nervosa

    Prozac is FDA-approved to treat binge-eating and purging behaviors in adults with moderate to severe bulimia nervosa.

  • Panic disorder

    Prozac is FDA-approved to treat panic disorder, with and without agoraphobia, in adult patients. Prozac helps decrease the frequency of panic attacks and anxiety symptoms.

    Prozac may also be prescribed for other anxiety disorders, including generalized anxiety disorder (GAD) and post traumatic stress disorder (PTSD).

What are the pros and cons?



  • Low impact of missed doses

  • Clinically effective for depression and anxiety

  • One of the first SSRIs, widely used for decades


  • Can interact with many other medications

  • Stopping suddenly can lead to withdrawal symptoms

  • Can cause upset stomach, sleep problems, and sexual side effects

Prozac side effects

  • The side effects associated with taking Prozac are typically mild. Most Prozac side effects are associated with gastrointestinal discomfort.

    Prozac has some common side effects. They may include:

    • Sleeping problems and abnormal dreams

    • Headache, dizziness, and drowsiness

    • Yawning and tiredness

    • Upset stomach, loss of appetite, and diarrhea

    • Decreased sex drive

    Other side effects, which are less common but might be more severe, could include:

    • Blurred vision, tunnel vision, or eye pain

    • Fast or pounding heartbeats

    • Serotonin syndrome

    You should call your doctor if you notice any adverse effects, or if you develop any other new or worsening symptoms. The use of Prozac in young children under age 7 is not advised because it can cause suicidal thoughts and unusual tiredness.

How to take Prozac

Your pharmacist will provide you with instructions on how to take your Prozac prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Prozac can come in different doses, so be sure to follow the specific instructions on your prescription. The initial dose of Prozac typically ranges from 10 mg to 20 mg once daily.

It may take up to four weeks before your mental health improves. Keep using Prozac as prescribed and tell your doctor if your symptoms do not improve.

What to avoid while taking Prozac

Prozac has 654 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Possible drug interactions with Prozac include:

  • Other antidepressants

  • St. John's Wort

  • Migraine headache medication

  • ADHD and narcolepsy medication

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

Alcohol can increase adverse reactions to Prozac, including drowsiness, tiredness, and trouble concentrating. Talk to your doctor before drinking alcohol while taking fluoxetine.

Medication alternatives to Prozac

If your healthcare provider prefers to put you on another treatment altogether, they may suggest another selective serotonin reuptake inhibitor or antidepressant medication in another drug class. Here are some common doctor-recommended alternatives based on your health issue:

Prozac prescription FAQs

  • How much does Prozac cost?

    Depending on your pharmacy, Prozac costs around $556 for thirty 20 mg capsules without insurance. Fortunately, generic brands, such as fluoxetine, offer an affordable alternative.

  • How can I refill my Prozac prescription?

    To refill your Prozac prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms, your doctor can send an electronic prescription to your local pharmacy.

  • Who should not take Prozac?

    To make sure if Prozac is safe for you, tell your doctor if you have:

    • Liver disease

    • Urination problems

    • Diabetes

    • Narrow-angle glaucoma

    • Seizures or epilepsy

    • Bipolar disorder (manic depression)

  • What happens if I miss a dose of Prozac?

    If you miss a dose of Prozac, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.

  • How long does Prozac take to fully kick in?

    For depression, Prozac may start to improve symptoms within two weeks. For most people, Prozac takes 4–6 weeks to take full effect.

  • What does Prozac do in the first week?

    It's normal to experience side effects, such as nausea, drowsiness, and increased anxiety, during the first week of taking fluoxetine. These side effects should improve after a few weeks.

  • What happens if I take too much Prozac?

    If you've taken too much Prozac, seek emergency medical attention or contact your local poison control center.

  • Can I buy Prozac over the counter?

    Prozac (fluoxetine) is available by prescription only and can't be bought over the counter. While Prozac is safe and effective for many people, it carries the risk of serious side effects and is contraindicated for some people. Only a doctor can diagnose your specific condition and ensure Prozac is the right treatment for you. There are other medications available to treat depression and anxiety, and a doctor can recommend the best option based on your specific needs. Chat with a caring, board-certified doctor online today to discuss Prozac as a treatment option.

3 simple steps to request your Prozac prescription today 

Step 1: Book an appointment

Step 1

Book a Prozac prescription request appointment.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Prozac prescription.

Visit with a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Prozac prescription.

We can send prescriptions to any local pharmacy.

Prozac prescription pricing details

How pricing works

To get a new or refill on your Prozac prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • Cigna

Paying without insurance



First month free



30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129.

Book an appointment

If we're unable to treat you, we'll provide a full refund.

Prozac prescription resources


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PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.