
Nasal decongestant prescriptions available online
Learn how decongestants can help congestion with a consultation from one of our board-certified primary care doctors online. Get a new prescription or refill for decongestants from a top-rated doctor online.*
About nasal decongestants
Nasal decongestants are medications designed to relieve congestion by reducing swelling, inflammation, and mucus formation in the nasal and sinus tissues. Decongestants have no other effect on congestion symptoms, such as a stuffy nose or sneezing.
Decongestants may be taken orally to help reduce nose congestion, sinus congestion, or eye congestion. They can also be sprayed directly in the nose or installed in the eye for a localized effect.
Most decongestants are used to help treat congestion caused by the common cold, flu, sinusitis, or allergic rhinitis, but over-the-counter decongestants are also available. There are three types of decongestants: nasal, oral, and ophthalmic applied medications.
What decongestants treat
The most common condition treated with decongestants is allergic rhinitis. Decongestants are designed to narrow the blood vessels in your nasal and airway membranes, which helps drain mucus so you can breathe easier.
Other conditions are also treated with decongestants. Your doctor may recommend an over-the-counter decongestant or prescription medication to treat congestion associated with the common cold, flu virus, and other illnesses.
Types of decongestants available online
The three types of decongestant medications: nasal, oral, and ophthalmic. Some prescription and OTC medicines may just contain decongestant medicine, while others are sold as an "all-in-one" solution that contains decongestants, pain relief medicine, or antihistamines.
Nasal spray decongestants
Some nasal sprays shouldn't be used for more than three days. If you become dependent on nasal sprays or nose drops, you may feel more stuffed up when you stop using them. This is called "rebound nasal congestion."
Examples of nasal decongestant sprays include:
Oral nasal decongestants
Unlike nasal sprays, oral decongestants do not cause rebound congestion. However, they're usually not as effective or fast-acting as nasally administered decongestants.
Examples of oral decongestant medicines include:
Ophthalmic decongestants
Examples of eye drops include:
How decongestants work
When your body detects a virus, it sends extra blood to the blood vessels in your nose to fight the virus. In turn, your nasal tissues and blood vessels become swollen, which makes it harder to breathe through your nose.
Decongestants act to shrink swollen blood vessels, which helps relieve swelling, inflammation, and mucus formation within the nasal passages. Swollen tissue inside the nose shrinks, and air can pass through more easily.
Side effects of decongestants
When taken as prescribed, decongestants are generally well tolerated. However, they can still cause some side effects. The most common side effects of decongestants include:
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Drowsiness
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Irritation of the lining of your nose
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Headache
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Dry mouth
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Feeling restless or agitated
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Skin rash
In rare cases, decongestants may cause serious side effects. These can include:
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Fast, pounding, or uneven heartbeat
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Severe dizziness or anxiety
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Easy bruising or bleeding
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Unusual weakness
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Unusually high blood pressure
Decongestant risks
Decongestants are generally safe, but there are some risks if you have other medical conditions or take certain medications.
Before you take a prescribed decongestant, be sure to tell your doctor if you have any of the following conditions or issues:
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High blood pressure
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Heart disease
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Urinary problems
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Diabetes
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Glaucoma
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Overactive thyroid gland (hyperthyroidism)
Decongestant drug interactions
When you begin a new medication, make sure to tell your doctor about any other medications, supplements, or herbs you’re taking. Some medications that might interact with a decongestant include:
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Blood pressure medications, including guanethidine, methyldopa, beta-blockers, and calcium channel blockers
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MAO inhibitors, including isocarboxazid, linezolid, and metaxalone
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Certain antidepressants
Avoid using more than one over-the-counter decongestant medicine unless your doctor says it's OK. Multiple medications may have similar active ingredients.
Decongestants FAQs
How should I take decongestants?
Who shouldn’t take decongestants?
Avoid taking decongestants if you have certain medical conditions, such as:
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High blood pressure
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Heart disease
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Urinary problems
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Diabetes
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Glaucoma
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Overactive thyroid gland (hyperthyroidism)
How long does it take for decongestants to work?
What should I avoid with decongestants?
Avoid taking oral decongestants with monoamine oxide inhibitors (MAOIs) and other antidepressants without your doctor's approval. Make sure to tell your doctor about any medications you're taking.
In addition, using nonprescription nasal sprays for more than 3–4 days can cause a rebound effect, which leads to worse nasal congestion after the decongestant wears off. Avoid using nasal sprays for OTC relief longer than needed.
What is the most effective decongestant?
With that said, the best decongestant will depend on your specific symptoms, type of congestion, and condition. Your healthcare professional can choose the best prescription for your congestion symptoms.
What does a decongestant do?
Can a doctor prescribe pseudoephedrine?
Fortunately, you can set an appointment with PlushCare’s doctors to buy pseudoephedrine online. The average appointment takes just 15 minutes and you can leave with a prescription that’s right for you, if you qualify.
What can doctors prescribe for congestion?
Combination products are also available. Some medications may combine decongestant medicine, antihistamines, and pain relievers for additional symptom relief.
3 simple steps to getting decongestants online

Book an appointment to discuss decongestants.

Talk to your board certified primary care doctor online.

Pick up your decongestants prescription from your online doctor.
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Decongestants resources
Sources:
PlushCare is dedicated to providing you with accurate and trustworthy health information.
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Mayo Clinic. Mayo Clinic Q and A: Decongestants can sometimes cause more harm than good. Accessed on October 26, 2022. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-decongestants-can-sometimes-cause-more-harm-than-good/#:~:text=Also%20avoid%20excess%20caffeine%20or,side%20effects%20through%20drug%20interaction.
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National Health Services. Decongestants. Accessed on October 26, 2022. https://www.nhs.uk/conditions/decongestants/
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National Library of Medicine. A placebo-controlled study of the nasal decongestant effect of phenylephrine and pseudoephedrine in the Vienna Challenge Chamber. Accessed on October 26, 2022. https://pubmed.ncbi.nlm.nih.gov/19230461/
PlushCare content is reviewed by MDs, PhDs, NPs, nutritionists, and other healthcare professionals. Learn more about our editorial standards and meet the medical team. The PlushCare site or any linked materials are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment.